RNASEH1

 

Full name: ribonuclease H1 Alias Symbol: 
Type: protein-coding gene Cytoband: 2p25.3
Entrez ID: 246243 HGNC ID: HGNC:18466 Ensembl Gene: ENSG00000171865 OMIM ID: 604123
Drug and gene relationship at DGIdb

 

Expression of RNASEH1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 RNASEH1 246243 218497_s_at 0.5918 0.1140
GSE20347 RNASEH1 246243 218496_at 0.4729 0.0148
GSE23400 RNASEH1 246243 218496_at 0.3457 0.0000
GSE26886 RNASEH1 246243 218496_at 0.7474 0.0019
GSE29001 RNASEH1 246243 218497_s_at 0.8474 0.0007
GSE38129 RNASEH1 246243 218497_s_at 0.8475 0.0000
GSE45670 RNASEH1 246243 218497_s_at 0.5242 0.0060
GSE53622 RNASEH1 246243 122176 0.5478 0.0000
GSE53624 RNASEH1 246243 122176 0.6311 0.0000
GSE63941 RNASEH1 246243 218497_s_at 0.0743 0.8972
GSE77861 RNASEH1 246243 218497_s_at 0.7492 0.0218
GSE97050 RNASEH1 246243 A_23_P27167 0.5803 0.1393
SRP007169 RNASEH1 246243 RNAseq 0.8980 0.0479
SRP008496 RNASEH1 246243 RNAseq 0.6024 0.0683
SRP064894 RNASEH1 246243 RNAseq 0.3888 0.0009
SRP133303 RNASEH1 246243 RNAseq 0.4211 0.0005
SRP159526 RNASEH1 246243 RNAseq 0.6570 0.0245
SRP193095 RNASEH1 246243 RNAseq 0.4456 0.0000
SRP219564 RNASEH1 246243 RNAseq 0.2334 0.5051
TCGA RNASEH1 246243 RNAseq 0.0264 0.6436

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by RNASEH1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of RNASEH1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RNASEH1 246243 8 3 19
GSE20123 RNASEH1 246243 8 3 19
GSE43470 RNASEH1 246243 3 1 39
GSE46452 RNASEH1 246243 3 4 52
GSE47630 RNASEH1 246243 7 0 33
GSE54993 RNASEH1 246243 1 7 62
GSE54994 RNASEH1 246243 12 0 41
GSE60625 RNASEH1 246243 0 3 8
GSE74703 RNASEH1 246243 3 0 33
GSE74704 RNASEH1 246243 8 1 11
TCGA RNASEH1 246243 32 5 59

Total number of gains: 85; Total number of losses: 27; Total Number of normals: 376.  

 

Somatic mutations of RNASEH1:

 

Generating mutation plots.

 

Highly correlated genes for RNASEH1:

 

Showing top 20/2076 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RNASEH1C1orf2260.767948404
RNASEH1C1orf1310.745581707
RNASEH1FMR10.742108303
RNASEH1CPSF30.741644908
RNASEH1KTI120.737467303
RNASEH1PHF5A0.729855707
RNASEH1HAS30.728143404
RNASEH1YWHAG0.728122505
RNASEH1PPIL10.724546505
RNASEH1ARHGAP180.724207303
RNASEH1LAMTOR10.722584303
RNASEH1ACP10.722155907
RNASEH1MRPS230.719792707
RNASEH1SNRPG0.7162271009
RNASEH1WDR540.715902707
RNASEH1GEMIN60.71279411010
RNASEH1FXR10.711453907
RNASEH1ADCY30.709082907
RNASEH1LAP30.708686404
RNASEH1EPPK10.708123505

For details and further investigation, click here