| Full name: general transcription factor IIIC subunit 2 | Alias Symbol: KIAA0011|TFIIIC110 | ||
| Type: protein-coding gene | Cytoband: 2p23.3 | ||
| Entrez ID: 2976 | HGNC ID: HGNC:4665 | Ensembl Gene: ENSG00000115207 | OMIM ID: 604883 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of GTF3C2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GTF3C2 | 2976 | 212429_s_at | 0.3389 | 0.5311 | |
| GSE20347 | GTF3C2 | 2976 | 204366_s_at | 0.0904 | 0.5127 | |
| GSE23400 | GTF3C2 | 2976 | 212429_s_at | 0.2148 | 0.0003 | |
| GSE26886 | GTF3C2 | 2976 | 204366_s_at | 0.4105 | 0.0086 | |
| GSE29001 | GTF3C2 | 2976 | 212429_s_at | 0.0789 | 0.7149 | |
| GSE38129 | GTF3C2 | 2976 | 204366_s_at | 0.3358 | 0.0073 | |
| GSE45670 | GTF3C2 | 2976 | 204366_s_at | 0.1099 | 0.5630 | |
| GSE63941 | GTF3C2 | 2976 | 204366_s_at | 0.6235 | 0.0674 | |
| GSE77861 | GTF3C2 | 2976 | 204366_s_at | 0.2269 | 0.1524 | |
| GSE97050 | GTF3C2 | 2976 | A_23_P169887 | 0.3440 | 0.2151 | |
| SRP007169 | GTF3C2 | 2976 | RNAseq | -0.2182 | 0.5301 | |
| SRP008496 | GTF3C2 | 2976 | RNAseq | -0.2330 | 0.3261 | |
| SRP064894 | GTF3C2 | 2976 | RNAseq | 0.0356 | 0.8509 | |
| SRP133303 | GTF3C2 | 2976 | RNAseq | 0.0756 | 0.6634 | |
| SRP159526 | GTF3C2 | 2976 | RNAseq | 0.1580 | 0.5001 | |
| SRP193095 | GTF3C2 | 2976 | RNAseq | 0.2204 | 0.0233 | |
| SRP219564 | GTF3C2 | 2976 | RNAseq | -0.0295 | 0.9396 | |
| TCGA | GTF3C2 | 2976 | RNAseq | 0.1077 | 0.0183 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GTF3C2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of GTF3C2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GTF3C2 | 2976 | 11 | 2 | 17 | |
| GSE20123 | GTF3C2 | 2976 | 11 | 2 | 17 | |
| GSE43470 | GTF3C2 | 2976 | 3 | 1 | 39 | |
| GSE46452 | GTF3C2 | 2976 | 3 | 4 | 52 | |
| GSE47630 | GTF3C2 | 2976 | 8 | 0 | 32 | |
| GSE54993 | GTF3C2 | 2976 | 0 | 6 | 64 | |
| GSE54994 | GTF3C2 | 2976 | 10 | 0 | 43 | |
| GSE60625 | GTF3C2 | 2976 | 0 | 3 | 8 | |
| GSE74703 | GTF3C2 | 2976 | 3 | 0 | 33 | |
| GSE74704 | GTF3C2 | 2976 | 9 | 1 | 10 | |
| TCGA | GTF3C2 | 2976 | 37 | 2 | 57 |
Total number of gains: 95; Total number of losses: 21; Total Number of normals: 372.
Somatic mutations of GTF3C2:
Generating mutation plots.
Highly correlated genes for GTF3C2:
Showing top 20/778 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GTF3C2 | DNTTIP1 | 0.777739 | 3 | 0 | 3 |
| GTF3C2 | PLEKHG1 | 0.751142 | 3 | 0 | 3 |
| GTF3C2 | TMEM44 | 0.745284 | 3 | 0 | 3 |
| GTF3C2 | CNOT10 | 0.743292 | 3 | 0 | 3 |
| GTF3C2 | VMA21 | 0.743042 | 3 | 0 | 3 |
| GTF3C2 | SHC1 | 0.74074 | 3 | 0 | 3 |
| GTF3C2 | FMR1 | 0.73365 | 3 | 0 | 3 |
| GTF3C2 | NUDT5 | 0.732867 | 3 | 0 | 3 |
| GTF3C2 | KDELR2 | 0.729537 | 3 | 0 | 3 |
| GTF3C2 | C12orf73 | 0.720656 | 3 | 0 | 3 |
| GTF3C2 | CDC37 | 0.718189 | 3 | 0 | 3 |
| GTF3C2 | PIGL | 0.717918 | 3 | 0 | 3 |
| GTF3C2 | OTUD7B | 0.715056 | 3 | 0 | 3 |
| GTF3C2 | S100PBP | 0.714391 | 3 | 0 | 3 |
| GTF3C2 | PSMG3 | 0.714052 | 4 | 0 | 4 |
| GTF3C2 | TRMT12 | 0.713554 | 3 | 0 | 3 |
| GTF3C2 | CLEC16A | 0.713536 | 3 | 0 | 3 |
| GTF3C2 | ZNF513 | 0.713519 | 3 | 0 | 3 |
| GTF3C2 | NHSL1 | 0.712101 | 3 | 0 | 3 |
| GTF3C2 | STX16 | 0.707848 | 3 | 0 | 3 |
For details and further investigation, click here
