| Full name: neuraminidase 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 6p21.33 | ||
| Entrez ID: 4758 | HGNC ID: HGNC:7758 | Ensembl Gene: ENSG00000204386 | OMIM ID: 608272 |
| Drug and gene relationship at DGIdb | |||
Expression of NEU1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NEU1 | 4758 | 208926_at | 0.8028 | 0.0265 | |
| GSE20347 | NEU1 | 4758 | 208926_at | 0.7034 | 0.0015 | |
| GSE23400 | NEU1 | 4758 | 208926_at | 0.5074 | 0.0000 | |
| GSE26886 | NEU1 | 4758 | 208926_at | 0.3018 | 0.1789 | |
| GSE29001 | NEU1 | 4758 | 208926_at | -0.0163 | 0.9395 | |
| GSE38129 | NEU1 | 4758 | 208926_at | 0.8165 | 0.0000 | |
| GSE45670 | NEU1 | 4758 | 208926_at | 0.6534 | 0.0007 | |
| GSE53622 | NEU1 | 4758 | 29172 | 0.6956 | 0.0000 | |
| GSE53624 | NEU1 | 4758 | 29172 | 0.8006 | 0.0000 | |
| GSE63941 | NEU1 | 4758 | 208926_at | 0.3575 | 0.4993 | |
| GSE77861 | NEU1 | 4758 | 208926_at | 0.5713 | 0.0250 | |
| GSE97050 | NEU1 | 4758 | A_24_P394533 | 0.5002 | 0.1585 | |
| SRP007169 | NEU1 | 4758 | RNAseq | 0.4153 | 0.3203 | |
| SRP008496 | NEU1 | 4758 | RNAseq | 0.4157 | 0.1217 | |
| SRP064894 | NEU1 | 4758 | RNAseq | 0.7853 | 0.0004 | |
| SRP133303 | NEU1 | 4758 | RNAseq | 0.5888 | 0.0000 | |
| SRP159526 | NEU1 | 4758 | RNAseq | 0.9088 | 0.0000 | |
| SRP193095 | NEU1 | 4758 | RNAseq | 0.5842 | 0.0000 | |
| SRP219564 | NEU1 | 4758 | RNAseq | 0.8408 | 0.0683 | |
| TCGA | NEU1 | 4758 | RNAseq | -0.0472 | 0.3466 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NEU1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NEU1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NEU1 | 4758 | 5 | 1 | 24 | |
| GSE20123 | NEU1 | 4758 | 5 | 1 | 24 | |
| GSE43470 | NEU1 | 4758 | 5 | 1 | 37 | |
| GSE46452 | NEU1 | 4758 | 1 | 10 | 48 | |
| GSE47630 | NEU1 | 4758 | 7 | 4 | 29 | |
| GSE54993 | NEU1 | 4758 | 2 | 1 | 67 | |
| GSE54994 | NEU1 | 4758 | 11 | 4 | 38 | |
| GSE60625 | NEU1 | 4758 | 0 | 1 | 10 | |
| GSE74703 | NEU1 | 4758 | 5 | 0 | 31 | |
| GSE74704 | NEU1 | 4758 | 2 | 0 | 18 | |
| TCGA | NEU1 | 4758 | 16 | 16 | 64 |
Total number of gains: 59; Total number of losses: 39; Total Number of normals: 390.
Somatic mutations of NEU1:
Generating mutation plots.
Highly correlated genes for NEU1:
Showing top 20/1583 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NEU1 | DENND3 | 0.778532 | 3 | 0 | 3 |
| NEU1 | APOC1 | 0.725357 | 5 | 0 | 5 |
| NEU1 | SLC52A2 | 0.721777 | 4 | 0 | 4 |
| NEU1 | MARCKSL1 | 0.720547 | 9 | 0 | 9 |
| NEU1 | ATP6V1C1 | 0.719966 | 9 | 0 | 9 |
| NEU1 | C8orf82 | 0.718499 | 3 | 0 | 3 |
| NEU1 | GRAMD1A | 0.715463 | 5 | 0 | 4 |
| NEU1 | CXCL16 | 0.710983 | 5 | 0 | 5 |
| NEU1 | TFDP2 | 0.701851 | 5 | 0 | 5 |
| NEU1 | HSPG2 | 0.701686 | 3 | 0 | 3 |
| NEU1 | TMEM138 | 0.699888 | 7 | 0 | 7 |
| NEU1 | TTYH3 | 0.698064 | 6 | 0 | 6 |
| NEU1 | MFAP2 | 0.695654 | 9 | 0 | 9 |
| NEU1 | TRIM47 | 0.689495 | 3 | 0 | 3 |
| NEU1 | FOXS1 | 0.685929 | 3 | 0 | 3 |
| NEU1 | PLAU | 0.683755 | 9 | 0 | 9 |
| NEU1 | FAM89A | 0.683364 | 3 | 0 | 3 |
| NEU1 | TNFRSF1A | 0.683186 | 3 | 0 | 3 |
| NEU1 | KDELR3 | 0.68305 | 8 | 0 | 8 |
| NEU1 | APMAP | 0.681948 | 9 | 0 | 8 |
For details and further investigation, click here
