GORASP1

 

Full name: golgi reassembly stacking protein 1 Alias Symbol: GRASP65|P65|FLJ23443
Type: protein-coding gene Cytoband: 3p22.2
Entrez ID: 64689 HGNC ID: HGNC:16769 Ensembl Gene: ENSG00000114745 OMIM ID: 606867
Drug and gene relationship at DGIdb
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of GORASP1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 GORASP1 64689 215749_s_at -0.1879 0.6731
GSE20347 GORASP1 64689 215749_s_at -0.6627 0.0000
GSE23400 GORASP1 64689 215749_s_at -0.4163 0.0000
GSE26886 GORASP1 64689 215749_s_at -0.8408 0.0000
GSE29001 GORASP1 64689 215749_s_at -0.7246 0.0008
GSE38129 GORASP1 64689 215749_s_at -0.6903 0.0000
GSE45670 GORASP1 64689 215749_s_at -0.1649 0.1787
GSE53622 GORASP1 64689 69721 -0.5169 0.0000
GSE53624 GORASP1 64689 3165 -0.7506 0.0000
GSE63941 GORASP1 64689 215749_s_at -0.3774 0.1987
GSE77861 GORASP1 64689 215749_s_at -0.5640 0.0019
GSE97050 GORASP1 64689 A_23_P427114 -0.5077 0.0899
SRP007169 GORASP1 64689 RNAseq -1.1278 0.0237
SRP008496 GORASP1 64689 RNAseq -0.9502 0.0052
SRP064894 GORASP1 64689 RNAseq -0.5313 0.0000
SRP133303 GORASP1 64689 RNAseq -0.6314 0.0000
SRP159526 GORASP1 64689 RNAseq -0.9967 0.0000
SRP193095 GORASP1 64689 RNAseq -0.6588 0.0000
SRP219564 GORASP1 64689 RNAseq -0.6143 0.0482
TCGA GORASP1 64689 RNAseq -0.2846 0.0000

Upregulated datasets: 0; Downregulated datasets: 1.  


 

Survival by GORASP1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of GORASP1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 GORASP1 64689 0 19 11
GSE20123 GORASP1 64689 0 19 11
GSE43470 GORASP1 64689 0 20 23
GSE46452 GORASP1 64689 2 17 40
GSE47630 GORASP1 64689 1 25 14
GSE54993 GORASP1 64689 7 2 61
GSE54994 GORASP1 64689 0 34 19
GSE60625 GORASP1 64689 5 0 6
GSE74703 GORASP1 64689 0 16 20
GSE74704 GORASP1 64689 0 13 7
TCGA GORASP1 64689 1 71 24

Total number of gains: 16; Total number of losses: 236; Total Number of normals: 236.  


 

Somatic mutations of GORASP1:

 

Generating mutation plots.

 

Highly correlated genes for GORASP1:

 

Showing top 20/1400 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
GORASP1ADCK10.829512303
GORASP1ZNF2230.819518303
GORASP1UBXN10.791831303
GORASP1LRRFIP20.76488210010
GORASP1TSTA30.761238303
GORASP1ZBTB220.753083303
GORASP1ANO100.74241710010
GORASP1PRKAR2A0.734707
GORASP1ZNF1430.728143303
GORASP1SFTA20.728085303
GORASP1MPP70.725815606
GORASP1RAB5A0.72469210010
GORASP1GPD1L0.72263712011
GORASP1ARL2BP0.722366303
GORASP1DCAF80.722105303
GORASP1ACVR2A0.721488403
GORASP1GOLGA40.719063808
GORASP1GGA30.717645504
GORASP1CRYL10.7159910010
GORASP1KAT2B0.71540511010

For details and further investigation, click here