| Full name: solute carrier family 50 member 1 | Alias Symbol: SCP|RP11-540D14.5|slv|RZPDo834D038D|HsSWEET1|SWEET1 | ||
| Type: protein-coding gene | Cytoband: 1q22 | ||
| Entrez ID: 55974 | HGNC ID: HGNC:30657 | Ensembl Gene: ENSG00000169241 | OMIM ID: 613683 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC50A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC50A1 | 55974 | 219125_s_at | 0.0763 | 0.8744 | |
| GSE20347 | SLC50A1 | 55974 | 219125_s_at | 0.1984 | 0.0068 | |
| GSE23400 | SLC50A1 | 55974 | 219125_s_at | 0.2352 | 0.0000 | |
| GSE26886 | SLC50A1 | 55974 | 219125_s_at | 0.0811 | 0.5589 | |
| GSE29001 | SLC50A1 | 55974 | 219125_s_at | 0.1703 | 0.4252 | |
| GSE38129 | SLC50A1 | 55974 | 219125_s_at | 0.4372 | 0.0000 | |
| GSE45670 | SLC50A1 | 55974 | 219125_s_at | 0.4138 | 0.0014 | |
| GSE53622 | SLC50A1 | 55974 | 119603 | 0.4942 | 0.0000 | |
| GSE53624 | SLC50A1 | 55974 | 119603 | 0.3499 | 0.0000 | |
| GSE63941 | SLC50A1 | 55974 | 219125_s_at | 1.1549 | 0.0188 | |
| GSE77861 | SLC50A1 | 55974 | 219125_s_at | 0.2101 | 0.3310 | |
| GSE97050 | SLC50A1 | 55974 | A_24_P88565 | 0.6910 | 0.1616 | |
| SRP007169 | SLC50A1 | 55974 | RNAseq | -0.3386 | 0.3583 | |
| SRP008496 | SLC50A1 | 55974 | RNAseq | -0.2200 | 0.3469 | |
| SRP064894 | SLC50A1 | 55974 | RNAseq | 0.4564 | 0.0335 | |
| SRP133303 | SLC50A1 | 55974 | RNAseq | 0.5366 | 0.0000 | |
| SRP159526 | SLC50A1 | 55974 | RNAseq | 0.6850 | 0.0226 | |
| SRP193095 | SLC50A1 | 55974 | RNAseq | -0.1539 | 0.3401 | |
| SRP219564 | SLC50A1 | 55974 | RNAseq | 0.4547 | 0.2317 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SLC50A1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of SLC50A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC50A1 | 55974 | 14 | 0 | 16 | |
| GSE20123 | SLC50A1 | 55974 | 13 | 0 | 17 | |
| GSE43470 | SLC50A1 | 55974 | 6 | 2 | 35 | |
| GSE46452 | SLC50A1 | 55974 | 2 | 1 | 56 | |
| GSE47630 | SLC50A1 | 55974 | 14 | 0 | 26 | |
| GSE54993 | SLC50A1 | 55974 | 0 | 4 | 66 | |
| GSE54994 | SLC50A1 | 55974 | 16 | 0 | 37 | |
| GSE60625 | SLC50A1 | 55974 | 0 | 0 | 11 | |
| GSE74703 | SLC50A1 | 55974 | 6 | 1 | 29 | |
| GSE74704 | SLC50A1 | 55974 | 6 | 0 | 14 | |
| TCGA | SLC50A1 | 55974 | 38 | 2 | 56 |
Total number of gains: 115; Total number of losses: 10; Total Number of normals: 363.
Somatic mutations of SLC50A1:
Generating mutation plots.
Highly correlated genes for SLC50A1:
Showing top 20/910 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC50A1 | SORD | 0.777675 | 4 | 0 | 4 |
| SLC50A1 | NACC1 | 0.73506 | 3 | 0 | 3 |
| SLC50A1 | TMEM167A | 0.729975 | 3 | 0 | 3 |
| SLC50A1 | AP1G1 | 0.723171 | 3 | 0 | 3 |
| SLC50A1 | FAM131B | 0.709871 | 3 | 0 | 3 |
| SLC50A1 | TBC1D2 | 0.706981 | 4 | 0 | 3 |
| SLC50A1 | KCTD11 | 0.706399 | 3 | 0 | 3 |
| SLC50A1 | TMEM54 | 0.705202 | 5 | 0 | 4 |
| SLC50A1 | KTI12 | 0.701234 | 3 | 0 | 3 |
| SLC50A1 | MOV10 | 0.696862 | 3 | 0 | 3 |
| SLC50A1 | COMTD1 | 0.692268 | 3 | 0 | 3 |
| SLC50A1 | MYO1D | 0.689507 | 4 | 0 | 3 |
| SLC50A1 | FAM89A | 0.689284 | 3 | 0 | 3 |
| SLC50A1 | MVP | 0.687152 | 4 | 0 | 3 |
| SLC50A1 | CIAPIN1 | 0.680236 | 6 | 0 | 5 |
| SLC50A1 | WNT10A | 0.679694 | 3 | 0 | 3 |
| SLC50A1 | GJB1 | 0.679536 | 3 | 0 | 3 |
| SLC50A1 | HSD17B1 | 0.678753 | 6 | 0 | 6 |
| SLC50A1 | TFAP2A | 0.678732 | 4 | 0 | 4 |
| SLC50A1 | COASY | 0.678053 | 9 | 0 | 7 |
For details and further investigation, click here
