| Full name: keratin associated protein 5-11 | Alias Symbol: KRTAP5.11|KRTAP5-6 | ||
| Type: protein-coding gene | Cytoband: 11q13.4 | ||
| Entrez ID: 440051 | HGNC ID: HGNC:23606 | Ensembl Gene: ENSG00000204571 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of KRTAP5-11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | KRTAP5-11 | 440051 | 47658 | -0.2855 | 0.0054 | |
| GSE53624 | KRTAP5-11 | 440051 | 47658 | -1.0259 | 0.0000 | |
| GSE97050 | KRTAP5-11 | 440051 | A_33_P3372742 | -0.0756 | 0.7350 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by KRTAP5-11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KRTAP5-11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRTAP5-11 | 440051 | 11 | 6 | 13 | |
| GSE20123 | KRTAP5-11 | 440051 | 11 | 6 | 13 | |
| GSE43470 | KRTAP5-11 | 440051 | 7 | 4 | 32 | |
| GSE46452 | KRTAP5-11 | 440051 | 18 | 12 | 29 | |
| GSE47630 | KRTAP5-11 | 440051 | 11 | 9 | 20 | |
| GSE54993 | KRTAP5-11 | 440051 | 6 | 6 | 58 | |
| GSE54994 | KRTAP5-11 | 440051 | 14 | 12 | 27 | |
| GSE60625 | KRTAP5-11 | 440051 | 0 | 7 | 4 | |
| GSE74703 | KRTAP5-11 | 440051 | 6 | 3 | 27 | |
| GSE74704 | KRTAP5-11 | 440051 | 7 | 4 | 9 |
Total number of gains: 91; Total number of losses: 69; Total Number of normals: 232.
Somatic mutations of KRTAP5-11:
Generating mutation plots.
Highly correlated genes for KRTAP5-11:
Showing top 20/69 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRTAP5-11 | KRTAP5-4 | 0.857766 | 3 | 0 | 3 |
| KRTAP5-11 | GPR62 | 0.813936 | 3 | 0 | 3 |
| KRTAP5-11 | KRTAP10-8 | 0.784391 | 3 | 0 | 3 |
| KRTAP5-11 | GPHB5 | 0.766973 | 3 | 0 | 3 |
| KRTAP5-11 | KRTAP5-5 | 0.758901 | 3 | 0 | 3 |
| KRTAP5-11 | IL37 | 0.752426 | 3 | 0 | 3 |
| KRTAP5-11 | COL20A1 | 0.748541 | 3 | 0 | 3 |
| KRTAP5-11 | CLEC18C | 0.740504 | 3 | 0 | 3 |
| KRTAP5-11 | ATP2B3 | 0.720152 | 3 | 0 | 3 |
| KRTAP5-11 | DNAJB8 | 0.718781 | 3 | 0 | 3 |
| KRTAP5-11 | KRTAP5-6 | 0.714541 | 3 | 0 | 3 |
| KRTAP5-11 | BARHL2 | 0.712647 | 3 | 0 | 3 |
| KRTAP5-11 | BTBD9 | 0.698342 | 4 | 0 | 4 |
| KRTAP5-11 | FXYD2 | 0.684385 | 3 | 0 | 3 |
| KRTAP5-11 | FTCD | 0.683933 | 3 | 0 | 3 |
| KRTAP5-11 | SCNN1D | 0.664352 | 3 | 0 | 3 |
| KRTAP5-11 | MGAT5B | 0.658789 | 3 | 0 | 3 |
| KRTAP5-11 | RNF222 | 0.658649 | 3 | 0 | 3 |
| KRTAP5-11 | FSCN2 | 0.65709 | 3 | 0 | 3 |
| KRTAP5-11 | NHLRC4 | 0.657036 | 3 | 0 | 3 |
For details and further investigation, click here
