| Full name: LRR binding FLII interacting protein 2 | Alias Symbol: HUFI-2 | ||
| Type: protein-coding gene | Cytoband: 3p22.2 | ||
| Entrez ID: 9209 | HGNC ID: HGNC:6703 | Ensembl Gene: ENSG00000093167 | OMIM ID: 614043 |
| Drug and gene relationship at DGIdb | |||
Expression of LRRFIP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRRFIP2 | 9209 | 218364_at | -1.0281 | 0.0640 | |
| GSE20347 | LRRFIP2 | 9209 | 218364_at | -1.7946 | 0.0000 | |
| GSE23400 | LRRFIP2 | 9209 | 218364_at | -1.1616 | 0.0000 | |
| GSE26886 | LRRFIP2 | 9209 | 218364_at | -1.4442 | 0.0000 | |
| GSE29001 | LRRFIP2 | 9209 | 218364_at | -1.6486 | 0.0000 | |
| GSE38129 | LRRFIP2 | 9209 | 218364_at | -1.4395 | 0.0000 | |
| GSE45670 | LRRFIP2 | 9209 | 218364_at | -0.9337 | 0.0000 | |
| GSE53622 | LRRFIP2 | 9209 | 6184 | -1.2940 | 0.0000 | |
| GSE53624 | LRRFIP2 | 9209 | 6184 | -1.4783 | 0.0000 | |
| GSE63941 | LRRFIP2 | 9209 | 218364_at | -1.2737 | 0.0069 | |
| GSE77861 | LRRFIP2 | 9209 | 220610_s_at | -0.7358 | 0.0065 | |
| GSE97050 | LRRFIP2 | 9209 | A_23_P317184 | -0.9118 | 0.0726 | |
| SRP007169 | LRRFIP2 | 9209 | RNAseq | -2.3813 | 0.0000 | |
| SRP008496 | LRRFIP2 | 9209 | RNAseq | -2.2840 | 0.0000 | |
| SRP064894 | LRRFIP2 | 9209 | RNAseq | -1.6082 | 0.0000 | |
| SRP133303 | LRRFIP2 | 9209 | RNAseq | -1.0855 | 0.0000 | |
| SRP159526 | LRRFIP2 | 9209 | RNAseq | -1.3987 | 0.0000 | |
| SRP193095 | LRRFIP2 | 9209 | RNAseq | -1.1678 | 0.0000 | |
| SRP219564 | LRRFIP2 | 9209 | RNAseq | -1.4784 | 0.0000 | |
| TCGA | LRRFIP2 | 9209 | RNAseq | -0.2244 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 15.
Survival by LRRFIP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRRFIP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRRFIP2 | 9209 | 0 | 18 | 12 | |
| GSE20123 | LRRFIP2 | 9209 | 0 | 18 | 12 | |
| GSE43470 | LRRFIP2 | 9209 | 0 | 20 | 23 | |
| GSE46452 | LRRFIP2 | 9209 | 2 | 17 | 40 | |
| GSE47630 | LRRFIP2 | 9209 | 1 | 25 | 14 | |
| GSE54993 | LRRFIP2 | 9209 | 6 | 3 | 61 | |
| GSE54994 | LRRFIP2 | 9209 | 1 | 32 | 20 | |
| GSE60625 | LRRFIP2 | 9209 | 5 | 0 | 6 | |
| GSE74703 | LRRFIP2 | 9209 | 0 | 16 | 20 | |
| GSE74704 | LRRFIP2 | 9209 | 0 | 12 | 8 | |
| TCGA | LRRFIP2 | 9209 | 0 | 71 | 25 |
Total number of gains: 15; Total number of losses: 232; Total Number of normals: 241.
Somatic mutations of LRRFIP2:
Generating mutation plots.
Highly correlated genes for LRRFIP2:
Showing top 20/1671 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRRFIP2 | GYS2 | 0.848695 | 10 | 0 | 10 |
| LRRFIP2 | UBL3 | 0.841274 | 10 | 0 | 10 |
| LRRFIP2 | RMND5B | 0.838554 | 11 | 0 | 11 |
| LRRFIP2 | KRT78 | 0.83581 | 6 | 0 | 6 |
| LRRFIP2 | FCHO2 | 0.828678 | 7 | 0 | 7 |
| LRRFIP2 | EPB41L3 | 0.824675 | 11 | 0 | 11 |
| LRRFIP2 | SLC46A2 | 0.82311 | 7 | 0 | 7 |
| LRRFIP2 | BNIPL | 0.822616 | 6 | 0 | 6 |
| LRRFIP2 | RANBP9 | 0.821961 | 11 | 0 | 11 |
| LRRFIP2 | RAB5A | 0.819187 | 13 | 0 | 12 |
| LRRFIP2 | PHACTR2 | 0.818675 | 10 | 0 | 10 |
| LRRFIP2 | DHRS1 | 0.818163 | 10 | 0 | 10 |
| LRRFIP2 | TMOD3 | 0.816567 | 10 | 0 | 10 |
| LRRFIP2 | KAT2B | 0.816428 | 12 | 0 | 12 |
| LRRFIP2 | ECM1 | 0.814396 | 11 | 0 | 11 |
| LRRFIP2 | ANO10 | 0.814189 | 11 | 0 | 11 |
| LRRFIP2 | KCTD6 | 0.810197 | 7 | 0 | 7 |
| LRRFIP2 | GOLGA4 | 0.80912 | 10 | 0 | 10 |
| LRRFIP2 | SLC16A6 | 0.808182 | 12 | 0 | 12 |
| LRRFIP2 | CWH43 | 0.80792 | 10 | 0 | 10 |
For details and further investigation, click here
