| Full name: aldolase, fructose-bisphosphate C | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17q11.2 | ||
| Entrez ID: 230 | HGNC ID: HGNC:418 | Ensembl Gene: ENSG00000109107 | OMIM ID: 103870 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ALDOC:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ALDOC | 230 | 202022_at | -0.6759 | 0.4570 | |
| GSE20347 | ALDOC | 230 | 202022_at | -0.1827 | 0.3926 | |
| GSE23400 | ALDOC | 230 | 202022_at | -0.2753 | 0.0127 | |
| GSE26886 | ALDOC | 230 | 202022_at | -0.7059 | 0.0092 | |
| GSE29001 | ALDOC | 230 | 202022_at | -0.6430 | 0.0125 | |
| GSE38129 | ALDOC | 230 | 202022_at | -0.1351 | 0.5387 | |
| GSE45670 | ALDOC | 230 | 202022_at | 0.0401 | 0.9012 | |
| GSE53622 | ALDOC | 230 | 1918 | -0.1824 | 0.1908 | |
| GSE53624 | ALDOC | 230 | 1918 | -0.2310 | 0.0336 | |
| GSE63941 | ALDOC | 230 | 202022_at | 1.9216 | 0.0612 | |
| GSE77861 | ALDOC | 230 | 202022_at | 0.1244 | 0.6789 | |
| GSE97050 | ALDOC | 230 | A_23_P78108 | -0.0392 | 0.9277 | |
| SRP007169 | ALDOC | 230 | RNAseq | 0.2764 | 0.6948 | |
| SRP008496 | ALDOC | 230 | RNAseq | -0.1278 | 0.7807 | |
| SRP064894 | ALDOC | 230 | RNAseq | -0.4952 | 0.1425 | |
| SRP133303 | ALDOC | 230 | RNAseq | -0.0502 | 0.8658 | |
| SRP159526 | ALDOC | 230 | RNAseq | -0.0889 | 0.8677 | |
| SRP193095 | ALDOC | 230 | RNAseq | -0.7765 | 0.0010 | |
| SRP219564 | ALDOC | 230 | RNAseq | -0.2059 | 0.7573 | |
| TCGA | ALDOC | 230 | RNAseq | 0.2367 | 0.0654 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ALDOC expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ALDOC:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ALDOC | 230 | 9 | 1 | 20 | |
| GSE20123 | ALDOC | 230 | 9 | 1 | 20 | |
| GSE43470 | ALDOC | 230 | 0 | 1 | 42 | |
| GSE46452 | ALDOC | 230 | 33 | 1 | 25 | |
| GSE47630 | ALDOC | 230 | 7 | 1 | 32 | |
| GSE54993 | ALDOC | 230 | 2 | 3 | 65 | |
| GSE54994 | ALDOC | 230 | 7 | 6 | 40 | |
| GSE60625 | ALDOC | 230 | 4 | 0 | 7 | |
| GSE74703 | ALDOC | 230 | 0 | 1 | 35 | |
| GSE74704 | ALDOC | 230 | 7 | 1 | 12 | |
| TCGA | ALDOC | 230 | 21 | 10 | 65 |
Total number of gains: 99; Total number of losses: 26; Total Number of normals: 363.
Somatic mutations of ALDOC:
Generating mutation plots.
Highly correlated genes for ALDOC:
Showing top 20/302 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ALDOC | ASCC1 | 0.766077 | 3 | 0 | 3 |
| ALDOC | CCNDBP1 | 0.759752 | 3 | 0 | 3 |
| ALDOC | BRK1 | 0.758197 | 3 | 0 | 3 |
| ALDOC | ELP3 | 0.741564 | 3 | 0 | 3 |
| ALDOC | G6PC3 | 0.740744 | 3 | 0 | 3 |
| ALDOC | VPS39 | 0.739833 | 3 | 0 | 3 |
| ALDOC | PTGR1 | 0.739504 | 3 | 0 | 3 |
| ALDOC | MFAP1 | 0.731465 | 4 | 0 | 3 |
| ALDOC | CYFIP1 | 0.730839 | 4 | 0 | 4 |
| ALDOC | MAP1LC3B | 0.719627 | 3 | 0 | 3 |
| ALDOC | MRPS35 | 0.714862 | 3 | 0 | 3 |
| ALDOC | GLCE | 0.712823 | 4 | 0 | 3 |
| ALDOC | PGM1 | 0.710514 | 3 | 0 | 3 |
| ALDOC | TJP1 | 0.702663 | 4 | 0 | 4 |
| ALDOC | SNX17 | 0.689868 | 5 | 0 | 5 |
| ALDOC | SOX7 | 0.68629 | 3 | 0 | 3 |
| ALDOC | PKP2 | 0.685987 | 3 | 0 | 3 |
| ALDOC | ESYT2 | 0.684104 | 4 | 0 | 3 |
| ALDOC | ALDH1A3 | 0.683909 | 4 | 0 | 3 |
| ALDOC | PNKD | 0.682988 | 3 | 0 | 3 |
For details and further investigation, click here
