| Full name: zinc finger protein 143 | Alias Symbol: SBF|pHZ-1|STAF | ||
| Type: protein-coding gene | Cytoband: 11p15.4 | ||
| Entrez ID: 7702 | HGNC ID: HGNC:12928 | Ensembl Gene: ENSG00000166478 | OMIM ID: 603433 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ZNF143:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF143 | 7702 | 221873_at | -0.2186 | 0.4519 | |
| GSE20347 | ZNF143 | 7702 | 221873_at | -0.4388 | 0.0002 | |
| GSE23400 | ZNF143 | 7702 | 221873_at | -0.0457 | 0.3026 | |
| GSE26886 | ZNF143 | 7702 | 221873_at | -0.1430 | 0.4122 | |
| GSE29001 | ZNF143 | 7702 | 221873_at | -0.1707 | 0.3395 | |
| GSE38129 | ZNF143 | 7702 | 221873_at | -0.3559 | 0.0001 | |
| GSE45670 | ZNF143 | 7702 | 221873_at | -0.1135 | 0.2804 | |
| GSE53622 | ZNF143 | 7702 | 4628 | -0.0833 | 0.2560 | |
| GSE53624 | ZNF143 | 7702 | 4628 | 0.0038 | 0.9555 | |
| GSE63941 | ZNF143 | 7702 | 221873_at | -0.0352 | 0.9425 | |
| GSE77861 | ZNF143 | 7702 | 221873_at | -0.1199 | 0.5336 | |
| GSE97050 | ZNF143 | 7702 | A_24_P206736 | -0.1514 | 0.5845 | |
| SRP007169 | ZNF143 | 7702 | RNAseq | 0.2735 | 0.5894 | |
| SRP008496 | ZNF143 | 7702 | RNAseq | 0.2588 | 0.4819 | |
| SRP064894 | ZNF143 | 7702 | RNAseq | -0.3361 | 0.0377 | |
| SRP133303 | ZNF143 | 7702 | RNAseq | 0.0467 | 0.6617 | |
| SRP159526 | ZNF143 | 7702 | RNAseq | -0.4194 | 0.0830 | |
| SRP193095 | ZNF143 | 7702 | RNAseq | -0.2331 | 0.0043 | |
| SRP219564 | ZNF143 | 7702 | RNAseq | -0.3866 | 0.1464 | |
| TCGA | ZNF143 | 7702 | RNAseq | 0.0220 | 0.6956 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZNF143 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF143:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF143 | 7702 | 0 | 9 | 21 | |
| GSE20123 | ZNF143 | 7702 | 0 | 9 | 21 | |
| GSE43470 | ZNF143 | 7702 | 1 | 6 | 36 | |
| GSE46452 | ZNF143 | 7702 | 7 | 5 | 47 | |
| GSE47630 | ZNF143 | 7702 | 3 | 11 | 26 | |
| GSE54993 | ZNF143 | 7702 | 3 | 1 | 66 | |
| GSE54994 | ZNF143 | 7702 | 2 | 15 | 36 | |
| GSE60625 | ZNF143 | 7702 | 0 | 0 | 11 | |
| GSE74703 | ZNF143 | 7702 | 1 | 4 | 31 | |
| GSE74704 | ZNF143 | 7702 | 0 | 7 | 13 | |
| TCGA | ZNF143 | 7702 | 11 | 34 | 51 |
Total number of gains: 28; Total number of losses: 101; Total Number of normals: 359.
Somatic mutations of ZNF143:
Generating mutation plots.
Highly correlated genes for ZNF143:
Showing top 20/391 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF143 | TMOD2 | 0.767554 | 3 | 0 | 3 |
| ZNF143 | RASGEF1B | 0.748792 | 3 | 0 | 3 |
| ZNF143 | ZNF268 | 0.741082 | 3 | 0 | 3 |
| ZNF143 | SEC16B | 0.735461 | 3 | 0 | 3 |
| ZNF143 | PINK1 | 0.732099 | 4 | 0 | 4 |
| ZNF143 | GORASP1 | 0.728143 | 3 | 0 | 3 |
| ZNF143 | ANKMY2 | 0.72583 | 3 | 0 | 3 |
| ZNF143 | ABCG2 | 0.725352 | 3 | 0 | 3 |
| ZNF143 | UBQLN2 | 0.7178 | 3 | 0 | 3 |
| ZNF143 | PLK3 | 0.712428 | 3 | 0 | 3 |
| ZNF143 | CCDC6 | 0.708063 | 3 | 0 | 3 |
| ZNF143 | MALT1 | 0.697387 | 4 | 0 | 4 |
| ZNF143 | NR2C2 | 0.696565 | 3 | 0 | 3 |
| ZNF143 | CASP9 | 0.693492 | 3 | 0 | 3 |
| ZNF143 | AMOTL2 | 0.692479 | 4 | 0 | 4 |
| ZNF143 | XPO4 | 0.689704 | 3 | 0 | 3 |
| ZNF143 | MIER3 | 0.684001 | 4 | 0 | 3 |
| ZNF143 | MAPK7 | 0.683564 | 3 | 0 | 3 |
| ZNF143 | TXNL1 | 0.683563 | 4 | 0 | 4 |
| ZNF143 | ATL1 | 0.678407 | 3 | 0 | 3 |
For details and further investigation, click here
