| Full name: DDB1 and CUL4 associated factor 8 | Alias Symbol: H326|FLJ35857 | ||
| Type: protein-coding gene | Cytoband: 1q23.2 | ||
| Entrez ID: 50717 | HGNC ID: HGNC:24891 | Ensembl Gene: ENSG00000132716 | OMIM ID: 615820 |
| Drug and gene relationship at DGIdb | |||
Expression of DCAF8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DCAF8 | 50717 | 202249_s_at | 0.0064 | 0.9889 | |
| GSE20347 | DCAF8 | 50717 | 202249_s_at | 0.1163 | 0.2483 | |
| GSE23400 | DCAF8 | 50717 | 216885_s_at | -0.0971 | 0.0256 | |
| GSE26886 | DCAF8 | 50717 | 243318_at | -0.4985 | 0.0337 | |
| GSE29001 | DCAF8 | 50717 | 202250_s_at | 0.0862 | 0.7793 | |
| GSE38129 | DCAF8 | 50717 | 202250_s_at | -0.4943 | 0.0100 | |
| GSE45670 | DCAF8 | 50717 | 202249_s_at | -0.0431 | 0.7331 | |
| GSE53622 | DCAF8 | 50717 | 8261 | -0.4672 | 0.0000 | |
| GSE53624 | DCAF8 | 50717 | 39144 | -0.1023 | 0.1395 | |
| GSE63941 | DCAF8 | 50717 | 243318_at | 0.6408 | 0.1374 | |
| GSE77861 | DCAF8 | 50717 | 202249_s_at | 0.1179 | 0.4570 | |
| GSE97050 | DCAF8 | 50717 | A_23_P200143 | -0.5455 | 0.3269 | |
| SRP007169 | DCAF8 | 50717 | RNAseq | -0.6558 | 0.0215 | |
| SRP008496 | DCAF8 | 50717 | RNAseq | -0.3540 | 0.0332 | |
| SRP064894 | DCAF8 | 50717 | RNAseq | -0.0503 | 0.5049 | |
| SRP133303 | DCAF8 | 50717 | RNAseq | -0.0835 | 0.5768 | |
| SRP159526 | DCAF8 | 50717 | RNAseq | 0.2068 | 0.3838 | |
| SRP193095 | DCAF8 | 50717 | RNAseq | 0.1211 | 0.2209 | |
| SRP219564 | DCAF8 | 50717 | RNAseq | -0.1324 | 0.7199 | |
| TCGA | DCAF8 | 50717 | RNAseq | -0.1717 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DCAF8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DCAF8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DCAF8 | 50717 | 10 | 0 | 20 | |
| GSE20123 | DCAF8 | 50717 | 10 | 0 | 20 | |
| GSE43470 | DCAF8 | 50717 | 7 | 2 | 34 | |
| GSE46452 | DCAF8 | 50717 | 2 | 1 | 56 | |
| GSE47630 | DCAF8 | 50717 | 15 | 0 | 25 | |
| GSE54993 | DCAF8 | 50717 | 0 | 5 | 65 | |
| GSE54994 | DCAF8 | 50717 | 16 | 0 | 37 | |
| GSE60625 | DCAF8 | 50717 | 0 | 0 | 11 | |
| GSE74703 | DCAF8 | 50717 | 7 | 2 | 27 | |
| GSE74704 | DCAF8 | 50717 | 4 | 0 | 16 | |
| TCGA | DCAF8 | 50717 | 44 | 3 | 49 |
Total number of gains: 115; Total number of losses: 13; Total Number of normals: 360.
Somatic mutations of DCAF8:
Generating mutation plots.
Highly correlated genes for DCAF8:
Showing top 20/249 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DCAF8 | MOAP1 | 0.754162 | 4 | 0 | 4 |
| DCAF8 | RNASE4 | 0.748262 | 3 | 0 | 3 |
| DCAF8 | C7 | 0.748059 | 3 | 0 | 3 |
| DCAF8 | GORASP1 | 0.722105 | 3 | 0 | 3 |
| DCAF8 | FBXO9 | 0.72151 | 4 | 0 | 4 |
| DCAF8 | DMD | 0.720216 | 3 | 0 | 3 |
| DCAF8 | GGN | 0.719305 | 3 | 0 | 3 |
| DCAF8 | DNAJA2 | 0.718447 | 3 | 0 | 3 |
| DCAF8 | EZH1 | 0.711677 | 5 | 0 | 4 |
| DCAF8 | NUFIP2 | 0.707526 | 3 | 0 | 3 |
| DCAF8 | STX17 | 0.707331 | 4 | 0 | 4 |
| DCAF8 | CSNK1D | 0.706278 | 4 | 0 | 4 |
| DCAF8 | KLHDC8B | 0.706077 | 3 | 0 | 3 |
| DCAF8 | OSBPL2 | 0.705055 | 3 | 0 | 3 |
| DCAF8 | COCH | 0.703891 | 3 | 0 | 3 |
| DCAF8 | SH3BGR | 0.701177 | 3 | 0 | 3 |
| DCAF8 | SORBS2 | 0.7001 | 3 | 0 | 3 |
| DCAF8 | DAG1 | 0.6985 | 3 | 0 | 3 |
| DCAF8 | SPOP | 0.696976 | 5 | 0 | 4 |
| DCAF8 | SYNM | 0.694269 | 3 | 0 | 3 |
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