| Full name: DnaJ heat shock protein family (Hsp40) member C4 | Alias Symbol: MCG18 | ||
| Type: protein-coding gene | Cytoband: 11q13.1 | ||
| Entrez ID: 3338 | HGNC ID: HGNC:5271 | Ensembl Gene: ENSG00000110011 | OMIM ID: 604189 |
| Drug and gene relationship at DGIdb | |||
Expression of DNAJC4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DNAJC4 | 3338 | 228622_s_at | -0.1091 | 0.7426 | |
| GSE20347 | DNAJC4 | 3338 | 206782_s_at | -0.3216 | 0.0361 | |
| GSE23400 | DNAJC4 | 3338 | 206781_at | -0.0745 | 0.0886 | |
| GSE26886 | DNAJC4 | 3338 | 228622_s_at | 0.7768 | 0.0001 | |
| GSE29001 | DNAJC4 | 3338 | 213919_at | -0.0446 | 0.8360 | |
| GSE38129 | DNAJC4 | 3338 | 206782_s_at | -0.3884 | 0.0004 | |
| GSE45670 | DNAJC4 | 3338 | 228622_s_at | -0.2587 | 0.0369 | |
| GSE53622 | DNAJC4 | 3338 | 6785 | -0.1161 | 0.0569 | |
| GSE53624 | DNAJC4 | 3338 | 6785 | -0.1813 | 0.0022 | |
| GSE63941 | DNAJC4 | 3338 | 228622_s_at | -0.4407 | 0.5251 | |
| GSE77861 | DNAJC4 | 3338 | 206781_at | -0.0388 | 0.8550 | |
| GSE97050 | DNAJC4 | 3338 | A_23_P202769 | 0.1518 | 0.4065 | |
| SRP007169 | DNAJC4 | 3338 | RNAseq | -1.1736 | 0.0120 | |
| SRP008496 | DNAJC4 | 3338 | RNAseq | -0.8996 | 0.0042 | |
| SRP064894 | DNAJC4 | 3338 | RNAseq | -0.0808 | 0.8024 | |
| SRP133303 | DNAJC4 | 3338 | RNAseq | -0.4404 | 0.0208 | |
| SRP159526 | DNAJC4 | 3338 | RNAseq | -0.3434 | 0.1052 | |
| SRP193095 | DNAJC4 | 3338 | RNAseq | -0.4197 | 0.0011 | |
| SRP219564 | DNAJC4 | 3338 | RNAseq | -0.5197 | 0.0674 | |
| TCGA | DNAJC4 | 3338 | RNAseq | -0.1825 | 0.0015 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by DNAJC4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DNAJC4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DNAJC4 | 3338 | 6 | 5 | 19 | |
| GSE20123 | DNAJC4 | 3338 | 6 | 5 | 19 | |
| GSE43470 | DNAJC4 | 3338 | 1 | 3 | 39 | |
| GSE46452 | DNAJC4 | 3338 | 8 | 4 | 47 | |
| GSE47630 | DNAJC4 | 3338 | 4 | 6 | 30 | |
| GSE54993 | DNAJC4 | 3338 | 3 | 0 | 67 | |
| GSE54994 | DNAJC4 | 3338 | 5 | 5 | 43 | |
| GSE60625 | DNAJC4 | 3338 | 0 | 4 | 7 | |
| GSE74703 | DNAJC4 | 3338 | 1 | 1 | 34 | |
| GSE74704 | DNAJC4 | 3338 | 4 | 3 | 13 | |
| TCGA | DNAJC4 | 3338 | 19 | 10 | 67 |
Total number of gains: 57; Total number of losses: 46; Total Number of normals: 385.
Somatic mutations of DNAJC4:
Generating mutation plots.
Highly correlated genes for DNAJC4:
Showing top 20/141 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DNAJC4 | NPTXR | 0.756936 | 3 | 0 | 3 |
| DNAJC4 | PKLR | 0.751988 | 3 | 0 | 3 |
| DNAJC4 | BIRC7 | 0.733173 | 3 | 0 | 3 |
| DNAJC4 | RPL36 | 0.72859 | 3 | 0 | 3 |
| DNAJC4 | TNXB | 0.710383 | 3 | 0 | 3 |
| DNAJC4 | FAM160A2 | 0.706773 | 3 | 0 | 3 |
| DNAJC4 | IZUMO4 | 0.688215 | 3 | 0 | 3 |
| DNAJC4 | GDF2 | 0.685757 | 3 | 0 | 3 |
| DNAJC4 | NCR3 | 0.682875 | 3 | 0 | 3 |
| DNAJC4 | ZNF446 | 0.680296 | 3 | 0 | 3 |
| DNAJC4 | LMAN1L | 0.679822 | 3 | 0 | 3 |
| DNAJC4 | SPPL2B | 0.676677 | 4 | 0 | 3 |
| DNAJC4 | FCN2 | 0.668363 | 3 | 0 | 3 |
| DNAJC4 | NHLH1 | 0.663487 | 3 | 0 | 3 |
| DNAJC4 | TRAPPC5 | 0.661809 | 3 | 0 | 3 |
| DNAJC4 | FAM153A | 0.660971 | 3 | 0 | 3 |
| DNAJC4 | PNMT | 0.654785 | 3 | 0 | 3 |
| DNAJC4 | DPP7 | 0.652986 | 3 | 0 | 3 |
| DNAJC4 | DEFA4 | 0.648495 | 3 | 0 | 3 |
| DNAJC4 | DPEP1 | 0.643678 | 3 | 0 | 3 |
For details and further investigation, click here
