| Full name: prosaposin | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 10q22.1 | ||
| Entrez ID: 5660 | HGNC ID: HGNC:9498 | Ensembl Gene: ENSG00000197746 | OMIM ID: 176801 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of PSAP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PSAP | 5660 | 200871_s_at | 0.4087 | 0.2968 | |
| GSE20347 | PSAP | 5660 | 200871_s_at | 0.1915 | 0.1192 | |
| GSE23400 | PSAP | 5660 | 200871_s_at | 0.2500 | 0.0001 | |
| GSE26886 | PSAP | 5660 | 200871_s_at | -0.0163 | 0.9350 | |
| GSE29001 | PSAP | 5660 | 200871_s_at | 0.1579 | 0.3866 | |
| GSE38129 | PSAP | 5660 | 200871_s_at | 0.1745 | 0.1910 | |
| GSE45670 | PSAP | 5660 | 200871_s_at | 0.0943 | 0.3952 | |
| GSE53622 | PSAP | 5660 | 65859 | 0.1675 | 0.0064 | |
| GSE53624 | PSAP | 5660 | 65859 | -0.0314 | 0.7246 | |
| GSE63941 | PSAP | 5660 | 200871_s_at | -0.7139 | 0.1777 | |
| GSE77861 | PSAP | 5660 | 200871_s_at | 0.3568 | 0.1614 | |
| GSE97050 | PSAP | 5660 | A_23_P12680 | 0.3947 | 0.2237 | |
| SRP007169 | PSAP | 5660 | RNAseq | 0.0771 | 0.8849 | |
| SRP008496 | PSAP | 5660 | RNAseq | 0.1345 | 0.7087 | |
| SRP064894 | PSAP | 5660 | RNAseq | 0.7661 | 0.0005 | |
| SRP133303 | PSAP | 5660 | RNAseq | 0.6444 | 0.0006 | |
| SRP159526 | PSAP | 5660 | RNAseq | 0.6755 | 0.1068 | |
| SRP193095 | PSAP | 5660 | RNAseq | 0.2391 | 0.0539 | |
| SRP219564 | PSAP | 5660 | RNAseq | 0.7218 | 0.0546 | |
| TCGA | PSAP | 5660 | RNAseq | -0.1315 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PSAP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PSAP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PSAP | 5660 | 2 | 5 | 23 | |
| GSE20123 | PSAP | 5660 | 2 | 4 | 24 | |
| GSE43470 | PSAP | 5660 | 1 | 8 | 34 | |
| GSE46452 | PSAP | 5660 | 0 | 11 | 48 | |
| GSE47630 | PSAP | 5660 | 2 | 14 | 24 | |
| GSE54993 | PSAP | 5660 | 7 | 0 | 63 | |
| GSE54994 | PSAP | 5660 | 2 | 11 | 40 | |
| GSE60625 | PSAP | 5660 | 0 | 0 | 11 | |
| GSE74703 | PSAP | 5660 | 1 | 5 | 30 | |
| GSE74704 | PSAP | 5660 | 1 | 1 | 18 | |
| TCGA | PSAP | 5660 | 11 | 23 | 62 |
Total number of gains: 29; Total number of losses: 82; Total Number of normals: 377.
Somatic mutations of PSAP:
Generating mutation plots.
Highly correlated genes for PSAP:
Showing top 20/686 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PSAP | WDR81 | 0.81575 | 3 | 0 | 3 |
| PSAP | CLK2 | 0.777142 | 3 | 0 | 3 |
| PSAP | GALNT6 | 0.775558 | 3 | 0 | 3 |
| PSAP | GTPBP6 | 0.772414 | 3 | 0 | 3 |
| PSAP | MS4A14 | 0.754333 | 3 | 0 | 3 |
| PSAP | DHRSX | 0.749068 | 3 | 0 | 3 |
| PSAP | PDE7A | 0.748705 | 3 | 0 | 3 |
| PSAP | KRTCAP2 | 0.747863 | 3 | 0 | 3 |
| PSAP | CCDC18 | 0.744148 | 3 | 0 | 3 |
| PSAP | QSOX2 | 0.740856 | 3 | 0 | 3 |
| PSAP | PTDSS1 | 0.73884 | 3 | 0 | 3 |
| PSAP | CCDC127 | 0.734959 | 3 | 0 | 3 |
| PSAP | SSBP4 | 0.727765 | 3 | 0 | 3 |
| PSAP | PPP1R16A | 0.724549 | 3 | 0 | 3 |
| PSAP | CD96 | 0.722868 | 3 | 0 | 3 |
| PSAP | NUP210 | 0.71779 | 3 | 0 | 3 |
| PSAP | DHX37 | 0.717219 | 3 | 0 | 3 |
| PSAP | TMED8 | 0.713992 | 3 | 0 | 3 |
| PSAP | ARFRP1 | 0.711384 | 3 | 0 | 3 |
| PSAP | SYS1 | 0.709678 | 3 | 0 | 3 |
For details and further investigation, click here
