| Full name: GATA binding protein 2 | Alias Symbol: NFE1B | ||
| Type: protein-coding gene | Cytoband: 3q21.3 | ||
| Entrez ID: 2624 | HGNC ID: HGNC:4171 | Ensembl Gene: ENSG00000179348 | OMIM ID: 137295 |
| Drug and gene relationship at DGIdb | |||
Expression of GATA2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GATA2 | 2624 | 209710_at | -0.3311 | 0.5150 | |
| GSE20347 | GATA2 | 2624 | 210358_x_at | -0.0463 | 0.6884 | |
| GSE23400 | GATA2 | 2624 | 207954_at | -0.0935 | 0.0276 | |
| GSE26886 | GATA2 | 2624 | 209710_at | 0.1938 | 0.4217 | |
| GSE29001 | GATA2 | 2624 | 209710_at | -0.4340 | 0.4811 | |
| GSE38129 | GATA2 | 2624 | 209710_at | -0.3657 | 0.0142 | |
| GSE45670 | GATA2 | 2624 | 209710_at | -0.7367 | 0.0009 | |
| GSE53622 | GATA2 | 2624 | 45430 | -0.1828 | 0.0074 | |
| GSE53624 | GATA2 | 2624 | 45430 | -0.0158 | 0.8388 | |
| GSE63941 | GATA2 | 2624 | 209710_at | -0.0480 | 0.9419 | |
| GSE77861 | GATA2 | 2624 | 209710_at | 0.1231 | 0.3940 | |
| GSE97050 | GATA2 | 2624 | A_33_P3550894 | 0.0313 | 0.8914 | |
| SRP064894 | GATA2 | 2624 | RNAseq | -1.0534 | 0.0080 | |
| SRP133303 | GATA2 | 2624 | RNAseq | -1.3880 | 0.0000 | |
| SRP159526 | GATA2 | 2624 | RNAseq | 0.6052 | 0.2173 | |
| SRP219564 | GATA2 | 2624 | RNAseq | 0.0415 | 0.9367 | |
| TCGA | GATA2 | 2624 | RNAseq | -0.3624 | 0.0556 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by GATA2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GATA2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GATA2 | 2624 | 17 | 0 | 13 | |
| GSE20123 | GATA2 | 2624 | 17 | 0 | 13 | |
| GSE43470 | GATA2 | 2624 | 19 | 0 | 24 | |
| GSE46452 | GATA2 | 2624 | 14 | 5 | 40 | |
| GSE47630 | GATA2 | 2624 | 18 | 3 | 19 | |
| GSE54993 | GATA2 | 2624 | 2 | 7 | 61 | |
| GSE54994 | GATA2 | 2624 | 31 | 3 | 19 | |
| GSE60625 | GATA2 | 2624 | 0 | 6 | 5 | |
| GSE74703 | GATA2 | 2624 | 17 | 0 | 19 | |
| GSE74704 | GATA2 | 2624 | 13 | 0 | 7 | |
| TCGA | GATA2 | 2624 | 58 | 5 | 33 |
Total number of gains: 206; Total number of losses: 29; Total Number of normals: 253.
Somatic mutations of GATA2:
Generating mutation plots.
Highly correlated genes for GATA2:
Showing top 20/256 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GATA2 | CABP4 | 0.773798 | 3 | 0 | 3 |
| GATA2 | YY2 | 0.768982 | 3 | 0 | 3 |
| GATA2 | MYO1A | 0.752205 | 3 | 0 | 3 |
| GATA2 | PRSS38 | 0.747718 | 3 | 0 | 3 |
| GATA2 | ADAMTS7 | 0.730617 | 3 | 0 | 3 |
| GATA2 | TDRD10 | 0.73022 | 3 | 0 | 3 |
| GATA2 | IFNA4 | 0.722181 | 3 | 0 | 3 |
| GATA2 | SLC22A12 | 0.720939 | 3 | 0 | 3 |
| GATA2 | SPN | 0.717093 | 3 | 0 | 3 |
| GATA2 | VAMP4 | 0.715941 | 3 | 0 | 3 |
| GATA2 | OTOG | 0.704618 | 3 | 0 | 3 |
| GATA2 | LRSAM1 | 0.702375 | 4 | 0 | 4 |
| GATA2 | GNMT | 0.698698 | 4 | 0 | 4 |
| GATA2 | CTU1 | 0.6969 | 3 | 0 | 3 |
| GATA2 | OR10AD1 | 0.696205 | 3 | 0 | 3 |
| GATA2 | PROCA1 | 0.695088 | 3 | 0 | 3 |
| GATA2 | BBC3 | 0.694964 | 3 | 0 | 3 |
| GATA2 | WDR87 | 0.689691 | 4 | 0 | 3 |
| GATA2 | ZNF568 | 0.687856 | 3 | 0 | 3 |
| GATA2 | MFSD11 | 0.687175 | 3 | 0 | 3 |
For details and further investigation, click here
