| Full name: pentatricopeptide repeat domain 1 | Alias Symbol: KIAA0632 | ||
| Type: protein-coding gene | Cytoband: 7q22.1 | ||
| Entrez ID: 26024 | HGNC ID: HGNC:22198 | Ensembl Gene: ENSG00000106246 | OMIM ID: 614774 |
| Drug and gene relationship at DGIdb | |||
Expression of PTCD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | PTCD1 | 26024 | 78582 | 0.6695 | 0.0000 | |
| GSE53624 | PTCD1 | 26024 | 78582 | 0.7410 | 0.0000 | |
| GSE97050 | PTCD1 | 26024 | A_23_P134650 | 0.4754 | 0.1545 | |
| SRP064894 | PTCD1 | 26024 | RNAseq | 0.5745 | 0.0005 | |
| SRP133303 | PTCD1 | 26024 | RNAseq | 0.4947 | 0.0003 | |
| SRP159526 | PTCD1 | 26024 | RNAseq | 0.2857 | 0.2220 | |
| SRP193095 | PTCD1 | 26024 | RNAseq | 0.7617 | 0.0000 | |
| SRP219564 | PTCD1 | 26024 | RNAseq | 0.4710 | 0.2158 | |
| TCGA | PTCD1 | 26024 | RNAseq | 0.2144 | 0.0022 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PTCD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PTCD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PTCD1 | 26024 | 13 | 0 | 17 | |
| GSE20123 | PTCD1 | 26024 | 13 | 0 | 17 | |
| GSE43470 | PTCD1 | 26024 | 6 | 1 | 36 | |
| GSE46452 | PTCD1 | 26024 | 11 | 1 | 47 | |
| GSE47630 | PTCD1 | 26024 | 8 | 3 | 29 | |
| GSE54993 | PTCD1 | 26024 | 1 | 9 | 60 | |
| GSE54994 | PTCD1 | 26024 | 16 | 3 | 34 | |
| GSE60625 | PTCD1 | 26024 | 0 | 0 | 11 | |
| GSE74703 | PTCD1 | 26024 | 6 | 1 | 29 | |
| GSE74704 | PTCD1 | 26024 | 9 | 0 | 11 | |
| TCGA | PTCD1 | 26024 | 54 | 4 | 38 |
Total number of gains: 137; Total number of losses: 22; Total Number of normals: 329.
Somatic mutations of PTCD1:
Generating mutation plots.
Highly correlated genes for PTCD1:
Showing top 20/449 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PTCD1 | DNAJC2 | 0.83022 | 3 | 0 | 3 |
| PTCD1 | ARMC10 | 0.813735 | 3 | 0 | 3 |
| PTCD1 | BUD31 | 0.809058 | 3 | 0 | 3 |
| PTCD1 | TAF6 | 0.80767 | 3 | 0 | 3 |
| PTCD1 | FAM200A | 0.805418 | 3 | 0 | 3 |
| PTCD1 | PDAP1 | 0.792155 | 3 | 0 | 3 |
| PTCD1 | SAMD1 | 0.790646 | 3 | 0 | 3 |
| PTCD1 | SRRT | 0.783262 | 3 | 0 | 3 |
| PTCD1 | ZNHIT1 | 0.780977 | 3 | 0 | 3 |
| PTCD1 | XPO1 | 0.776541 | 3 | 0 | 3 |
| PTCD1 | BCL7A | 0.772041 | 3 | 0 | 3 |
| PTCD1 | ORC5 | 0.767385 | 3 | 0 | 3 |
| PTCD1 | BRCA1 | 0.767119 | 3 | 0 | 3 |
| PTCD1 | POLR2J | 0.765748 | 3 | 0 | 3 |
| PTCD1 | PSMC2 | 0.7652 | 3 | 0 | 3 |
| PTCD1 | NCAPD2 | 0.764595 | 3 | 0 | 3 |
| PTCD1 | CSE1L | 0.762797 | 3 | 0 | 3 |
| PTCD1 | CDCA3 | 0.758857 | 3 | 0 | 3 |
| PTCD1 | MRPL47 | 0.758729 | 3 | 0 | 3 |
| PTCD1 | C12orf65 | 0.756232 | 3 | 0 | 3 |
For details and further investigation, click here
