| Full name: La ribonucleoprotein domain family member 4 | Alias Symbol: PP13296 | ||
| Type: protein-coding gene | Cytoband: 12q13.12 | ||
| Entrez ID: 113251 | HGNC ID: HGNC:24320 | Ensembl Gene: ENSG00000161813 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of LARP4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LARP4 | 113251 | 212714_at | 0.0838 | 0.8529 | |
| GSE20347 | LARP4 | 113251 | 212714_at | 0.1563 | 0.3380 | |
| GSE23400 | LARP4 | 113251 | 212714_at | 0.1074 | 0.0751 | |
| GSE26886 | LARP4 | 113251 | 212714_at | -0.9640 | 0.0017 | |
| GSE29001 | LARP4 | 113251 | 212714_at | 0.2124 | 0.3127 | |
| GSE38129 | LARP4 | 113251 | 212714_at | 0.2634 | 0.0232 | |
| GSE45670 | LARP4 | 113251 | 212714_at | 0.1631 | 0.2576 | |
| GSE53622 | LARP4 | 113251 | 27630 | 0.0595 | 0.3625 | |
| GSE53624 | LARP4 | 113251 | 27630 | 0.2189 | 0.0000 | |
| GSE63941 | LARP4 | 113251 | 212714_at | -0.3293 | 0.5371 | |
| GSE77861 | LARP4 | 113251 | 212714_at | 0.5664 | 0.1200 | |
| GSE97050 | LARP4 | 113251 | A_33_P3456341 | 0.1127 | 0.7143 | |
| SRP007169 | LARP4 | 113251 | RNAseq | -0.4357 | 0.1396 | |
| SRP008496 | LARP4 | 113251 | RNAseq | 0.0911 | 0.7056 | |
| SRP064894 | LARP4 | 113251 | RNAseq | -0.2181 | 0.2935 | |
| SRP133303 | LARP4 | 113251 | RNAseq | 0.5915 | 0.0002 | |
| SRP159526 | LARP4 | 113251 | RNAseq | 0.0802 | 0.7765 | |
| SRP193095 | LARP4 | 113251 | RNAseq | -0.0798 | 0.2975 | |
| SRP219564 | LARP4 | 113251 | RNAseq | 0.0659 | 0.8321 | |
| TCGA | LARP4 | 113251 | RNAseq | -0.0581 | 0.2025 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LARP4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LARP4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LARP4 | 113251 | 8 | 1 | 21 | |
| GSE20123 | LARP4 | 113251 | 8 | 1 | 21 | |
| GSE43470 | LARP4 | 113251 | 3 | 0 | 40 | |
| GSE46452 | LARP4 | 113251 | 8 | 1 | 50 | |
| GSE47630 | LARP4 | 113251 | 11 | 2 | 27 | |
| GSE54993 | LARP4 | 113251 | 0 | 5 | 65 | |
| GSE54994 | LARP4 | 113251 | 3 | 2 | 48 | |
| GSE60625 | LARP4 | 113251 | 0 | 0 | 11 | |
| GSE74703 | LARP4 | 113251 | 3 | 0 | 33 | |
| GSE74704 | LARP4 | 113251 | 5 | 1 | 14 | |
| TCGA | LARP4 | 113251 | 14 | 11 | 71 |
Total number of gains: 63; Total number of losses: 24; Total Number of normals: 401.
Somatic mutations of LARP4:
Generating mutation plots.
Highly correlated genes for LARP4:
Showing top 20/452 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LARP4 | C2CD2 | 0.869465 | 3 | 0 | 3 |
| LARP4 | GMCL1 | 0.814839 | 3 | 0 | 3 |
| LARP4 | ERCC6 | 0.805844 | 3 | 0 | 3 |
| LARP4 | VPS26B | 0.789001 | 3 | 0 | 3 |
| LARP4 | PANK1 | 0.787616 | 3 | 0 | 3 |
| LARP4 | TM9SF3 | 0.786091 | 3 | 0 | 3 |
| LARP4 | FNBP4 | 0.771238 | 3 | 0 | 3 |
| LARP4 | CNOT10 | 0.764199 | 3 | 0 | 3 |
| LARP4 | KIAA2026 | 0.762392 | 3 | 0 | 3 |
| LARP4 | CDC37 | 0.759273 | 3 | 0 | 3 |
| LARP4 | THAP5 | 0.756623 | 3 | 0 | 3 |
| LARP4 | CWC25 | 0.752413 | 3 | 0 | 3 |
| LARP4 | ZNF564 | 0.743923 | 3 | 0 | 3 |
| LARP4 | ANKIB1 | 0.74167 | 4 | 0 | 3 |
| LARP4 | PIGN | 0.740759 | 3 | 0 | 3 |
| LARP4 | NAA35 | 0.740655 | 3 | 0 | 3 |
| LARP4 | GLUD2 | 0.734927 | 3 | 0 | 3 |
| LARP4 | LATS1 | 0.733078 | 3 | 0 | 3 |
| LARP4 | FAN1 | 0.730584 | 3 | 0 | 3 |
| LARP4 | SMAD3 | 0.72686 | 3 | 0 | 3 |
For details and further investigation, click here
