SLC35B4

 

Full name: solute carrier family 35 member B4 Alias Symbol: FLJ14697|YEA4
Type: protein-coding gene Cytoband: 7q33
Entrez ID: 84912 HGNC ID: HGNC:20584 Ensembl Gene: ENSG00000205060 OMIM ID: 610923
Drug and gene relationship at DGIdb

 

Expression of SLC35B4:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SLC35B4 84912 225881_at 0.2361 0.6075
GSE26886 SLC35B4 84912 225881_at -0.5808 0.0460
GSE45670 SLC35B4 84912 225881_at 0.3768 0.0077
GSE53622 SLC35B4 84912 31599 -0.2734 0.0005
GSE53624 SLC35B4 84912 31599 -0.1452 0.0898
GSE63941 SLC35B4 84912 225881_at -2.1301 0.0005
GSE77861 SLC35B4 84912 225882_at 0.1557 0.2596
GSE97050 SLC35B4 84912 A_33_P3250953 -0.3709 0.3034
SRP007169 SLC35B4 84912 RNAseq 1.0191 0.0273
SRP008496 SLC35B4 84912 RNAseq 1.1165 0.0008
SRP064894 SLC35B4 84912 RNAseq 0.7012 0.0000
SRP133303 SLC35B4 84912 RNAseq 0.4761 0.0000
SRP159526 SLC35B4 84912 RNAseq 0.3944 0.0256
SRP193095 SLC35B4 84912 RNAseq 0.1901 0.0422
SRP219564 SLC35B4 84912 RNAseq 0.0927 0.7018
TCGA SLC35B4 84912 RNAseq 0.0392 0.5024

Upregulated datasets: 2; Downregulated datasets: 1.  


 

Survival by SLC35B4 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of SLC35B4:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SLC35B4 84912 6 2 22
GSE20123 SLC35B4 84912 6 2 22
GSE43470 SLC35B4 84912 2 3 38
GSE46452 SLC35B4 84912 7 2 50
GSE47630 SLC35B4 84912 7 4 29
GSE54993 SLC35B4 84912 3 5 62
GSE54994 SLC35B4 84912 6 7 40
GSE60625 SLC35B4 84912 0 0 11
GSE74703 SLC35B4 84912 2 3 31
GSE74704 SLC35B4 84912 2 2 16
TCGA SLC35B4 84912 28 23 45

Total number of gains: 69; Total number of losses: 53; Total Number of normals: 366.  


 

Somatic mutations of SLC35B4:

 

Generating mutation plots.

 

Highly correlated genes for SLC35B4:

 

Showing top 20/44 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SLC35B4LAYN0.72828303
SLC35B4ACAT20.703723303
SLC35B4YEATS20.68738303
SLC35B4GIGYF20.673535303
SLC35B4TCEAL70.66771403
SLC35B4ZC3H60.655607404
SLC35B4FAT40.653528403
SLC35B4PPM1F0.650817504
SLC35B4SIRPA0.64978403
SLC35B4ZBTB240.644395303
SLC35B4LIF0.640894303
SLC35B4ZNF5010.629889403
SLC35B4HMBS0.624711504
SLC35B4TIGD70.621569403
SLC35B4CEP190.614976403
SLC35B4PKDCC0.612795403
SLC35B4TIMMDC10.609091303
SLC35B4PPP1R12C0.608346403
SLC35B4VAMP40.602825503
SLC35B4ENOX20.602711403

For details and further investigation, click here