| Full name: KN motif and ankyrin repeat domains 2 | Alias Symbol: KIAA1518 | ||
| Type: protein-coding gene | Cytoband: 19p13.2 | ||
| Entrez ID: 25959 | HGNC ID: HGNC:29300 | Ensembl Gene: ENSG00000197256 | OMIM ID: 614610 |
| Drug and gene relationship at DGIdb | |||
Expression of KANK2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KANK2 | 25959 | 218418_s_at | -1.3131 | 0.2280 | |
| GSE20347 | KANK2 | 25959 | 221068_at | -0.1605 | 0.0431 | |
| GSE23400 | KANK2 | 25959 | 218418_s_at | -0.4363 | 0.0161 | |
| GSE26886 | KANK2 | 25959 | 218418_s_at | 0.7623 | 0.0588 | |
| GSE29001 | KANK2 | 25959 | 218418_s_at | 0.2273 | 0.6092 | |
| GSE38129 | KANK2 | 25959 | 218418_s_at | -0.6666 | 0.2375 | |
| GSE45670 | KANK2 | 25959 | 218418_s_at | -2.3856 | 0.0000 | |
| GSE53622 | KANK2 | 25959 | 129018 | -1.1587 | 0.0000 | |
| GSE53624 | KANK2 | 25959 | 129018 | -0.8723 | 0.0000 | |
| GSE63941 | KANK2 | 25959 | 218418_s_at | -2.8205 | 0.0024 | |
| GSE77861 | KANK2 | 25959 | 221068_at | -0.1950 | 0.1539 | |
| GSE97050 | KANK2 | 25959 | A_23_P50426 | -1.0960 | 0.1134 | |
| SRP007169 | KANK2 | 25959 | RNAseq | 2.8715 | 0.0000 | |
| SRP064894 | KANK2 | 25959 | RNAseq | -0.2104 | 0.4809 | |
| SRP133303 | KANK2 | 25959 | RNAseq | -1.2450 | 0.0000 | |
| SRP159526 | KANK2 | 25959 | RNAseq | -0.9239 | 0.0308 | |
| SRP193095 | KANK2 | 25959 | RNAseq | 0.4096 | 0.1146 | |
| SRP219564 | KANK2 | 25959 | RNAseq | -0.3402 | 0.7199 | |
| TCGA | KANK2 | 25959 | RNAseq | -0.5029 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 4.
Survival by KANK2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KANK2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KANK2 | 25959 | 4 | 2 | 24 | |
| GSE20123 | KANK2 | 25959 | 3 | 1 | 26 | |
| GSE43470 | KANK2 | 25959 | 2 | 6 | 35 | |
| GSE46452 | KANK2 | 25959 | 47 | 1 | 11 | |
| GSE47630 | KANK2 | 25959 | 4 | 7 | 29 | |
| GSE54993 | KANK2 | 25959 | 16 | 3 | 51 | |
| GSE54994 | KANK2 | 25959 | 6 | 13 | 34 | |
| GSE60625 | KANK2 | 25959 | 9 | 0 | 2 | |
| GSE74703 | KANK2 | 25959 | 2 | 4 | 30 | |
| GSE74704 | KANK2 | 25959 | 0 | 1 | 19 | |
| TCGA | KANK2 | 25959 | 16 | 13 | 67 |
Total number of gains: 109; Total number of losses: 51; Total Number of normals: 328.
Somatic mutations of KANK2:
Generating mutation plots.
Highly correlated genes for KANK2:
Showing top 20/1008 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KANK2 | DIXDC1 | 0.875383 | 9 | 0 | 9 |
| KANK2 | ZCCHC24 | 0.86036 | 10 | 0 | 10 |
| KANK2 | ZEB1 | 0.853868 | 3 | 0 | 3 |
| KANK2 | FLNC | 0.838611 | 10 | 0 | 10 |
| KANK2 | XKR4 | 0.825527 | 5 | 0 | 5 |
| KANK2 | JAM3 | 0.823295 | 11 | 0 | 10 |
| KANK2 | KCNMA1 | 0.812207 | 9 | 0 | 8 |
| KANK2 | TBX5 | 0.803851 | 7 | 0 | 7 |
| KANK2 | MYOCD | 0.803781 | 7 | 0 | 7 |
| KANK2 | C1QTNF7 | 0.802367 | 6 | 0 | 6 |
| KANK2 | MGARP | 0.80217 | 3 | 0 | 3 |
| KANK2 | LINC01279 | 0.801928 | 4 | 0 | 4 |
| KANK2 | ILK | 0.801654 | 8 | 0 | 7 |
| KANK2 | CYP21A2 | 0.799419 | 3 | 0 | 3 |
| KANK2 | BHMT2 | 0.799408 | 9 | 0 | 8 |
| KANK2 | MSRB3 | 0.790987 | 8 | 0 | 8 |
| KANK2 | CCDC80 | 0.790582 | 7 | 0 | 7 |
| KANK2 | NLGN4X | 0.788915 | 3 | 0 | 3 |
| KANK2 | MYOC | 0.788222 | 7 | 0 | 7 |
| KANK2 | CLEC3B | 0.786016 | 3 | 0 | 3 |
For details and further investigation, click here
