CKAP5

 

Full name: cytoskeleton associated protein 5 Alias Symbol: ch-TOG|KIAA0097|TOG|TOGp
Type: protein-coding gene Cytoband: 11p11.2
Entrez ID: 9793 HGNC ID: HGNC:28959 Ensembl Gene: ENSG00000175216 OMIM ID: 611142
Drug and gene relationship at DGIdb

 

Expression of CKAP5:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CKAP5 9793 212832_s_at 0.7031 0.0145
GSE20347 CKAP5 9793 212832_s_at 0.5893 0.0009
GSE23400 CKAP5 9793 212832_s_at 0.6413 0.0000
GSE26886 CKAP5 9793 212832_s_at 1.2276 0.0000
GSE29001 CKAP5 9793 212832_s_at 0.9250 0.0006
GSE38129 CKAP5 9793 212832_s_at 0.6605 0.0000
GSE45670 CKAP5 9793 212832_s_at 0.6018 0.0010
GSE53622 CKAP5 9793 108373 0.8796 0.0000
GSE53624 CKAP5 9793 6624 0.9582 0.0000
GSE63941 CKAP5 9793 212832_s_at 0.9681 0.0151
GSE77861 CKAP5 9793 212832_s_at 0.8035 0.0023
GSE97050 CKAP5 9793 A_23_P135977 0.5583 0.1269
SRP007169 CKAP5 9793 RNAseq 1.9730 0.0001
SRP008496 CKAP5 9793 RNAseq 1.9354 0.0000
SRP064894 CKAP5 9793 RNAseq 0.7780 0.0004
SRP133303 CKAP5 9793 RNAseq 0.9654 0.0000
SRP159526 CKAP5 9793 RNAseq 0.8404 0.0027
SRP193095 CKAP5 9793 RNAseq 0.6563 0.0000
SRP219564 CKAP5 9793 RNAseq 0.7196 0.0004
TCGA CKAP5 9793 RNAseq 0.2330 0.0000

Upregulated datasets: 3; Downregulated datasets: 0.  

 

Survival by CKAP5 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of CKAP5:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CKAP5 9793 3 7 20
GSE20123 CKAP5 9793 3 6 21
GSE43470 CKAP5 9793 2 4 37
GSE46452 CKAP5 9793 8 5 46
GSE47630 CKAP5 9793 3 9 28
GSE54993 CKAP5 9793 3 1 66
GSE54994 CKAP5 9793 1 10 42
GSE60625 CKAP5 9793 0 0 11
GSE74703 CKAP5 9793 2 2 32
GSE74704 CKAP5 9793 2 4 14
TCGA CKAP5 9793 12 19 65

Total number of gains: 39; Total number of losses: 67; Total Number of normals: 382.  

 

Somatic mutations of CKAP5:

 

Generating mutation plots.

 

Highly correlated genes for CKAP5:

 

Showing top 20/2164 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CKAP5TMEM1380.779592707
CKAP5WDR540.775831707
CKAP5CMC10.774376303
CKAP5IRF2BP20.770475303
CKAP5PACS10.770214303
CKAP5LRP120.7632911011
CKAP5SLC39A30.761349404
CKAP5FMNL20.757568707
CKAP5ALKBH60.754637404
CKAP5COLGALT10.75353310010
CKAP5MARCKSL10.75060411011
CKAP5CAD0.74666712012
CKAP5SAC3D10.74465810010
CKAP5DNMT10.74417413011
CKAP5ACLY0.7436911011
CKAP5PLOD10.74163310010
CKAP5ARPC1B0.73806711011
CKAP5FMR10.73781303
CKAP5CEP1200.737534303
CKAP5PLAU0.73642211011

For details and further investigation, click here