| Full name: chromosome 12 open reading frame 60 | Alias Symbol: MGC47869 | ||
| Type: protein-coding gene | Cytoband: 12p12.3 | ||
| Entrez ID: 144608 | HGNC ID: HGNC:28726 | Ensembl Gene: ENSG00000182993 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C12orf60:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C12orf60 | 144608 | 229888_at | 0.2527 | 0.6176 | |
| GSE26886 | C12orf60 | 144608 | 229888_at | 0.3624 | 0.1072 | |
| GSE45670 | C12orf60 | 144608 | 229888_at | 0.6563 | 0.0012 | |
| GSE53622 | C12orf60 | 144608 | 21995 | 0.7286 | 0.0000 | |
| GSE53624 | C12orf60 | 144608 | 21995 | 1.1125 | 0.0000 | |
| GSE63941 | C12orf60 | 144608 | 229888_at | 1.4901 | 0.0162 | |
| GSE77861 | C12orf60 | 144608 | 229888_at | 0.0286 | 0.8741 | |
| GSE97050 | C12orf60 | 144608 | A_23_P364544 | 0.0538 | 0.8820 | |
| SRP133303 | C12orf60 | 144608 | RNAseq | 0.7363 | 0.0199 | |
| SRP159526 | C12orf60 | 144608 | RNAseq | 0.7369 | 0.2758 | |
| TCGA | C12orf60 | 144608 | RNAseq | 0.0751 | 0.6847 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by C12orf60 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C12orf60:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C12orf60 | 144608 | 6 | 2 | 22 | |
| GSE20123 | C12orf60 | 144608 | 6 | 2 | 22 | |
| GSE43470 | C12orf60 | 144608 | 9 | 4 | 30 | |
| GSE46452 | C12orf60 | 144608 | 10 | 1 | 48 | |
| GSE47630 | C12orf60 | 144608 | 14 | 1 | 25 | |
| GSE54993 | C12orf60 | 144608 | 1 | 9 | 60 | |
| GSE54994 | C12orf60 | 144608 | 10 | 2 | 41 | |
| GSE60625 | C12orf60 | 144608 | 0 | 1 | 10 | |
| GSE74703 | C12orf60 | 144608 | 9 | 3 | 24 | |
| GSE74704 | C12orf60 | 144608 | 4 | 1 | 15 | |
| TCGA | C12orf60 | 144608 | 41 | 5 | 50 |
Total number of gains: 110; Total number of losses: 31; Total Number of normals: 347.
Somatic mutations of C12orf60:
Generating mutation plots.
Highly correlated genes for C12orf60:
Showing top 20/1029 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C12orf60 | M6PR | 0.763351 | 4 | 0 | 4 |
| C12orf60 | ALG10B | 0.740127 | 3 | 0 | 3 |
| C12orf60 | FAM192A | 0.739404 | 3 | 0 | 3 |
| C12orf60 | TMPO | 0.736089 | 3 | 0 | 3 |
| C12orf60 | NIPA2 | 0.734826 | 3 | 0 | 3 |
| C12orf60 | EMG1 | 0.731439 | 5 | 0 | 4 |
| C12orf60 | SAMM50 | 0.721049 | 3 | 0 | 3 |
| C12orf60 | HSD17B1 | 0.717367 | 4 | 0 | 4 |
| C12orf60 | GYG2 | 0.714834 | 3 | 0 | 3 |
| C12orf60 | FN3KRP | 0.70901 | 3 | 0 | 3 |
| C12orf60 | GPR19 | 0.707083 | 7 | 0 | 7 |
| C12orf60 | EIF4G1 | 0.706424 | 3 | 0 | 3 |
| C12orf60 | OIP5 | 0.706235 | 3 | 0 | 3 |
| C12orf60 | ZNF384 | 0.704663 | 5 | 0 | 5 |
| C12orf60 | EARS2 | 0.702572 | 5 | 0 | 5 |
| C12orf60 | RHBDD2 | 0.700491 | 6 | 0 | 5 |
| C12orf60 | RNASEH1 | 0.69821 | 4 | 0 | 4 |
| C12orf60 | CELSR2 | 0.697033 | 3 | 0 | 3 |
| C12orf60 | WBP11 | 0.694397 | 7 | 0 | 7 |
| C12orf60 | DCTPP1 | 0.69362 | 5 | 0 | 5 |
For details and further investigation, click here
