| Full name: fibronectin leucine rich transmembrane protein 1 | Alias Symbol: MGC21624|SPG68 | ||
| Type: protein-coding gene | Cytoband: 11q13.1 | ||
| Entrez ID: 23769 | HGNC ID: HGNC:3760 | Ensembl Gene: ENSG00000126500 | OMIM ID: 604806 |
| Drug and gene relationship at DGIdb | |||
Expression of FLRT1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FLRT1 | 23769 | 210414_at | -0.0113 | 0.9779 | |
| GSE20347 | FLRT1 | 23769 | 210414_at | 0.1174 | 0.1721 | |
| GSE23400 | FLRT1 | 23769 | 210414_at | -0.0161 | 0.6796 | |
| GSE26886 | FLRT1 | 23769 | 210414_at | -0.0693 | 0.5631 | |
| GSE29001 | FLRT1 | 23769 | 210414_at | -0.1183 | 0.5144 | |
| GSE38129 | FLRT1 | 23769 | 210414_at | -0.2005 | 0.1000 | |
| GSE45670 | FLRT1 | 23769 | 210414_at | -0.0008 | 0.9944 | |
| GSE63941 | FLRT1 | 23769 | 210414_at | 0.4206 | 0.1145 | |
| GSE77861 | FLRT1 | 23769 | 210414_at | 0.0316 | 0.7850 | |
| GSE97050 | FLRT1 | 23769 | A_23_P47168 | -0.4676 | 0.2726 | |
| SRP133303 | FLRT1 | 23769 | RNAseq | -0.5137 | 0.0857 | |
| SRP159526 | FLRT1 | 23769 | RNAseq | 0.5390 | 0.2042 | |
| SRP219564 | FLRT1 | 23769 | RNAseq | -0.2822 | 0.6367 | |
| TCGA | FLRT1 | 23769 | RNAseq | -0.9041 | 0.0003 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FLRT1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of FLRT1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FLRT1 | 23769 | 6 | 5 | 19 | |
| GSE20123 | FLRT1 | 23769 | 6 | 5 | 19 | |
| GSE43470 | FLRT1 | 23769 | 1 | 3 | 39 | |
| GSE46452 | FLRT1 | 23769 | 8 | 4 | 47 | |
| GSE47630 | FLRT1 | 23769 | 3 | 7 | 30 | |
| GSE54993 | FLRT1 | 23769 | 3 | 0 | 67 | |
| GSE54994 | FLRT1 | 23769 | 5 | 5 | 43 | |
| GSE60625 | FLRT1 | 23769 | 0 | 4 | 7 | |
| GSE74703 | FLRT1 | 23769 | 1 | 1 | 34 | |
| GSE74704 | FLRT1 | 23769 | 4 | 3 | 13 | |
| TCGA | FLRT1 | 23769 | 17 | 10 | 69 |
Total number of gains: 54; Total number of losses: 47; Total Number of normals: 387.
Somatic mutations of FLRT1:
Generating mutation plots.
Highly correlated genes for FLRT1:
Showing top 20/261 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FLRT1 | NDNF | 0.744233 | 3 | 0 | 3 |
| FLRT1 | SLC7A10 | 0.727007 | 3 | 0 | 3 |
| FLRT1 | RNF167 | 0.724747 | 3 | 0 | 3 |
| FLRT1 | NEURL1 | 0.712152 | 3 | 0 | 3 |
| FLRT1 | ZNF580 | 0.695162 | 4 | 0 | 3 |
| FLRT1 | TNXB | 0.693874 | 3 | 0 | 3 |
| FLRT1 | MS4A3 | 0.69352 | 3 | 0 | 3 |
| FLRT1 | IFNA5 | 0.688312 | 3 | 0 | 3 |
| FLRT1 | CPNE6 | 0.67238 | 3 | 0 | 3 |
| FLRT1 | GPC5 | 0.663004 | 3 | 0 | 3 |
| FLRT1 | DNAJA4 | 0.656828 | 4 | 0 | 4 |
| FLRT1 | CALCOCO1 | 0.655049 | 4 | 0 | 3 |
| FLRT1 | TM4SF4 | 0.654784 | 5 | 0 | 5 |
| FLRT1 | PRPH | 0.652962 | 6 | 0 | 6 |
| FLRT1 | PGC | 0.651666 | 3 | 0 | 3 |
| FLRT1 | NTNG1 | 0.649308 | 3 | 0 | 3 |
| FLRT1 | OTUD5 | 0.642049 | 3 | 0 | 3 |
| FLRT1 | ZNF446 | 0.636575 | 4 | 0 | 3 |
| FLRT1 | CEMP1 | 0.632938 | 4 | 0 | 3 |
| FLRT1 | SYT2 | 0.630396 | 4 | 0 | 4 |
For details and further investigation, click here
