BRMS1

 

Full name: BRMS1 transcriptional repressor and anoikis regulator Alias Symbol: DKFZP564A063
Type: protein-coding gene Cytoband: 11q13.2
Entrez ID: 25855 HGNC ID: HGNC:17262 Ensembl Gene: ENSG00000174744 OMIM ID: 606259
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of BRMS1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 BRMS1 25855 215631_s_at 0.8842 0.0494
GSE20347 BRMS1 25855 215631_s_at 0.6795 0.0002
GSE23400 BRMS1 25855 215631_s_at 0.3692 0.0000
GSE26886 BRMS1 25855 215631_s_at 0.1032 0.7158
GSE29001 BRMS1 25855 215631_s_at 0.4682 0.0190
GSE38129 BRMS1 25855 215631_s_at 0.7070 0.0000
GSE45670 BRMS1 25855 215631_s_at 0.5980 0.0001
GSE53622 BRMS1 25855 37788 0.7506 0.0000
GSE53624 BRMS1 25855 37788 0.7686 0.0000
GSE63941 BRMS1 25855 215631_s_at 0.7845 0.0378
GSE77861 BRMS1 25855 215631_s_at 0.5363 0.0031
GSE97050 BRMS1 25855 A_33_P3367017 0.6755 0.2589
SRP007169 BRMS1 25855 RNAseq 1.2512 0.0236
SRP008496 BRMS1 25855 RNAseq 1.5001 0.0012
SRP064894 BRMS1 25855 RNAseq 0.6984 0.0103
SRP133303 BRMS1 25855 RNAseq 0.9314 0.0000
SRP159526 BRMS1 25855 RNAseq 0.5182 0.0239
SRP193095 BRMS1 25855 RNAseq 0.4887 0.0001
SRP219564 BRMS1 25855 RNAseq 0.8324 0.0379
TCGA BRMS1 25855 RNAseq 0.2793 0.0000

Upregulated datasets: 2; Downregulated datasets: 0.  

 

Survival by BRMS1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of BRMS1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 BRMS1 25855 9 4 17
GSE20123 BRMS1 25855 9 4 17
GSE43470 BRMS1 25855 6 1 36
GSE46452 BRMS1 25855 11 3 45
GSE47630 BRMS1 25855 8 5 27
GSE54993 BRMS1 25855 3 0 67
GSE54994 BRMS1 25855 8 5 40
GSE60625 BRMS1 25855 0 3 8
GSE74703 BRMS1 25855 4 0 32
GSE74704 BRMS1 25855 7 2 11
TCGA BRMS1 25855 25 6 65

Total number of gains: 90; Total number of losses: 33; Total Number of normals: 365.  

 

Somatic mutations of BRMS1:

 

Generating mutation plots.

 

Highly correlated genes for BRMS1:

 

Showing top 20/1547 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
BRMS1PSMG30.783489606
BRMS1DPP30.75002111011
BRMS1CCDC860.747957707
BRMS1ADRM10.74552410010
BRMS1CFL10.74013710010
BRMS1MICALCL0.727196303
BRMS1GEN10.726174404
BRMS1MRPL140.723365505
BRMS1SOGA10.722989303
BRMS1ZNF1140.721201303
BRMS1YIF1A0.72060413013
BRMS1UHRF10.719862606
BRMS1UBE2C0.71743511010
BRMS1RRP360.712664505
BRMS1EME10.712133504
BRMS1BANF10.71032611010
BRMS1RAD180.707589303
BRMS1STIP10.7059912011
BRMS1WDR740.70384111010
BRMS1RCC20.702395606

For details and further investigation, click here