| Full name: solute carrier family 7 member 10 | Alias Symbol: asc-1 | ||
| Type: protein-coding gene | Cytoband: 19q13.11 | ||
| Entrez ID: 56301 | HGNC ID: HGNC:11058 | Ensembl Gene: ENSG00000130876 | OMIM ID: 607959 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC7A10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC7A10 | 56301 | 220868_s_at | -0.0634 | 0.8292 | |
| GSE20347 | SLC7A10 | 56301 | 220868_s_at | 0.0866 | 0.2386 | |
| GSE23400 | SLC7A10 | 56301 | 220868_s_at | -0.1610 | 0.0000 | |
| GSE26886 | SLC7A10 | 56301 | 220868_s_at | 0.4162 | 0.0000 | |
| GSE29001 | SLC7A10 | 56301 | 220868_s_at | -0.0425 | 0.7734 | |
| GSE38129 | SLC7A10 | 56301 | 220868_s_at | -0.1751 | 0.2477 | |
| GSE45670 | SLC7A10 | 56301 | 220868_s_at | -0.0172 | 0.8814 | |
| GSE63941 | SLC7A10 | 56301 | 220868_s_at | -0.0769 | 0.6245 | |
| GSE77861 | SLC7A10 | 56301 | 220868_s_at | -0.0533 | 0.6833 | |
| GSE97050 | SLC7A10 | 56301 | A_23_P108075 | -0.2315 | 0.6405 | |
| TCGA | SLC7A10 | 56301 | RNAseq | 1.1036 | 0.3029 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SLC7A10 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of SLC7A10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC7A10 | 56301 | 7 | 6 | 17 | |
| GSE20123 | SLC7A10 | 56301 | 7 | 5 | 18 | |
| GSE43470 | SLC7A10 | 56301 | 4 | 6 | 33 | |
| GSE46452 | SLC7A10 | 56301 | 47 | 1 | 11 | |
| GSE47630 | SLC7A10 | 56301 | 8 | 6 | 26 | |
| GSE54993 | SLC7A10 | 56301 | 17 | 3 | 50 | |
| GSE54994 | SLC7A10 | 56301 | 7 | 9 | 37 | |
| GSE60625 | SLC7A10 | 56301 | 9 | 0 | 2 | |
| GSE74703 | SLC7A10 | 56301 | 4 | 4 | 28 | |
| GSE74704 | SLC7A10 | 56301 | 6 | 3 | 11 | |
| TCGA | SLC7A10 | 56301 | 18 | 12 | 66 |
Total number of gains: 134; Total number of losses: 55; Total Number of normals: 299.
Somatic mutations of SLC7A10:
Generating mutation plots.
Highly correlated genes for SLC7A10:
Showing top 20/357 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC7A10 | FLRT1 | 0.727007 | 3 | 0 | 3 |
| SLC7A10 | SLC17A6 | 0.675345 | 3 | 0 | 3 |
| SLC7A10 | CYP2D6 | 0.67049 | 3 | 0 | 3 |
| SLC7A10 | ZNF483 | 0.670141 | 4 | 0 | 3 |
| SLC7A10 | CDK20 | 0.669133 | 4 | 0 | 4 |
| SLC7A10 | CNTN2 | 0.666485 | 4 | 0 | 3 |
| SLC7A10 | STXBP6 | 0.6662 | 3 | 0 | 3 |
| SLC7A10 | DPF3 | 0.663794 | 3 | 0 | 3 |
| SLC7A10 | NPHP1 | 0.659464 | 3 | 0 | 3 |
| SLC7A10 | ZNF580 | 0.658642 | 4 | 0 | 3 |
| SLC7A10 | NOXA1 | 0.657352 | 3 | 0 | 3 |
| SLC7A10 | FRS3 | 0.657298 | 3 | 0 | 3 |
| SLC7A10 | ATP8B3 | 0.652263 | 3 | 0 | 3 |
| SLC7A10 | HDAC11 | 0.651412 | 3 | 0 | 3 |
| SLC7A10 | SLC22A2 | 0.651067 | 3 | 0 | 3 |
| SLC7A10 | PPP1R12C | 0.649785 | 3 | 0 | 3 |
| SLC7A10 | TRPC5 | 0.643 | 3 | 0 | 3 |
| SLC7A10 | CDH23 | 0.631169 | 4 | 0 | 4 |
| SLC7A10 | ZNF81 | 0.628282 | 3 | 0 | 3 |
| SLC7A10 | GPD1 | 0.626054 | 6 | 0 | 4 |
For details and further investigation, click here
