| Full name: MAK16 homolog | Alias Symbol: MAK16L | ||
| Type: protein-coding gene | Cytoband: 8p12 | ||
| Entrez ID: 84549 | HGNC ID: HGNC:13703 | Ensembl Gene: ENSG00000198042 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of MAK16:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MAK16 | 84549 | 211686_s_at | 0.7063 | 0.0265 | |
| GSE20347 | MAK16 | 84549 | 211686_s_at | 0.6158 | 0.0001 | |
| GSE23400 | MAK16 | 84549 | 211686_s_at | 0.5034 | 0.0000 | |
| GSE26886 | MAK16 | 84549 | 211686_s_at | 0.6619 | 0.0006 | |
| GSE29001 | MAK16 | 84549 | 211686_s_at | 0.8472 | 0.0237 | |
| GSE38129 | MAK16 | 84549 | 211686_s_at | 0.4248 | 0.0009 | |
| GSE45670 | MAK16 | 84549 | 211686_s_at | 0.2853 | 0.1517 | |
| GSE53622 | MAK16 | 84549 | 68617 | 0.3908 | 0.0000 | |
| GSE53624 | MAK16 | 84549 | 68617 | 0.5108 | 0.0000 | |
| GSE63941 | MAK16 | 84549 | 211686_s_at | -0.5555 | 0.4093 | |
| GSE77861 | MAK16 | 84549 | 211686_s_at | 0.6384 | 0.0693 | |
| GSE97050 | MAK16 | 84549 | A_23_P111961 | 0.3987 | 0.2134 | |
| SRP007169 | MAK16 | 84549 | RNAseq | 1.9651 | 0.0007 | |
| SRP008496 | MAK16 | 84549 | RNAseq | 2.0845 | 0.0000 | |
| SRP064894 | MAK16 | 84549 | RNAseq | 0.5540 | 0.0052 | |
| SRP133303 | MAK16 | 84549 | RNAseq | 0.2677 | 0.1872 | |
| SRP159526 | MAK16 | 84549 | RNAseq | 0.3688 | 0.3474 | |
| SRP193095 | MAK16 | 84549 | RNAseq | 0.3357 | 0.0223 | |
| SRP219564 | MAK16 | 84549 | RNAseq | -0.1056 | 0.7312 | |
| TCGA | MAK16 | 84549 | RNAseq | 0.0788 | 0.2320 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by MAK16 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MAK16:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MAK16 | 84549 | 4 | 10 | 16 | |
| GSE20123 | MAK16 | 84549 | 4 | 10 | 16 | |
| GSE43470 | MAK16 | 84549 | 4 | 7 | 32 | |
| GSE46452 | MAK16 | 84549 | 15 | 11 | 33 | |
| GSE47630 | MAK16 | 84549 | 10 | 8 | 22 | |
| GSE54993 | MAK16 | 84549 | 2 | 16 | 52 | |
| GSE54994 | MAK16 | 84549 | 11 | 16 | 26 | |
| GSE60625 | MAK16 | 84549 | 3 | 0 | 8 | |
| GSE74703 | MAK16 | 84549 | 4 | 6 | 26 | |
| GSE74704 | MAK16 | 84549 | 3 | 6 | 11 | |
| TCGA | MAK16 | 84549 | 24 | 33 | 39 |
Total number of gains: 84; Total number of losses: 123; Total Number of normals: 281.
Somatic mutations of MAK16:
Generating mutation plots.
Highly correlated genes for MAK16:
Showing top 20/1646 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MAK16 | CASC4 | 0.813036 | 3 | 0 | 3 |
| MAK16 | ZBTB34 | 0.779198 | 3 | 0 | 3 |
| MAK16 | ZNF791 | 0.772681 | 3 | 0 | 3 |
| MAK16 | PGAP1 | 0.766669 | 3 | 0 | 3 |
| MAK16 | RHOBTB3 | 0.762674 | 3 | 0 | 3 |
| MAK16 | NAPEPLD | 0.762536 | 4 | 0 | 4 |
| MAK16 | CISD2 | 0.760053 | 3 | 0 | 3 |
| MAK16 | RNASEH2B | 0.759192 | 3 | 0 | 3 |
| MAK16 | GLIS2 | 0.758882 | 3 | 0 | 3 |
| MAK16 | GLI3 | 0.753909 | 3 | 0 | 3 |
| MAK16 | MOB3C | 0.753031 | 3 | 0 | 3 |
| MAK16 | HSDL1 | 0.746975 | 3 | 0 | 3 |
| MAK16 | NTPCR | 0.746139 | 3 | 0 | 3 |
| MAK16 | PKIG | 0.743545 | 3 | 0 | 3 |
| MAK16 | RBPJ | 0.741764 | 3 | 0 | 3 |
| MAK16 | FAM161A | 0.73993 | 4 | 0 | 3 |
| MAK16 | RALGAPB | 0.738454 | 3 | 0 | 3 |
| MAK16 | WRN | 0.736402 | 12 | 0 | 12 |
| MAK16 | E4F1 | 0.734575 | 3 | 0 | 3 |
| MAK16 | MRPS6 | 0.734475 | 3 | 0 | 3 |
For details and further investigation, click here
