| Full name: eukaryotic translation initiation factor 5A2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3q26.2 | ||
| Entrez ID: 56648 | HGNC ID: HGNC:3301 | Ensembl Gene: ENSG00000163577 | OMIM ID: 605782 |
| Drug and gene relationship at DGIdb | |||
Expression of EIF5A2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EIF5A2 | 56648 | 235296_at | 1.7453 | 0.0469 | |
| GSE20347 | EIF5A2 | 56648 | 220198_s_at | 0.5389 | 0.0002 | |
| GSE23400 | EIF5A2 | 56648 | 220198_s_at | 0.1771 | 0.0000 | |
| GSE26886 | EIF5A2 | 56648 | 235296_at | 2.8796 | 0.0000 | |
| GSE29001 | EIF5A2 | 56648 | 220198_s_at | 0.7734 | 0.0069 | |
| GSE38129 | EIF5A2 | 56648 | 220198_s_at | 0.5865 | 0.0002 | |
| GSE45670 | EIF5A2 | 56648 | 220198_s_at | 0.8776 | 0.0071 | |
| GSE53622 | EIF5A2 | 56648 | 50465 | 0.9193 | 0.0000 | |
| GSE53624 | EIF5A2 | 56648 | 50465 | 1.3228 | 0.0000 | |
| GSE63941 | EIF5A2 | 56648 | 235296_at | -1.2032 | 0.3197 | |
| GSE77861 | EIF5A2 | 56648 | 235289_at | 0.4987 | 0.0143 | |
| GSE97050 | EIF5A2 | 56648 | A_24_P380022 | -0.0384 | 0.9029 | |
| SRP007169 | EIF5A2 | 56648 | RNAseq | 2.6447 | 0.0000 | |
| SRP008496 | EIF5A2 | 56648 | RNAseq | 3.9597 | 0.0000 | |
| SRP064894 | EIF5A2 | 56648 | RNAseq | 1.7343 | 0.0000 | |
| SRP133303 | EIF5A2 | 56648 | RNAseq | 1.5237 | 0.0000 | |
| SRP159526 | EIF5A2 | 56648 | RNAseq | 2.1250 | 0.0000 | |
| SRP193095 | EIF5A2 | 56648 | RNAseq | 1.7352 | 0.0000 | |
| SRP219564 | EIF5A2 | 56648 | RNAseq | 1.1412 | 0.0911 | |
| TCGA | EIF5A2 | 56648 | RNAseq | -0.2127 | 0.0441 |
Upregulated datasets: 9; Downregulated datasets: 0.
Survival by EIF5A2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EIF5A2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EIF5A2 | 56648 | 24 | 0 | 6 | |
| GSE20123 | EIF5A2 | 56648 | 24 | 0 | 6 | |
| GSE43470 | EIF5A2 | 56648 | 24 | 0 | 19 | |
| GSE46452 | EIF5A2 | 56648 | 19 | 1 | 39 | |
| GSE47630 | EIF5A2 | 56648 | 27 | 2 | 11 | |
| GSE54993 | EIF5A2 | 56648 | 1 | 15 | 54 | |
| GSE54994 | EIF5A2 | 56648 | 41 | 0 | 12 | |
| GSE60625 | EIF5A2 | 56648 | 0 | 6 | 5 | |
| GSE74703 | EIF5A2 | 56648 | 20 | 0 | 16 | |
| GSE74704 | EIF5A2 | 56648 | 16 | 0 | 4 | |
| TCGA | EIF5A2 | 56648 | 80 | 0 | 16 |
Total number of gains: 276; Total number of losses: 24; Total Number of normals: 188.
Somatic mutations of EIF5A2:
Generating mutation plots.
Highly correlated genes for EIF5A2:
Showing top 20/1847 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EIF5A2 | PITX2 | 0.791795 | 4 | 0 | 4 |
| EIF5A2 | A4GALT | 0.782455 | 3 | 0 | 3 |
| EIF5A2 | GGNBP2 | 0.773931 | 3 | 0 | 3 |
| EIF5A2 | SOCS7 | 0.772773 | 3 | 0 | 3 |
| EIF5A2 | GLIS2 | 0.772259 | 6 | 0 | 6 |
| EIF5A2 | RAB34 | 0.767791 | 3 | 0 | 3 |
| EIF5A2 | FADS1 | 0.760008 | 3 | 0 | 3 |
| EIF5A2 | SFT2D3 | 0.755249 | 3 | 0 | 3 |
| EIF5A2 | NR2F2 | 0.747573 | 3 | 0 | 3 |
| EIF5A2 | SLC41A1 | 0.746243 | 8 | 0 | 7 |
| EIF5A2 | DZIP3 | 0.745078 | 3 | 0 | 3 |
| EIF5A2 | AURKAIP1 | 0.744679 | 3 | 0 | 3 |
| EIF5A2 | SLC39A3 | 0.73851 | 4 | 0 | 4 |
| EIF5A2 | TMTC1 | 0.732604 | 4 | 0 | 4 |
| EIF5A2 | NEK3 | 0.730187 | 4 | 0 | 3 |
| EIF5A2 | DERL1 | 0.727116 | 3 | 0 | 3 |
| EIF5A2 | SP4 | 0.724312 | 6 | 0 | 5 |
| EIF5A2 | ALKBH6 | 0.722367 | 5 | 0 | 4 |
| EIF5A2 | CDKN1C | 0.719668 | 4 | 0 | 4 |
| EIF5A2 | PRPS1 | 0.719288 | 11 | 0 | 11 |
For details and further investigation, click here
