| Full name: golgi SNAP receptor complex member 2 | Alias Symbol: GS27|Bos1 | ||
| Type: protein-coding gene | Cytoband: 17q21.32 | ||
| Entrez ID: 9570 | HGNC ID: HGNC:4431 | Ensembl Gene: ENSG00000108433 | OMIM ID: 604027 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of GOSR2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GOSR2 | 9570 | 235041_at | 0.2411 | 0.4387 | |
| GSE20347 | GOSR2 | 9570 | 213144_at | -0.0250 | 0.8073 | |
| GSE23400 | GOSR2 | 9570 | 213180_s_at | 0.1632 | 0.0015 | |
| GSE26886 | GOSR2 | 9570 | 235041_at | 0.5765 | 0.0034 | |
| GSE29001 | GOSR2 | 9570 | 213144_at | 0.1755 | 0.2707 | |
| GSE38129 | GOSR2 | 9570 | 213144_at | 0.0116 | 0.9046 | |
| GSE45670 | GOSR2 | 9570 | 235041_at | 0.1425 | 0.1947 | |
| GSE53622 | GOSR2 | 9570 | 40389 | 0.3307 | 0.0000 | |
| GSE53624 | GOSR2 | 9570 | 40389 | 0.5366 | 0.0000 | |
| GSE63941 | GOSR2 | 9570 | 235041_at | 0.0619 | 0.8166 | |
| GSE77861 | GOSR2 | 9570 | 235041_at | 0.2501 | 0.1022 | |
| GSE97050 | GOSR2 | 9570 | A_24_P108242 | -0.0378 | 0.9011 | |
| SRP007169 | GOSR2 | 9570 | RNAseq | -0.2587 | 0.4643 | |
| SRP008496 | GOSR2 | 9570 | RNAseq | -0.2972 | 0.1952 | |
| SRP064894 | GOSR2 | 9570 | RNAseq | 0.2367 | 0.0453 | |
| SRP133303 | GOSR2 | 9570 | RNAseq | 0.0803 | 0.3771 | |
| SRP159526 | GOSR2 | 9570 | RNAseq | 0.1320 | 0.4815 | |
| SRP193095 | GOSR2 | 9570 | RNAseq | -0.0997 | 0.3236 | |
| SRP219564 | GOSR2 | 9570 | RNAseq | 0.2221 | 0.4659 | |
| TCGA | GOSR2 | 9570 | RNAseq | -0.0992 | 0.0372 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GOSR2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GOSR2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GOSR2 | 9570 | 5 | 2 | 23 | |
| GSE20123 | GOSR2 | 9570 | 5 | 2 | 23 | |
| GSE43470 | GOSR2 | 9570 | 1 | 2 | 40 | |
| GSE46452 | GOSR2 | 9570 | 32 | 0 | 27 | |
| GSE47630 | GOSR2 | 9570 | 9 | 0 | 31 | |
| GSE54993 | GOSR2 | 9570 | 2 | 4 | 64 | |
| GSE54994 | GOSR2 | 9570 | 11 | 5 | 37 | |
| GSE60625 | GOSR2 | 9570 | 4 | 0 | 7 | |
| GSE74703 | GOSR2 | 9570 | 1 | 1 | 34 | |
| GSE74704 | GOSR2 | 9570 | 4 | 1 | 15 | |
| TCGA | GOSR2 | 9570 | 26 | 6 | 64 |
Total number of gains: 100; Total number of losses: 23; Total Number of normals: 365.
Somatic mutations of GOSR2:
Generating mutation plots.
Highly correlated genes for GOSR2:
Showing top 20/504 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GOSR2 | SFR1 | 0.780683 | 3 | 0 | 3 |
| GOSR2 | GORASP2 | 0.773554 | 3 | 0 | 3 |
| GOSR2 | PIGS | 0.750516 | 3 | 0 | 3 |
| GOSR2 | TP53I11 | 0.749487 | 3 | 0 | 3 |
| GOSR2 | TMTC4 | 0.744883 | 3 | 0 | 3 |
| GOSR2 | ZNF451 | 0.739506 | 4 | 0 | 4 |
| GOSR2 | RRAS2 | 0.732936 | 4 | 0 | 4 |
| GOSR2 | GPAA1 | 0.730361 | 3 | 0 | 3 |
| GOSR2 | PPP1R37 | 0.730101 | 3 | 0 | 3 |
| GOSR2 | ANKRD10 | 0.726689 | 3 | 0 | 3 |
| GOSR2 | FANCL | 0.725891 | 4 | 0 | 3 |
| GOSR2 | PSMB10 | 0.718202 | 3 | 0 | 3 |
| GOSR2 | CMTM4 | 0.71801 | 3 | 0 | 3 |
| GOSR2 | ALS2 | 0.713822 | 4 | 0 | 3 |
| GOSR2 | ZBED1 | 0.712884 | 3 | 0 | 3 |
| GOSR2 | WDR81 | 0.711767 | 4 | 0 | 3 |
| GOSR2 | CCL5 | 0.70979 | 3 | 0 | 3 |
| GOSR2 | RAD18 | 0.709542 | 3 | 0 | 3 |
| GOSR2 | GTF2H1 | 0.708778 | 3 | 0 | 3 |
| GOSR2 | ANXA6 | 0.702794 | 3 | 0 | 3 |
For details and further investigation, click here
