| Full name: rhomboid like 1 | Alias Symbol: RRP | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 9028 | HGNC ID: HGNC:10007 | Ensembl Gene: ENSG00000103269 | OMIM ID: 603264 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of RHBDL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RHBDL1 | 9028 | 207383_s_at | 0.7305 | 0.0151 | |
| GSE20347 | RHBDL1 | 9028 | 207383_s_at | 0.2595 | 0.0005 | |
| GSE23400 | RHBDL1 | 9028 | 207383_s_at | 0.1188 | 0.0017 | |
| GSE26886 | RHBDL1 | 9028 | 207383_s_at | 0.4306 | 0.0009 | |
| GSE29001 | RHBDL1 | 9028 | 207383_s_at | 0.1502 | 0.3181 | |
| GSE38129 | RHBDL1 | 9028 | 207383_s_at | 0.3046 | 0.0000 | |
| GSE45670 | RHBDL1 | 9028 | 207383_s_at | 0.2575 | 0.0027 | |
| GSE53622 | RHBDL1 | 9028 | 58375 | -0.0628 | 0.5088 | |
| GSE53624 | RHBDL1 | 9028 | 58375 | -0.1699 | 0.2644 | |
| GSE63941 | RHBDL1 | 9028 | 207383_s_at | 0.3332 | 0.4425 | |
| GSE77861 | RHBDL1 | 9028 | 207383_s_at | 0.2114 | 0.1876 | |
| GSE97050 | RHBDL1 | 9028 | A_23_P26468 | 0.0492 | 0.8143 | |
| SRP064894 | RHBDL1 | 9028 | RNAseq | 0.8621 | 0.0109 | |
| SRP133303 | RHBDL1 | 9028 | RNAseq | 0.5434 | 0.1314 | |
| SRP159526 | RHBDL1 | 9028 | RNAseq | 1.8927 | 0.0014 | |
| SRP219564 | RHBDL1 | 9028 | RNAseq | 1.0396 | 0.0710 | |
| TCGA | RHBDL1 | 9028 | RNAseq | -0.0550 | 0.8319 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by RHBDL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RHBDL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RHBDL1 | 9028 | 5 | 5 | 20 | |
| GSE20123 | RHBDL1 | 9028 | 5 | 4 | 21 | |
| GSE43470 | RHBDL1 | 9028 | 4 | 7 | 32 | |
| GSE46452 | RHBDL1 | 9028 | 38 | 1 | 20 | |
| GSE47630 | RHBDL1 | 9028 | 13 | 6 | 21 | |
| GSE54993 | RHBDL1 | 9028 | 3 | 5 | 62 | |
| GSE54994 | RHBDL1 | 9028 | 5 | 9 | 39 | |
| GSE60625 | RHBDL1 | 9028 | 4 | 0 | 7 | |
| GSE74703 | RHBDL1 | 9028 | 4 | 5 | 27 | |
| GSE74704 | RHBDL1 | 9028 | 3 | 2 | 15 | |
| TCGA | RHBDL1 | 9028 | 20 | 15 | 61 |
Total number of gains: 104; Total number of losses: 59; Total Number of normals: 325.
Somatic mutations of RHBDL1:
Generating mutation plots.
Highly correlated genes for RHBDL1:
Showing top 20/392 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RHBDL1 | GFRA4 | 0.771317 | 3 | 0 | 3 |
| RHBDL1 | LRFN1 | 0.770466 | 3 | 0 | 3 |
| RHBDL1 | OR1F1 | 0.75393 | 3 | 0 | 3 |
| RHBDL1 | TMEM52 | 0.73835 | 3 | 0 | 3 |
| RHBDL1 | TNNT2 | 0.735844 | 3 | 0 | 3 |
| RHBDL1 | GPRIN1 | 0.735471 | 3 | 0 | 3 |
| RHBDL1 | CDRT15 | 0.732047 | 3 | 0 | 3 |
| RHBDL1 | CDH2 | 0.727102 | 3 | 0 | 3 |
| RHBDL1 | RUFY4 | 0.725475 | 3 | 0 | 3 |
| RHBDL1 | ABTB1 | 0.718517 | 3 | 0 | 3 |
| RHBDL1 | CCNJL | 0.714767 | 3 | 0 | 3 |
| RHBDL1 | RTEL1 | 0.711924 | 4 | 0 | 3 |
| RHBDL1 | CDCA5 | 0.708243 | 4 | 0 | 4 |
| RHBDL1 | CRYGA | 0.70737 | 3 | 0 | 3 |
| RHBDL1 | NKX2-3 | 0.702145 | 3 | 0 | 3 |
| RHBDL1 | BCL2L12 | 0.696403 | 4 | 0 | 3 |
| RHBDL1 | ZDHHC8 | 0.694192 | 5 | 0 | 4 |
| RHBDL1 | TIGD7 | 0.693895 | 3 | 0 | 3 |
| RHBDL1 | ZMYND15 | 0.692087 | 4 | 0 | 4 |
| RHBDL1 | FAIM2 | 0.689031 | 3 | 0 | 3 |
For details and further investigation, click here
