| Full name: myotubularin related protein 14 | Alias Symbol: FLJ22405|FLJ90311|hJumpy|hEDTP | ||
| Type: protein-coding gene | Cytoband: 3p25.3 | ||
| Entrez ID: 64419 | HGNC ID: HGNC:26190 | Ensembl Gene: ENSG00000163719 | OMIM ID: 611089 |
| Drug and gene relationship at DGIdb | |||
Expression of MTMR14:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MTMR14 | 64419 | 222143_s_at | 0.0198 | 0.9684 | |
| GSE20347 | MTMR14 | 64419 | 222143_s_at | -0.4079 | 0.0000 | |
| GSE23400 | MTMR14 | 64419 | 222143_s_at | -0.3463 | 0.0000 | |
| GSE26886 | MTMR14 | 64419 | 222143_s_at | -0.3865 | 0.0276 | |
| GSE29001 | MTMR14 | 64419 | 222143_s_at | -0.4596 | 0.0001 | |
| GSE38129 | MTMR14 | 64419 | 222143_s_at | -0.3669 | 0.0000 | |
| GSE45670 | MTMR14 | 64419 | 222143_s_at | -0.2336 | 0.0143 | |
| GSE53622 | MTMR14 | 64419 | 38964 | -0.2296 | 0.0000 | |
| GSE53624 | MTMR14 | 64419 | 38964 | -0.3910 | 0.0000 | |
| GSE63941 | MTMR14 | 64419 | 222143_s_at | 0.5879 | 0.1727 | |
| GSE77861 | MTMR14 | 64419 | 222143_s_at | -0.2589 | 0.1401 | |
| GSE97050 | MTMR14 | 64419 | A_32_P9842 | 0.2607 | 0.2385 | |
| SRP007169 | MTMR14 | 64419 | RNAseq | 0.2500 | 0.7252 | |
| SRP008496 | MTMR14 | 64419 | RNAseq | -0.3233 | 0.4665 | |
| SRP064894 | MTMR14 | 64419 | RNAseq | -0.1166 | 0.4752 | |
| SRP133303 | MTMR14 | 64419 | RNAseq | -0.4321 | 0.0000 | |
| SRP159526 | MTMR14 | 64419 | RNAseq | -0.6123 | 0.0020 | |
| SRP193095 | MTMR14 | 64419 | RNAseq | -0.5136 | 0.0000 | |
| SRP219564 | MTMR14 | 64419 | RNAseq | -0.3564 | 0.2413 | |
| TCGA | MTMR14 | 64419 | RNAseq | -0.0695 | 0.2211 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MTMR14 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MTMR14:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MTMR14 | 64419 | 1 | 18 | 11 | |
| GSE20123 | MTMR14 | 64419 | 1 | 18 | 11 | |
| GSE43470 | MTMR14 | 64419 | 1 | 20 | 22 | |
| GSE46452 | MTMR14 | 64419 | 2 | 17 | 40 | |
| GSE47630 | MTMR14 | 64419 | 3 | 22 | 15 | |
| GSE54993 | MTMR14 | 64419 | 6 | 1 | 63 | |
| GSE54994 | MTMR14 | 64419 | 3 | 31 | 19 | |
| GSE60625 | MTMR14 | 64419 | 5 | 0 | 6 | |
| GSE74703 | MTMR14 | 64419 | 1 | 16 | 19 | |
| GSE74704 | MTMR14 | 64419 | 1 | 11 | 8 | |
| TCGA | MTMR14 | 64419 | 5 | 65 | 26 |
Total number of gains: 29; Total number of losses: 219; Total Number of normals: 240.
Somatic mutations of MTMR14:
Generating mutation plots.
Highly correlated genes for MTMR14:
Showing top 20/624 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MTMR14 | SLC39A11 | 0.731994 | 4 | 0 | 4 |
| MTMR14 | GEMIN7 | 0.680061 | 3 | 0 | 3 |
| MTMR14 | REEP6 | 0.670824 | 3 | 0 | 3 |
| MTMR14 | SMPD2 | 0.659487 | 8 | 0 | 8 |
| MTMR14 | ACAA1 | 0.651402 | 7 | 0 | 6 |
| MTMR14 | TECPR1 | 0.650049 | 3 | 0 | 3 |
| MTMR14 | HLA-DOB | 0.645025 | 3 | 0 | 3 |
| MTMR14 | ARPC4 | 0.643671 | 7 | 0 | 6 |
| MTMR14 | PPFIA2 | 0.641694 | 3 | 0 | 3 |
| MTMR14 | SLC45A3 | 0.639183 | 3 | 0 | 3 |
| MTMR14 | BSPRY | 0.634244 | 8 | 0 | 6 |
| MTMR14 | PLCD1 | 0.632916 | 9 | 0 | 9 |
| MTMR14 | CNOT11 | 0.629921 | 3 | 0 | 3 |
| MTMR14 | TPRN | 0.628542 | 5 | 0 | 4 |
| MTMR14 | YTHDC2 | 0.622566 | 4 | 0 | 4 |
| MTMR14 | TICAM1 | 0.618908 | 4 | 0 | 4 |
| MTMR14 | GORASP1 | 0.618244 | 8 | 0 | 6 |
| MTMR14 | BTNL3 | 0.617096 | 3 | 0 | 3 |
| MTMR14 | UBL4B | 0.617038 | 3 | 0 | 3 |
| MTMR14 | CRBN | 0.61577 | 6 | 0 | 5 |
For details and further investigation, click here
