GSTO1

 

Full name: glutathione S-transferase omega 1 Alias Symbol: GSTTLp28|P28
Type: protein-coding gene Cytoband: 10q25.1
Entrez ID: 9446 HGNC ID: HGNC:13312 Ensembl Gene: ENSG00000148834 OMIM ID: 605482
Drug and gene relationship at DGIdb

 

Expression of GSTO1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 GSTO1 9446 201470_at 0.4150 0.3113
GSE20347 GSTO1 9446 201470_at 0.6007 0.0007
GSE23400 GSTO1 9446 201470_at 0.9335 0.0000
GSE26886 GSTO1 9446 201470_at 1.2302 0.0000
GSE29001 GSTO1 9446 201470_at 0.6980 0.0119
GSE38129 GSTO1 9446 201470_at 0.7425 0.0000
GSE45670 GSTO1 9446 201470_at 0.6212 0.0034
GSE53622 GSTO1 9446 5588 0.7166 0.0000
GSE53624 GSTO1 9446 5588 1.0366 0.0000
GSE63941 GSTO1 9446 201470_at -0.6662 0.1264
GSE77861 GSTO1 9446 201470_at 1.1710 0.0035
GSE97050 GSTO1 9446 A_24_P304051 0.4608 0.1450
SRP007169 GSTO1 9446 RNAseq 3.3445 0.0000
SRP008496 GSTO1 9446 RNAseq 3.3851 0.0000
SRP064894 GSTO1 9446 RNAseq 1.0175 0.0003
SRP133303 GSTO1 9446 RNAseq 0.9787 0.0000
SRP159526 GSTO1 9446 RNAseq 1.4713 0.0042
SRP193095 GSTO1 9446 RNAseq 0.4748 0.0062
SRP219564 GSTO1 9446 RNAseq 0.3888 0.2659
TCGA GSTO1 9446 RNAseq 0.1808 0.0027

Upregulated datasets: 7; Downregulated datasets: 0.  


 

Survival by GSTO1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of GSTO1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 GSTO1 9446 1 9 20
GSE20123 GSTO1 9446 1 8 21
GSE43470 GSTO1 9446 0 7 36
GSE46452 GSTO1 9446 0 11 48
GSE47630 GSTO1 9446 2 14 24
GSE54993 GSTO1 9446 8 0 62
GSE54994 GSTO1 9446 1 10 42
GSE60625 GSTO1 9446 0 0 11
GSE74703 GSTO1 9446 0 5 31
GSE74704 GSTO1 9446 0 4 16
TCGA GSTO1 9446 6 28 62

Total number of gains: 19; Total number of losses: 96; Total Number of normals: 373.  


 

Somatic mutations of GSTO1:

 

Generating mutation plots.

 

Highly correlated genes for GSTO1:

 

Showing top 20/1656 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
GSTO1GHDC0.789196303
GSTO1SLC39A30.76512303
GSTO1CEP1200.757292303
GSTO1FMR10.75419303
GSTO1ALKBH60.746551404
GSTO1GNG100.744169303
GSTO1PSMB40.74057810010
GSTO1VPS350.740274303
GSTO1CHD30.738129303
GSTO1ALPK20.737373303
GSTO1KRTCAP20.736711404
GSTO1DHRSX0.736147303
GSTO1NUP350.734955303
GSTO1ZBED10.731713303
GSTO1KCTD130.725291303
GSTO1SNRPE0.7221210010
GSTO1WDR540.721016807
GSTO1AKR1B10.7207481109
GSTO1HAS30.720154504
GSTO1TIGD10.719597303

For details and further investigation, click here