| Full name: uridine-cytidine kinase 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q24.1 | ||
| Entrez ID: 7371 | HGNC ID: HGNC:12562 | Ensembl Gene: ENSG00000143179 | OMIM ID: 609329 |
| Drug and gene relationship at DGIdb | |||
Expression of UCK2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | UCK2 | 7371 | 3021 | 0.8258 | 0.0000 | |
| GSE53624 | UCK2 | 7371 | 3021 | 1.1806 | 0.0000 | |
| GSE97050 | UCK2 | 7371 | A_23_P487 | 0.8484 | 0.1506 | |
| SRP007169 | UCK2 | 7371 | RNAseq | -0.3912 | 0.3613 | |
| SRP008496 | UCK2 | 7371 | RNAseq | -0.0123 | 0.9611 | |
| SRP064894 | UCK2 | 7371 | RNAseq | 0.6634 | 0.0006 | |
| SRP133303 | UCK2 | 7371 | RNAseq | 0.1710 | 0.2504 | |
| SRP159526 | UCK2 | 7371 | RNAseq | 0.6287 | 0.0556 | |
| SRP193095 | UCK2 | 7371 | RNAseq | 0.2281 | 0.0304 | |
| SRP219564 | UCK2 | 7371 | RNAseq | 0.8143 | 0.0885 | |
| TCGA | UCK2 | 7371 | RNAseq | 0.4196 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by UCK2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UCK2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UCK2 | 7371 | 10 | 2 | 18 | |
| GSE20123 | UCK2 | 7371 | 10 | 2 | 18 | |
| GSE43470 | UCK2 | 7371 | 7 | 2 | 34 | |
| GSE46452 | UCK2 | 7371 | 2 | 1 | 56 | |
| GSE47630 | UCK2 | 7371 | 14 | 0 | 26 | |
| GSE54993 | UCK2 | 7371 | 0 | 5 | 65 | |
| GSE54994 | UCK2 | 7371 | 16 | 0 | 37 | |
| GSE60625 | UCK2 | 7371 | 0 | 0 | 11 | |
| GSE74703 | UCK2 | 7371 | 7 | 2 | 27 | |
| GSE74704 | UCK2 | 7371 | 4 | 1 | 15 | |
| TCGA | UCK2 | 7371 | 44 | 3 | 49 |
Total number of gains: 114; Total number of losses: 18; Total Number of normals: 356.
Somatic mutations of UCK2:
Generating mutation plots.
Highly correlated genes for UCK2:
Showing top 20/566 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UCK2 | TTK | 0.836888 | 3 | 0 | 3 |
| UCK2 | BLM | 0.826089 | 3 | 0 | 3 |
| UCK2 | TIMELESS | 0.81811 | 3 | 0 | 3 |
| UCK2 | ASPM | 0.812562 | 3 | 0 | 3 |
| UCK2 | CCNF | 0.805302 | 3 | 0 | 3 |
| UCK2 | GINS1 | 0.800631 | 3 | 0 | 3 |
| UCK2 | KIF18A | 0.799657 | 3 | 0 | 3 |
| UCK2 | CAD | 0.79755 | 3 | 0 | 3 |
| UCK2 | HJURP | 0.796634 | 3 | 0 | 3 |
| UCK2 | CLSPN | 0.793942 | 3 | 0 | 3 |
| UCK2 | KIFC1 | 0.793392 | 3 | 0 | 3 |
| UCK2 | RFWD3 | 0.789885 | 3 | 0 | 3 |
| UCK2 | FLVCR1 | 0.788763 | 3 | 0 | 3 |
| UCK2 | NOP2 | 0.787559 | 3 | 0 | 3 |
| UCK2 | DDX39A | 0.786666 | 3 | 0 | 3 |
| UCK2 | ITPR3 | 0.786243 | 3 | 0 | 3 |
| UCK2 | POLR1B | 0.785186 | 3 | 0 | 3 |
| UCK2 | DCAF13 | 0.784645 | 3 | 0 | 3 |
| UCK2 | SLC25A17 | 0.784314 | 3 | 0 | 3 |
| UCK2 | FJX1 | 0.783266 | 3 | 0 | 3 |
For details and further investigation, click here
