GPR19

 

Full name: G protein-coupled receptor 19 Alias Symbol: 
Type: protein-coding gene Cytoband: 12p13.1
Entrez ID: 2842 HGNC ID: HGNC:4473 Ensembl Gene: ENSG00000183150 OMIM ID: 602927
Drug and gene relationship at DGIdb

 

Expression of GPR19:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 GPR19 2842 207183_at 0.7861 0.1194
GSE20347 GPR19 2842 207183_at 0.5852 0.0075
GSE23400 GPR19 2842 207183_at 0.0014 0.9794
GSE26886 GPR19 2842 207183_at 0.8006 0.0214
GSE29001 GPR19 2842 207183_at 1.1911 0.0048
GSE38129 GPR19 2842 207183_at 0.6788 0.0004
GSE45670 GPR19 2842 207183_at 0.8959 0.0158
GSE53622 GPR19 2842 130770 2.1918 0.0000
GSE53624 GPR19 2842 130770 2.6159 0.0000
GSE63941 GPR19 2842 207183_at 2.1879 0.0062
GSE77861 GPR19 2842 207183_at 0.2306 0.2400
GSE97050 GPR19 2842 A_33_P3236813 0.3147 0.2839
SRP007169 GPR19 2842 RNAseq 3.5959 0.0030
SRP133303 GPR19 2842 RNAseq 2.5589 0.0000
SRP159526 GPR19 2842 RNAseq 3.9100 0.0000
TCGA GPR19 2842 RNAseq 1.5158 0.0000

Upregulated datasets: 8; Downregulated datasets: 0.  


 

Survival by GPR19 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of GPR19:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 GPR19 2842 6 2 22
GSE20123 GPR19 2842 6 2 22
GSE43470 GPR19 2842 10 4 29
GSE46452 GPR19 2842 10 1 48
GSE47630 GPR19 2842 13 2 25
GSE54993 GPR19 2842 2 9 59
GSE54994 GPR19 2842 10 2 41
GSE60625 GPR19 2842 0 1 10
GSE74703 GPR19 2842 9 3 24
GSE74704 GPR19 2842 4 1 15
TCGA GPR19 2842 39 7 50

Total number of gains: 109; Total number of losses: 34; Total Number of normals: 345.  


 

Somatic mutations of GPR19:

 

Generating mutation plots.

 

Highly correlated genes for GPR19:

 

Showing top 20/1415 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
GPR19TRMT2B0.759326303
GPR19MMS22L0.745777303
GPR19DKC10.74049303
GPR19PYCR20.739439303
GPR19KIF16B0.738497303
GPR19SNAP470.736388303
GPR19ALG10B0.728565303
GPR19ZNF7070.72774303
GPR19NCOR10.722405303
GPR19PTCD10.717321303
GPR19HELB0.716744303
GPR19ANAPC10.715716303
GPR19MAD2L20.71546605
GPR19UCK20.715207303
GPR19NFKBID0.713087404
GPR19SCNM10.710655303
GPR19UBE2T0.707482808
GPR19C12orf600.707083707
GPR19NF10.706661303
GPR19XXYLT10.70625404

For details and further investigation, click here