| Full name: glucose-6-phosphatase catalytic subunit 3 | Alias Symbol: UGRP | ||
| Type: protein-coding gene | Cytoband: 17q21.31 | ||
| Entrez ID: 92579 | HGNC ID: HGNC:24861 | Ensembl Gene: ENSG00000141349 | OMIM ID: 611045 |
| Drug and gene relationship at DGIdb | |||
G6PC3 involved pathways:
Expression of G6PC3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | G6PC3 | 92579 | 44654_at | -0.3769 | 0.4479 | |
| GSE20347 | G6PC3 | 92579 | 44654_at | -0.0919 | 0.5891 | |
| GSE23400 | G6PC3 | 92579 | 44654_at | -0.0270 | 0.6428 | |
| GSE26886 | G6PC3 | 92579 | 44654_at | 0.6591 | 0.0007 | |
| GSE29001 | G6PC3 | 92579 | 44654_at | -0.0453 | 0.9117 | |
| GSE38129 | G6PC3 | 92579 | 44654_at | -0.0068 | 0.9699 | |
| GSE45670 | G6PC3 | 92579 | 44654_at | 0.1162 | 0.3580 | |
| GSE53622 | G6PC3 | 92579 | 13836 | 0.1797 | 0.0235 | |
| GSE53624 | G6PC3 | 92579 | 82703 | 0.3315 | 0.0006 | |
| GSE63941 | G6PC3 | 92579 | 44654_at | -0.5998 | 0.2716 | |
| GSE77861 | G6PC3 | 92579 | 44654_at | 0.1917 | 0.2979 | |
| GSE97050 | G6PC3 | 92579 | A_23_P55174 | 0.4448 | 0.2204 | |
| SRP007169 | G6PC3 | 92579 | RNAseq | -0.2806 | 0.4683 | |
| SRP008496 | G6PC3 | 92579 | RNAseq | -0.2642 | 0.4015 | |
| SRP064894 | G6PC3 | 92579 | RNAseq | 0.9765 | 0.0038 | |
| SRP133303 | G6PC3 | 92579 | RNAseq | 0.1180 | 0.4573 | |
| SRP159526 | G6PC3 | 92579 | RNAseq | 0.5507 | 0.0008 | |
| SRP193095 | G6PC3 | 92579 | RNAseq | 0.3841 | 0.0021 | |
| SRP219564 | G6PC3 | 92579 | RNAseq | -0.0243 | 0.9686 | |
| TCGA | G6PC3 | 92579 | RNAseq | -0.0787 | 0.3246 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by G6PC3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of G6PC3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | G6PC3 | 92579 | 5 | 2 | 23 | |
| GSE20123 | G6PC3 | 92579 | 5 | 2 | 23 | |
| GSE43470 | G6PC3 | 92579 | 1 | 2 | 40 | |
| GSE46452 | G6PC3 | 92579 | 32 | 0 | 27 | |
| GSE47630 | G6PC3 | 92579 | 9 | 0 | 31 | |
| GSE54993 | G6PC3 | 92579 | 3 | 4 | 63 | |
| GSE54994 | G6PC3 | 92579 | 8 | 5 | 40 | |
| GSE60625 | G6PC3 | 92579 | 4 | 0 | 7 | |
| GSE74703 | G6PC3 | 92579 | 1 | 1 | 34 | |
| GSE74704 | G6PC3 | 92579 | 3 | 1 | 16 | |
| TCGA | G6PC3 | 92579 | 23 | 7 | 66 |
Total number of gains: 94; Total number of losses: 24; Total Number of normals: 370.
Somatic mutations of G6PC3:
Generating mutation plots.
Highly correlated genes for G6PC3:
Showing top 20/328 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| G6PC3 | KLHL13 | 0.819444 | 3 | 0 | 3 |
| G6PC3 | FBXO36 | 0.747816 | 3 | 0 | 3 |
| G6PC3 | ALDOC | 0.740744 | 3 | 0 | 3 |
| G6PC3 | ZNF628 | 0.731712 | 3 | 0 | 3 |
| G6PC3 | C19orf47 | 0.717749 | 3 | 0 | 3 |
| G6PC3 | SMARCD1 | 0.71106 | 4 | 0 | 4 |
| G6PC3 | TMEM214 | 0.7108 | 4 | 0 | 4 |
| G6PC3 | ANAPC5 | 0.708207 | 3 | 0 | 3 |
| G6PC3 | FHL3 | 0.707309 | 3 | 0 | 3 |
| G6PC3 | C11orf68 | 0.699717 | 4 | 0 | 4 |
| G6PC3 | SPEN | 0.699452 | 3 | 0 | 3 |
| G6PC3 | FHOD3 | 0.699186 | 3 | 0 | 3 |
| G6PC3 | LRCH3 | 0.698233 | 4 | 0 | 3 |
| G6PC3 | EBF3 | 0.697966 | 3 | 0 | 3 |
| G6PC3 | ZNF213 | 0.695916 | 3 | 0 | 3 |
| G6PC3 | PIGS | 0.694835 | 3 | 0 | 3 |
| G6PC3 | IGF1 | 0.693257 | 3 | 0 | 3 |
| G6PC3 | SDR39U1 | 0.688009 | 3 | 0 | 3 |
| G6PC3 | POLR2A | 0.680423 | 3 | 0 | 3 |
| G6PC3 | DEPDC5 | 0.679832 | 3 | 0 | 3 |
For details and further investigation, click here
