| Full name: pleckstrin and Sec7 domain containing | Alias Symbol: KIAA2011|TYL|PSD1|EFA6A|EFA6 | ||
| Type: protein-coding gene | Cytoband: 10q24.32 | ||
| Entrez ID: 5662 | HGNC ID: HGNC:9507 | Ensembl Gene: ENSG00000059915 | OMIM ID: 602327 |
| Drug and gene relationship at DGIdb | |||
Expression of PSD:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PSD | 5662 | 208102_s_at | -0.0020 | 0.9966 | |
| GSE20347 | PSD | 5662 | 208102_s_at | -0.0490 | 0.5960 | |
| GSE23400 | PSD | 5662 | 208102_s_at | -0.0894 | 0.0214 | |
| GSE26886 | PSD | 5662 | 208102_s_at | 0.4097 | 0.0043 | |
| GSE29001 | PSD | 5662 | 208102_s_at | -0.1516 | 0.3149 | |
| GSE38129 | PSD | 5662 | 208102_s_at | -0.1340 | 0.1731 | |
| GSE45670 | PSD | 5662 | 208102_s_at | -0.0341 | 0.7534 | |
| GSE53622 | PSD | 5662 | 75870 | -0.4178 | 0.0004 | |
| GSE53624 | PSD | 5662 | 3789 | -0.5507 | 0.0000 | |
| GSE63941 | PSD | 5662 | 208102_s_at | 0.1805 | 0.1207 | |
| GSE77861 | PSD | 5662 | 208102_s_at | 0.0302 | 0.8564 | |
| GSE97050 | PSD | 5662 | A_33_P3233125 | -0.2472 | 0.3332 | |
| SRP064894 | PSD | 5662 | RNAseq | 2.9655 | 0.0000 | |
| SRP133303 | PSD | 5662 | RNAseq | 0.0187 | 0.9351 | |
| SRP193095 | PSD | 5662 | RNAseq | 0.8022 | 0.0006 | |
| SRP219564 | PSD | 5662 | RNAseq | -1.5585 | 0.3329 | |
| TCGA | PSD | 5662 | RNAseq | -0.6662 | 0.0070 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PSD expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PSD:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PSD | 5662 | 2 | 9 | 19 | |
| GSE20123 | PSD | 5662 | 2 | 8 | 20 | |
| GSE43470 | PSD | 5662 | 0 | 8 | 35 | |
| GSE46452 | PSD | 5662 | 0 | 11 | 48 | |
| GSE47630 | PSD | 5662 | 2 | 14 | 24 | |
| GSE54993 | PSD | 5662 | 8 | 0 | 62 | |
| GSE54994 | PSD | 5662 | 1 | 11 | 41 | |
| GSE60625 | PSD | 5662 | 0 | 0 | 11 | |
| GSE74703 | PSD | 5662 | 0 | 5 | 31 | |
| GSE74704 | PSD | 5662 | 1 | 4 | 15 | |
| TCGA | PSD | 5662 | 6 | 28 | 62 |
Total number of gains: 22; Total number of losses: 98; Total Number of normals: 368.
Somatic mutations of PSD:
Generating mutation plots.
Highly correlated genes for PSD:
Showing top 20/491 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PSD | JSRP1 | 0.763149 | 3 | 0 | 3 |
| PSD | MED14OS | 0.752748 | 3 | 0 | 3 |
| PSD | GJB1 | 0.740666 | 3 | 0 | 3 |
| PSD | ARVCF | 0.73724 | 5 | 0 | 5 |
| PSD | CDH15 | 0.720322 | 4 | 0 | 4 |
| PSD | KLK14 | 0.71658 | 3 | 0 | 3 |
| PSD | TCAP | 0.713892 | 4 | 0 | 4 |
| PSD | MIER2 | 0.69872 | 3 | 0 | 3 |
| PSD | CACNA1H | 0.691317 | 7 | 0 | 7 |
| PSD | NOX1 | 0.689685 | 4 | 0 | 4 |
| PSD | SP8 | 0.683894 | 3 | 0 | 3 |
| PSD | CCDC9 | 0.67634 | 3 | 0 | 3 |
| PSD | CTNNA2 | 0.673446 | 4 | 0 | 4 |
| PSD | MAPK8IP3 | 0.668419 | 4 | 0 | 4 |
| PSD | VIP | 0.667786 | 6 | 0 | 6 |
| PSD | FZR1 | 0.667654 | 3 | 0 | 3 |
| PSD | TM4SF5 | 0.667126 | 4 | 0 | 4 |
| PSD | ZNF408 | 0.666749 | 3 | 0 | 3 |
| PSD | SLN | 0.661118 | 4 | 0 | 3 |
| PSD | CCDC40 | 0.658865 | 3 | 0 | 3 |
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