PSMB10

 

Full name: proteasome subunit beta 10 Alias Symbol: LMP10|MGC1665|beta2i
Type: protein-coding gene Cytoband: 16q22.1
Entrez ID: 5699 HGNC ID: HGNC:9538 Ensembl Gene: ENSG00000205220 OMIM ID: 176847
Drug and gene relationship at DGIdb

 

Expression of PSMB10:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PSMB10 5699 202659_at 0.8052 0.1149
GSE20347 PSMB10 5699 202659_at 0.3903 0.1223
GSE23400 PSMB10 5699 202659_at 0.4076 0.0015
GSE26886 PSMB10 5699 202659_at 0.9591 0.0056
GSE29001 PSMB10 5699 202659_at 0.5752 0.0930
GSE38129 PSMB10 5699 202659_at 0.2893 0.1663
GSE45670 PSMB10 5699 202659_at 0.5598 0.0666
GSE53622 PSMB10 5699 25394 0.5779 0.0000
GSE53624 PSMB10 5699 25394 0.7607 0.0000
GSE63941 PSMB10 5699 202659_at -0.5530 0.5631
GSE77861 PSMB10 5699 202659_at 0.1017 0.6264
GSE97050 PSMB10 5699 A_33_P3288359 0.4341 0.1817
SRP007169 PSMB10 5699 RNAseq 0.5492 0.3134
SRP008496 PSMB10 5699 RNAseq 0.5824 0.1918
SRP064894 PSMB10 5699 RNAseq 1.1805 0.0027
SRP133303 PSMB10 5699 RNAseq 0.6217 0.0099
SRP159526 PSMB10 5699 RNAseq 0.2837 0.5568
SRP193095 PSMB10 5699 RNAseq 0.1069 0.6627
SRP219564 PSMB10 5699 RNAseq 1.1159 0.0140
TCGA PSMB10 5699 RNAseq 0.1988 0.0476

Upregulated datasets: 2; Downregulated datasets: 0.  

 

Survival by PSMB10 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of PSMB10:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PSMB10 5699 9 2 19
GSE20123 PSMB10 5699 9 2 19
GSE43470 PSMB10 5699 1 9 33
GSE46452 PSMB10 5699 38 1 20
GSE47630 PSMB10 5699 11 8 21
GSE54993 PSMB10 5699 2 4 64
GSE54994 PSMB10 5699 8 10 35
GSE60625 PSMB10 5699 4 0 7
GSE74703 PSMB10 5699 1 6 29
GSE74704 PSMB10 5699 5 1 14
TCGA PSMB10 5699 30 12 54

Total number of gains: 118; Total number of losses: 55; Total Number of normals: 315.  

 

Somatic mutations of PSMB10:

 

Generating mutation plots.

 

Highly correlated genes for PSMB10:

 

Showing top 20/813 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PSMB10PREX10.823784303
PSMB10SSBP40.769328303
PSMB10DHRSX0.750085303
PSMB10SLC39A30.725598303
PSMB10GOSR20.718202303
PSMB10PSMB80.71796113011
PSMB10PARP140.713824806
PSMB10TUFM0.713338303
PSMB10WDR810.712688403
PSMB10NLRC50.711893505
PSMB10TIFAB0.710929303
PSMB10HAVCR20.710279505
PSMB10ERGIC30.708871303
PSMB10HLA-F0.70670711010
PSMB10CMPK20.694936707
PSMB10SNX200.694747403
PSMB10LRRK10.693262303
PSMB10USP410.692587303
PSMB10PSMB90.69007412010
PSMB10IFI350.68930812010

For details and further investigation, click here