TMEM132A

 

Full name: transmembrane protein 132A Alias Symbol: GBP|FLJ20539
Type: protein-coding gene Cytoband: 11q12.2
Entrez ID: 54972 HGNC ID: HGNC:31092 Ensembl Gene: ENSG00000006118 OMIM ID: 617363
Drug and gene relationship at DGIdb

 

Expression of TMEM132A:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TMEM132A 54972 218834_s_at 1.4262 0.0399
GSE20347 TMEM132A 54972 218834_s_at 1.2375 0.0000
GSE23400 TMEM132A 54972 218834_s_at 0.7361 0.0000
GSE26886 TMEM132A 54972 218834_s_at 1.4415 0.0000
GSE29001 TMEM132A 54972 218834_s_at 0.6307 0.0196
GSE38129 TMEM132A 54972 218834_s_at 1.3133 0.0000
GSE45670 TMEM132A 54972 218834_s_at 1.1271 0.0000
GSE63941 TMEM132A 54972 218834_s_at -0.5881 0.1674
GSE77861 TMEM132A 54972 218834_s_at 1.0693 0.0084
GSE97050 TMEM132A 54972 A_23_P24716 1.7461 0.0556
SRP007169 TMEM132A 54972 RNAseq 1.3609 0.0019
SRP008496 TMEM132A 54972 RNAseq 1.5491 0.0000
SRP064894 TMEM132A 54972 RNAseq 1.8155 0.0000
SRP133303 TMEM132A 54972 RNAseq 2.0274 0.0000
SRP159526 TMEM132A 54972 RNAseq 2.4597 0.0000
SRP193095 TMEM132A 54972 RNAseq 2.3034 0.0000
SRP219564 TMEM132A 54972 RNAseq 1.2997 0.0172
TCGA TMEM132A 54972 RNAseq 0.3227 0.0000

Upregulated datasets: 13; Downregulated datasets: 0.  


 

Survival by TMEM132A expression:

 

TCGA

 

Note: Click image to view full size file.  


Copy number change of TMEM132A:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TMEM132A 54972 2 5 23
GSE20123 TMEM132A 54972 2 5 23
GSE43470 TMEM132A 54972 2 6 35
GSE46452 TMEM132A 54972 8 4 47
GSE47630 TMEM132A 54972 3 8 29
GSE54993 TMEM132A 54972 3 0 67
GSE54994 TMEM132A 54972 5 5 43
GSE60625 TMEM132A 54972 0 3 8
GSE74703 TMEM132A 54972 2 3 31
GSE74704 TMEM132A 54972 2 3 15
TCGA TMEM132A 54972 15 10 71

Total number of gains: 44; Total number of losses: 52; Total Number of normals: 392.  


 

Somatic mutations of TMEM132A:

 

Generating mutation plots.

 

Highly correlated genes for TMEM132A:

 

Showing top 20/1641 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TMEM132AIKBIP0.811617303
TMEM132AOCIAD20.806245505
TMEM132AOAF0.797062303
TMEM132ACLPTM1L0.776049404
TMEM132AMRPL140.773636404
TMEM132ASFR10.764845303
TMEM132APDE7A0.762696505
TMEM132AFMNL20.760884505
TMEM132AUSB10.760658808
TMEM132AHAS30.759728404
TMEM132AGLIS20.759663303
TMEM132AGRAMD1A0.759394404
TMEM132AXPR10.758013505
TMEM132AB3GALT60.757213404
TMEM132AORC60.756744707
TMEM132ARAI10.755818303
TMEM132ATFRC0.755092808
TMEM132AEME10.754524504
TMEM132APLAU0.752418909
TMEM132ASLC39A30.75212404

For details and further investigation, click here