| Full name: formin binding protein 4 | Alias Symbol: KIAA1014 | ||
| Type: protein-coding gene | Cytoband: 11p11.2 | ||
| Entrez ID: 23360 | HGNC ID: HGNC:19752 | Ensembl Gene: ENSG00000109920 | OMIM ID: 615265 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of FNBP4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FNBP4 | 23360 | 212232_at | -0.0292 | 0.9650 | |
| GSE20347 | FNBP4 | 23360 | 212232_at | 0.1223 | 0.3889 | |
| GSE23400 | FNBP4 | 23360 | 212232_at | 0.1026 | 0.1784 | |
| GSE26886 | FNBP4 | 23360 | 212232_at | -0.0412 | 0.9060 | |
| GSE29001 | FNBP4 | 23360 | 212232_at | -0.0247 | 0.9329 | |
| GSE38129 | FNBP4 | 23360 | 212232_at | 0.1093 | 0.4786 | |
| GSE45670 | FNBP4 | 23360 | 212232_at | -0.2041 | 0.1070 | |
| GSE53622 | FNBP4 | 23360 | 147935 | -0.1212 | 0.0512 | |
| GSE53624 | FNBP4 | 23360 | 147935 | -0.1617 | 0.0517 | |
| GSE63941 | FNBP4 | 23360 | 212232_at | -0.4526 | 0.3036 | |
| GSE77861 | FNBP4 | 23360 | 212232_at | 0.3386 | 0.1961 | |
| GSE97050 | FNBP4 | 23360 | A_23_P395595 | -0.1346 | 0.6566 | |
| SRP007169 | FNBP4 | 23360 | RNAseq | -0.5205 | 0.1882 | |
| SRP008496 | FNBP4 | 23360 | RNAseq | -0.3380 | 0.2005 | |
| SRP064894 | FNBP4 | 23360 | RNAseq | -0.4243 | 0.0833 | |
| SRP133303 | FNBP4 | 23360 | RNAseq | -0.1369 | 0.0434 | |
| SRP159526 | FNBP4 | 23360 | RNAseq | -0.1851 | 0.6537 | |
| SRP193095 | FNBP4 | 23360 | RNAseq | -0.0165 | 0.9018 | |
| SRP219564 | FNBP4 | 23360 | RNAseq | -0.0738 | 0.8336 | |
| TCGA | FNBP4 | 23360 | RNAseq | 0.0169 | 0.7161 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FNBP4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FNBP4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FNBP4 | 23360 | 3 | 7 | 20 | |
| GSE20123 | FNBP4 | 23360 | 3 | 6 | 21 | |
| GSE43470 | FNBP4 | 23360 | 1 | 4 | 38 | |
| GSE46452 | FNBP4 | 23360 | 8 | 5 | 46 | |
| GSE47630 | FNBP4 | 23360 | 3 | 9 | 28 | |
| GSE54993 | FNBP4 | 23360 | 3 | 0 | 67 | |
| GSE54994 | FNBP4 | 23360 | 1 | 11 | 41 | |
| GSE60625 | FNBP4 | 23360 | 0 | 0 | 11 | |
| GSE74703 | FNBP4 | 23360 | 1 | 2 | 33 | |
| GSE74704 | FNBP4 | 23360 | 2 | 4 | 14 | |
| TCGA | FNBP4 | 23360 | 10 | 20 | 66 |
Total number of gains: 35; Total number of losses: 68; Total Number of normals: 385.
Somatic mutations of FNBP4:
Generating mutation plots.
Highly correlated genes for FNBP4:
Showing top 20/241 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FNBP4 | GPBP1 | 0.786741 | 3 | 0 | 3 |
| FNBP4 | LARP4 | 0.771238 | 3 | 0 | 3 |
| FNBP4 | BRD2 | 0.74243 | 3 | 0 | 3 |
| FNBP4 | TRA2B | 0.739279 | 3 | 0 | 3 |
| FNBP4 | OPHN1 | 0.739105 | 3 | 0 | 3 |
| FNBP4 | ZNF830 | 0.729679 | 3 | 0 | 3 |
| FNBP4 | SEC63 | 0.723042 | 4 | 0 | 3 |
| FNBP4 | STK38L | 0.719102 | 3 | 0 | 3 |
| FNBP4 | INTS6 | 0.71725 | 3 | 0 | 3 |
| FNBP4 | TMCO4 | 0.70863 | 3 | 0 | 3 |
| FNBP4 | ZNF23 | 0.706907 | 3 | 0 | 3 |
| FNBP4 | UBR3 | 0.705755 | 3 | 0 | 3 |
| FNBP4 | COQ10B | 0.704083 | 3 | 0 | 3 |
| FNBP4 | PLEKHA3 | 0.700502 | 3 | 0 | 3 |
| FNBP4 | ZSCAN29 | 0.699241 | 3 | 0 | 3 |
| FNBP4 | ARHGAP35 | 0.694671 | 3 | 0 | 3 |
| FNBP4 | ZFP3 | 0.691822 | 3 | 0 | 3 |
| FNBP4 | METTL8 | 0.68793 | 3 | 0 | 3 |
| FNBP4 | PAN3 | 0.686986 | 5 | 0 | 5 |
| FNBP4 | ZNF567 | 0.685416 | 4 | 0 | 3 |
For details and further investigation, click here
