GJB1

 

Full name: gap junction protein beta 1 Alias Symbol: CX32
Type: protein-coding gene Cytoband: Xq13.1
Entrez ID: 2705 HGNC ID: HGNC:4283 Ensembl Gene: ENSG00000169562 OMIM ID: 304040
Drug and gene relationship at DGIdb

 

Expression of GJB1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 GJB1 2705 204973_at -0.0334 0.9286
GSE20347 GJB1 2705 204973_at -0.0625 0.4364
GSE23400 GJB1 2705 204973_at -0.1261 0.0048
GSE26886 GJB1 2705 204973_at -0.0313 0.8844
GSE29001 GJB1 2705 204973_at -0.1313 0.4854
GSE38129 GJB1 2705 204973_at -0.1928 0.0447
GSE45670 GJB1 2705 204973_at 0.0490 0.6108
GSE53622 GJB1 2705 65376 -0.7727 0.0001
GSE53624 GJB1 2705 65376 -0.4439 0.0012
GSE63941 GJB1 2705 204973_at -0.0130 0.9522
GSE77861 GJB1 2705 204973_at -0.0292 0.8656
GSE97050 GJB1 2705 A_24_P404840 -0.1080 0.6171
TCGA GJB1 2705 RNAseq -3.6570 0.0000

Upregulated datasets: 0; Downregulated datasets: 1.  


 

Survival by GJB1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of GJB1:

 

No record found for this gene.


 

Somatic mutations of GJB1:

 

Generating mutation plots.

 

Highly correlated genes for GJB1:

 

Showing top 20/959 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
GJB1PSD0.740666303
GJB1AZGP10.730049303
GJB1ATP12A0.729314303
GJB1MYOG0.718799504
GJB1LRRC260.716093303
GJB1GABRR20.705795404
GJB1LTA0.701335504
GJB1IL130.700211707
GJB1PRKAR1B0.697654403
GJB1TMEM2110.686011303
GJB1PROP10.681312605
GJB1TSPAN80.680228303
GJB1SLC50A10.679536303
GJB1LINC011180.677358303
GJB1APOA50.675146303
GJB1OR10C10.674254404
GJB1ART10.671698504
GJB1SLC22A130.66971606
GJB1NOVA20.667027403
GJB1DNAH10.665238303

For details and further investigation, click here