| Full name: tRNA methyltransferase 2 homolog A | Alias Symbol: HTF9C | ||
| Type: protein-coding gene | Cytoband: 22q11.21 | ||
| Entrez ID: 27037 | HGNC ID: HGNC:24974 | Ensembl Gene: ENSG00000099899 | OMIM ID: 611151 |
| Drug and gene relationship at DGIdb | |||
Expression of TRMT2A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRMT2A | 27037 | 218475_at | 0.4500 | 0.1154 | |
| GSE20347 | TRMT2A | 27037 | 218475_at | 0.0544 | 0.5451 | |
| GSE23400 | TRMT2A | 27037 | 218475_at | 0.0447 | 0.2423 | |
| GSE26886 | TRMT2A | 27037 | 218475_at | 0.1915 | 0.1514 | |
| GSE29001 | TRMT2A | 27037 | 218475_at | -0.0244 | 0.8628 | |
| GSE38129 | TRMT2A | 27037 | 218475_at | 0.0974 | 0.2347 | |
| GSE45670 | TRMT2A | 27037 | 218475_at | 0.2151 | 0.0131 | |
| GSE53622 | TRMT2A | 27037 | 84825 | 0.2558 | 0.0015 | |
| GSE53624 | TRMT2A | 27037 | 84825 | 0.3373 | 0.0000 | |
| GSE63941 | TRMT2A | 27037 | 218475_at | 0.4292 | 0.0559 | |
| GSE77861 | TRMT2A | 27037 | 218475_at | 0.1767 | 0.1679 | |
| GSE97050 | TRMT2A | 27037 | A_24_P305662 | 0.1394 | 0.5925 | |
| SRP007169 | TRMT2A | 27037 | RNAseq | 0.5331 | 0.2222 | |
| SRP008496 | TRMT2A | 27037 | RNAseq | 0.1060 | 0.7429 | |
| SRP064894 | TRMT2A | 27037 | RNAseq | 0.7238 | 0.0015 | |
| SRP133303 | TRMT2A | 27037 | RNAseq | -0.0193 | 0.8818 | |
| SRP159526 | TRMT2A | 27037 | RNAseq | 0.2105 | 0.3503 | |
| SRP193095 | TRMT2A | 27037 | RNAseq | 0.3401 | 0.0027 | |
| SRP219564 | TRMT2A | 27037 | RNAseq | 0.4323 | 0.1839 | |
| TCGA | TRMT2A | 27037 | RNAseq | 0.1257 | 0.0303 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TRMT2A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRMT2A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRMT2A | 27037 | 5 | 7 | 18 | |
| GSE20123 | TRMT2A | 27037 | 5 | 7 | 18 | |
| GSE43470 | TRMT2A | 27037 | 4 | 7 | 32 | |
| GSE46452 | TRMT2A | 27037 | 33 | 1 | 25 | |
| GSE47630 | TRMT2A | 27037 | 8 | 5 | 27 | |
| GSE54993 | TRMT2A | 27037 | 3 | 6 | 61 | |
| GSE54994 | TRMT2A | 27037 | 12 | 7 | 34 | |
| GSE60625 | TRMT2A | 27037 | 5 | 0 | 6 | |
| GSE74703 | TRMT2A | 27037 | 4 | 5 | 27 | |
| GSE74704 | TRMT2A | 27037 | 3 | 4 | 13 | |
| TCGA | TRMT2A | 27037 | 27 | 17 | 52 |
Total number of gains: 109; Total number of losses: 66; Total Number of normals: 313.
Somatic mutations of TRMT2A:
Generating mutation plots.
Highly correlated genes for TRMT2A:
Showing top 20/566 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRMT2A | SHANK3 | 0.739208 | 3 | 0 | 3 |
| TRMT2A | NONO | 0.7378 | 3 | 0 | 3 |
| TRMT2A | FTSJ3 | 0.73534 | 3 | 0 | 3 |
| TRMT2A | ATR | 0.735064 | 3 | 0 | 3 |
| TRMT2A | OAF | 0.732512 | 3 | 0 | 3 |
| TRMT2A | ZC3HC1 | 0.728493 | 3 | 0 | 3 |
| TRMT2A | GART | 0.721859 | 3 | 0 | 3 |
| TRMT2A | BYSL | 0.718305 | 3 | 0 | 3 |
| TRMT2A | TMEM63B | 0.715418 | 4 | 0 | 3 |
| TRMT2A | DROSHA | 0.705051 | 3 | 0 | 3 |
| TRMT2A | IGF2R | 0.703911 | 4 | 0 | 4 |
| TRMT2A | TRPC4AP | 0.702385 | 3 | 0 | 3 |
| TRMT2A | LYRM4 | 0.701629 | 3 | 0 | 3 |
| TRMT2A | HHAT | 0.699057 | 3 | 0 | 3 |
| TRMT2A | DHX33 | 0.697933 | 4 | 0 | 4 |
| TRMT2A | TRIM59 | 0.695185 | 3 | 0 | 3 |
| TRMT2A | U2SURP | 0.6942 | 3 | 0 | 3 |
| TRMT2A | DOCK6 | 0.691864 | 4 | 0 | 4 |
| TRMT2A | CCDC58 | 0.690515 | 3 | 0 | 3 |
| TRMT2A | GOLGA8A | 0.687973 | 3 | 0 | 3 |
For details and further investigation, click here
