| Full name: ALG10 alpha-1,2-glucosyltransferase B | Alias Symbol: KCR1 | ||
| Type: protein-coding gene | Cytoband: 12q12 | ||
| Entrez ID: 144245 | HGNC ID: HGNC:31088 | Ensembl Gene: ENSG00000175548 | OMIM ID: 603313 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of ALG10B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | ALG10B | 144245 | 101332 | 0.5699 | 0.0000 | |
| GSE53624 | ALG10B | 144245 | 101332 | 0.5994 | 0.0000 | |
| GSE97050 | ALG10B | 144245 | A_32_P89679 | 0.1735 | 0.4966 | |
| SRP007169 | ALG10B | 144245 | RNAseq | 1.3849 | 0.0131 | |
| SRP008496 | ALG10B | 144245 | RNAseq | 1.2468 | 0.0001 | |
| SRP064894 | ALG10B | 144245 | RNAseq | 0.3515 | 0.1138 | |
| SRP133303 | ALG10B | 144245 | RNAseq | 0.6782 | 0.0023 | |
| SRP159526 | ALG10B | 144245 | RNAseq | 0.4303 | 0.2000 | |
| SRP193095 | ALG10B | 144245 | RNAseq | 0.2505 | 0.0085 | |
| SRP219564 | ALG10B | 144245 | RNAseq | 0.0580 | 0.8012 | |
| TCGA | ALG10B | 144245 | RNAseq | -0.0368 | 0.7180 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by ALG10B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ALG10B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ALG10B | 144245 | 7 | 1 | 22 | |
| GSE20123 | ALG10B | 144245 | 7 | 1 | 22 | |
| GSE43470 | ALG10B | 144245 | 5 | 3 | 35 | |
| GSE46452 | ALG10B | 144245 | 8 | 1 | 50 | |
| GSE47630 | ALG10B | 144245 | 11 | 2 | 27 | |
| GSE54993 | ALG10B | 144245 | 1 | 8 | 61 | |
| GSE54994 | ALG10B | 144245 | 6 | 1 | 46 | |
| GSE60625 | ALG10B | 144245 | 0 | 0 | 11 | |
| GSE74703 | ALG10B | 144245 | 5 | 2 | 29 | |
| GSE74704 | ALG10B | 144245 | 4 | 1 | 15 | |
| TCGA | ALG10B | 144245 | 39 | 5 | 52 |
Total number of gains: 93; Total number of losses: 25; Total Number of normals: 370.
Somatic mutations of ALG10B:
Generating mutation plots.
Highly correlated genes for ALG10B:
Showing top 20/239 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ALG10B | CENPL | 0.765553 | 3 | 0 | 3 |
| ALG10B | KIF3B | 0.748474 | 3 | 0 | 3 |
| ALG10B | FAM200A | 0.742873 | 3 | 0 | 3 |
| ALG10B | USP1 | 0.740688 | 3 | 0 | 3 |
| ALG10B | C12orf60 | 0.740127 | 3 | 0 | 3 |
| ALG10B | CEP41 | 0.731404 | 3 | 0 | 3 |
| ALG10B | GPR19 | 0.728565 | 3 | 0 | 3 |
| ALG10B | GMCL1 | 0.723355 | 3 | 0 | 3 |
| ALG10B | PHB2 | 0.715578 | 3 | 0 | 3 |
| ALG10B | LRRC23 | 0.71266 | 3 | 0 | 3 |
| ALG10B | TGIF2 | 0.706824 | 3 | 0 | 3 |
| ALG10B | POLR3F | 0.70517 | 3 | 0 | 3 |
| ALG10B | NCAPD2 | 0.704246 | 3 | 0 | 3 |
| ALG10B | USP39 | 0.703585 | 3 | 0 | 3 |
| ALG10B | CENPH | 0.702869 | 3 | 0 | 3 |
| ALG10B | GTPBP10 | 0.701181 | 3 | 0 | 3 |
| ALG10B | LRRCC1 | 0.699991 | 3 | 0 | 3 |
| ALG10B | CASP8AP2 | 0.698332 | 3 | 0 | 3 |
| ALG10B | GPN3 | 0.696191 | 3 | 0 | 3 |
| ALG10B | WDR54 | 0.695648 | 3 | 0 | 3 |
For details and further investigation, click here
