| Full name: Cdk5 and Abl enzyme substrate 2 | Alias Symbol: dJ908M14.2|ik3-2 | ||
| Type: protein-coding gene | Cytoband: 20q13.33 | ||
| Entrez ID: 81928 | HGNC ID: HGNC:16143 | Ensembl Gene: ENSG00000149679 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CABLES2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CABLES2 | 81928 | 226004_at | 0.8490 | 0.0140 | |
| GSE26886 | CABLES2 | 81928 | 226004_at | 1.1238 | 0.0002 | |
| GSE45670 | CABLES2 | 81928 | 226004_at | 0.5597 | 0.0001 | |
| GSE53622 | CABLES2 | 81928 | 75476 | 0.1986 | 0.0558 | |
| GSE53624 | CABLES2 | 81928 | 75476 | 0.5165 | 0.0000 | |
| GSE63941 | CABLES2 | 81928 | 226004_at | 1.5186 | 0.0147 | |
| GSE77861 | CABLES2 | 81928 | 226004_at | 0.2676 | 0.3735 | |
| GSE97050 | CABLES2 | 81928 | A_23_P307761 | 0.1060 | 0.6835 | |
| SRP007169 | CABLES2 | 81928 | RNAseq | 0.5740 | 0.3226 | |
| SRP008496 | CABLES2 | 81928 | RNAseq | 1.1208 | 0.0091 | |
| SRP064894 | CABLES2 | 81928 | RNAseq | 0.8291 | 0.0004 | |
| SRP133303 | CABLES2 | 81928 | RNAseq | 0.9818 | 0.0000 | |
| SRP159526 | CABLES2 | 81928 | RNAseq | 1.4595 | 0.0000 | |
| SRP193095 | CABLES2 | 81928 | RNAseq | 0.7488 | 0.0000 | |
| SRP219564 | CABLES2 | 81928 | RNAseq | 1.5627 | 0.0017 | |
| TCGA | CABLES2 | 81928 | RNAseq | 0.1479 | 0.0303 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by CABLES2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CABLES2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CABLES2 | 81928 | 13 | 2 | 15 | |
| GSE20123 | CABLES2 | 81928 | 14 | 2 | 14 | |
| GSE43470 | CABLES2 | 81928 | 11 | 1 | 31 | |
| GSE46452 | CABLES2 | 81928 | 35 | 0 | 24 | |
| GSE47630 | CABLES2 | 81928 | 25 | 1 | 14 | |
| GSE54993 | CABLES2 | 81928 | 0 | 17 | 53 | |
| GSE54994 | CABLES2 | 81928 | 29 | 0 | 24 | |
| GSE60625 | CABLES2 | 81928 | 0 | 0 | 11 | |
| GSE74703 | CABLES2 | 81928 | 10 | 0 | 26 | |
| GSE74704 | CABLES2 | 81928 | 11 | 0 | 9 | |
| TCGA | CABLES2 | 81928 | 43 | 4 | 49 |
Total number of gains: 191; Total number of losses: 27; Total Number of normals: 270.
Somatic mutations of CABLES2:
Generating mutation plots.
Highly correlated genes for CABLES2:
Showing top 20/1256 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CABLES2 | LRP8 | 0.759875 | 3 | 0 | 3 |
| CABLES2 | POFUT1 | 0.732047 | 3 | 0 | 3 |
| CABLES2 | COLGALT1 | 0.725811 | 3 | 0 | 3 |
| CABLES2 | GINS4 | 0.724267 | 3 | 0 | 3 |
| CABLES2 | C17orf67 | 0.718069 | 3 | 0 | 3 |
| CABLES2 | ERH | 0.713551 | 4 | 0 | 4 |
| CABLES2 | LSM14B | 0.709541 | 4 | 0 | 4 |
| CABLES2 | MZT1 | 0.708039 | 4 | 0 | 4 |
| CABLES2 | TGS1 | 0.706572 | 4 | 0 | 4 |
| CABLES2 | BORA | 0.706483 | 6 | 0 | 6 |
| CABLES2 | XXYLT1 | 0.705742 | 4 | 0 | 4 |
| CABLES2 | LRRC58 | 0.704707 | 4 | 0 | 3 |
| CABLES2 | GALNT6 | 0.704001 | 3 | 0 | 3 |
| CABLES2 | ELOVL7 | 0.703996 | 3 | 0 | 3 |
| CABLES2 | ADPGK | 0.703402 | 3 | 0 | 3 |
| CABLES2 | ARFGAP1 | 0.702698 | 3 | 0 | 3 |
| CABLES2 | INTS1 | 0.702505 | 4 | 0 | 4 |
| CABLES2 | NIT2 | 0.695896 | 3 | 0 | 3 |
| CABLES2 | CCT5 | 0.692813 | 4 | 0 | 4 |
| CABLES2 | ELF4 | 0.688926 | 5 | 0 | 5 |
For details and further investigation, click here
