| Full name: gem nuclear organelle associated protein 7 | Alias Symbol: FLJ13956 | ||
| Type: protein-coding gene | Cytoband: 19q13.32 | ||
| Entrez ID: 79760 | HGNC ID: HGNC:20045 | Ensembl Gene: ENSG00000142252 | OMIM ID: 607419 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of GEMIN7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GEMIN7 | 79760 | 222821_s_at | 0.2043 | 0.6545 | |
| GSE20347 | GEMIN7 | 79760 | 219085_s_at | -0.0982 | 0.2302 | |
| GSE23400 | GEMIN7 | 79760 | 219085_s_at | -0.1193 | 0.0000 | |
| GSE26886 | GEMIN7 | 79760 | 222821_s_at | 0.4575 | 0.0086 | |
| GSE29001 | GEMIN7 | 79760 | 219085_s_at | -0.1399 | 0.3443 | |
| GSE38129 | GEMIN7 | 79760 | 219085_s_at | -0.1483 | 0.0167 | |
| GSE45670 | GEMIN7 | 79760 | 222821_s_at | 0.1214 | 0.3698 | |
| GSE53622 | GEMIN7 | 79760 | 29339 | 0.2056 | 0.0191 | |
| GSE53624 | GEMIN7 | 79760 | 29339 | 0.2970 | 0.0000 | |
| GSE63941 | GEMIN7 | 79760 | 1555751_a_at | 1.0445 | 0.0235 | |
| GSE77861 | GEMIN7 | 79760 | 1555751_a_at | 0.1330 | 0.6035 | |
| GSE97050 | GEMIN7 | 79760 | A_23_P89910 | 0.4953 | 0.2096 | |
| SRP007169 | GEMIN7 | 79760 | RNAseq | -0.0559 | 0.8845 | |
| SRP008496 | GEMIN7 | 79760 | RNAseq | -0.2300 | 0.4122 | |
| SRP064894 | GEMIN7 | 79760 | RNAseq | 0.4566 | 0.1103 | |
| SRP133303 | GEMIN7 | 79760 | RNAseq | 0.2122 | 0.1994 | |
| SRP159526 | GEMIN7 | 79760 | RNAseq | 0.3545 | 0.1233 | |
| SRP193095 | GEMIN7 | 79760 | RNAseq | -0.0803 | 0.4849 | |
| SRP219564 | GEMIN7 | 79760 | RNAseq | -0.2410 | 0.5768 | |
| TCGA | GEMIN7 | 79760 | RNAseq | 0.0960 | 0.1489 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by GEMIN7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GEMIN7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GEMIN7 | 79760 | 4 | 5 | 21 | |
| GSE20123 | GEMIN7 | 79760 | 4 | 4 | 22 | |
| GSE43470 | GEMIN7 | 79760 | 3 | 11 | 29 | |
| GSE46452 | GEMIN7 | 79760 | 45 | 1 | 13 | |
| GSE47630 | GEMIN7 | 79760 | 8 | 6 | 26 | |
| GSE54993 | GEMIN7 | 79760 | 17 | 4 | 49 | |
| GSE54994 | GEMIN7 | 79760 | 6 | 12 | 35 | |
| GSE60625 | GEMIN7 | 79760 | 9 | 0 | 2 | |
| GSE74703 | GEMIN7 | 79760 | 3 | 7 | 26 | |
| GSE74704 | GEMIN7 | 79760 | 4 | 2 | 14 | |
| TCGA | GEMIN7 | 79760 | 14 | 17 | 65 |
Total number of gains: 117; Total number of losses: 69; Total Number of normals: 302.
Somatic mutations of GEMIN7:
Generating mutation plots.
Highly correlated genes for GEMIN7:
Showing top 20/618 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GEMIN7 | NR1H2 | 0.743254 | 3 | 0 | 3 |
| GEMIN7 | KTI12 | 0.739724 | 3 | 0 | 3 |
| GEMIN7 | CSF2RA | 0.729186 | 4 | 0 | 3 |
| GEMIN7 | SIRPG | 0.721631 | 3 | 0 | 3 |
| GEMIN7 | RAB35 | 0.721125 | 3 | 0 | 3 |
| GEMIN7 | HHLA1 | 0.720487 | 5 | 0 | 5 |
| GEMIN7 | B3GALT6 | 0.71571 | 3 | 0 | 3 |
| GEMIN7 | B4GALT2 | 0.71553 | 3 | 0 | 3 |
| GEMIN7 | PTPRU | 0.71248 | 3 | 0 | 3 |
| GEMIN7 | RNF187 | 0.708345 | 4 | 0 | 4 |
| GEMIN7 | FLI1 | 0.706523 | 3 | 0 | 3 |
| GEMIN7 | PSMG3 | 0.697563 | 4 | 0 | 4 |
| GEMIN7 | XXYLT1 | 0.687436 | 3 | 0 | 3 |
| GEMIN7 | HLA-DOA | 0.685941 | 6 | 0 | 6 |
| GEMIN7 | IL18BP | 0.684888 | 8 | 0 | 7 |
| GEMIN7 | PSG1 | 0.682643 | 4 | 0 | 4 |
| GEMIN7 | PNOC | 0.681619 | 3 | 0 | 3 |
| GEMIN7 | C3orf33 | 0.680601 | 3 | 0 | 3 |
| GEMIN7 | MTMR14 | 0.680061 | 3 | 0 | 3 |
| GEMIN7 | RRP36 | 0.677289 | 6 | 0 | 5 |
For details and further investigation, click here
