| Full name: coenzyme Q10B | Alias Symbol: FLJ13448 | ||
| Type: protein-coding gene | Cytoband: 2q33.1 | ||
| Entrez ID: 80219 | HGNC ID: HGNC:25819 | Ensembl Gene: ENSG00000115520 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of COQ10B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COQ10B | 80219 | 219397_at | 0.1808 | 0.7227 | |
| GSE20347 | COQ10B | 80219 | 219397_at | 0.0706 | 0.6951 | |
| GSE23400 | COQ10B | 80219 | 219397_at | 0.1378 | 0.0723 | |
| GSE26886 | COQ10B | 80219 | 219397_at | -0.0083 | 0.9827 | |
| GSE29001 | COQ10B | 80219 | 219397_at | -0.1664 | 0.5006 | |
| GSE38129 | COQ10B | 80219 | 219397_at | 0.1640 | 0.3146 | |
| GSE45670 | COQ10B | 80219 | 219397_at | -0.1032 | 0.5406 | |
| GSE53622 | COQ10B | 80219 | 55155 | 0.1055 | 0.2297 | |
| GSE53624 | COQ10B | 80219 | 55155 | -0.1170 | 0.1680 | |
| GSE63941 | COQ10B | 80219 | 219397_at | -1.2172 | 0.0238 | |
| GSE77861 | COQ10B | 80219 | 219397_at | 0.6727 | 0.0051 | |
| GSE97050 | COQ10B | 80219 | A_33_P3354858 | 0.0380 | 0.9128 | |
| SRP007169 | COQ10B | 80219 | RNAseq | -0.6666 | 0.0918 | |
| SRP008496 | COQ10B | 80219 | RNAseq | -0.4974 | 0.0189 | |
| SRP064894 | COQ10B | 80219 | RNAseq | -0.2048 | 0.2736 | |
| SRP133303 | COQ10B | 80219 | RNAseq | 0.2765 | 0.0320 | |
| SRP159526 | COQ10B | 80219 | RNAseq | -0.3232 | 0.2714 | |
| SRP193095 | COQ10B | 80219 | RNAseq | -0.2789 | 0.0286 | |
| SRP219564 | COQ10B | 80219 | RNAseq | -0.5309 | 0.1207 | |
| TCGA | COQ10B | 80219 | RNAseq | -0.1067 | 0.0452 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by COQ10B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COQ10B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COQ10B | 80219 | 10 | 2 | 18 | |
| GSE20123 | COQ10B | 80219 | 10 | 2 | 18 | |
| GSE43470 | COQ10B | 80219 | 3 | 1 | 39 | |
| GSE46452 | COQ10B | 80219 | 1 | 4 | 54 | |
| GSE47630 | COQ10B | 80219 | 4 | 5 | 31 | |
| GSE54993 | COQ10B | 80219 | 0 | 3 | 67 | |
| GSE54994 | COQ10B | 80219 | 11 | 8 | 34 | |
| GSE60625 | COQ10B | 80219 | 0 | 3 | 8 | |
| GSE74703 | COQ10B | 80219 | 2 | 1 | 33 | |
| GSE74704 | COQ10B | 80219 | 5 | 2 | 13 | |
| TCGA | COQ10B | 80219 | 22 | 9 | 65 |
Total number of gains: 68; Total number of losses: 40; Total Number of normals: 380.
Somatic mutations of COQ10B:
Generating mutation plots.
Highly correlated genes for COQ10B:
Showing top 20/210 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COQ10B | MUC6 | 0.758472 | 3 | 0 | 3 |
| COQ10B | RC3H2 | 0.754333 | 3 | 0 | 3 |
| COQ10B | UBR1 | 0.74092 | 3 | 0 | 3 |
| COQ10B | FOXJ2 | 0.729023 | 3 | 0 | 3 |
| COQ10B | GPR183 | 0.724381 | 3 | 0 | 3 |
| COQ10B | RAPGEF1 | 0.72099 | 3 | 0 | 3 |
| COQ10B | CHST15 | 0.720797 | 3 | 0 | 3 |
| COQ10B | TNFRSF10B | 0.718422 | 3 | 0 | 3 |
| COQ10B | LPCAT1 | 0.717681 | 3 | 0 | 3 |
| COQ10B | COX7A2L | 0.716424 | 3 | 0 | 3 |
| COQ10B | TMEM181 | 0.713141 | 3 | 0 | 3 |
| COQ10B | VAMP2 | 0.708636 | 3 | 0 | 3 |
| COQ10B | ZNF791 | 0.707556 | 3 | 0 | 3 |
| COQ10B | CLDN18 | 0.70468 | 3 | 0 | 3 |
| COQ10B | MED17 | 0.704209 | 3 | 0 | 3 |
| COQ10B | FNBP4 | 0.704083 | 3 | 0 | 3 |
| COQ10B | FGF7 | 0.703422 | 3 | 0 | 3 |
| COQ10B | GLIS2 | 0.693156 | 3 | 0 | 3 |
| COQ10B | GRIK2 | 0.693103 | 3 | 0 | 3 |
| COQ10B | SUPT7L | 0.692599 | 3 | 0 | 3 |
For details and further investigation, click here
