| Full name: G protein-coupled receptor class C group 5 member C | Alias Symbol: RAIG-3 | ||
| Type: protein-coding gene | Cytoband: 17q25.1 | ||
| Entrez ID: 55890 | HGNC ID: HGNC:13309 | Ensembl Gene: ENSG00000170412 | OMIM ID: 605949 |
| Drug and gene relationship at DGIdb | |||
Expression of GPRC5C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GPRC5C | 55890 | 219327_s_at | 0.2370 | 0.7075 | |
| GSE20347 | GPRC5C | 55890 | 219327_s_at | 0.1585 | 0.4087 | |
| GSE23400 | GPRC5C | 55890 | 219327_s_at | 0.0074 | 0.8676 | |
| GSE26886 | GPRC5C | 55890 | 219327_s_at | 1.2864 | 0.0000 | |
| GSE29001 | GPRC5C | 55890 | 219327_s_at | 0.1356 | 0.6704 | |
| GSE38129 | GPRC5C | 55890 | 219327_s_at | 0.0525 | 0.8475 | |
| GSE45670 | GPRC5C | 55890 | 219327_s_at | 0.0412 | 0.8539 | |
| GSE53622 | GPRC5C | 55890 | 42374 | 0.6156 | 0.0000 | |
| GSE53624 | GPRC5C | 55890 | 42374 | 0.4936 | 0.0000 | |
| GSE63941 | GPRC5C | 55890 | 219327_s_at | 0.5803 | 0.5955 | |
| GSE77861 | GPRC5C | 55890 | 219327_s_at | 0.4049 | 0.0449 | |
| GSE97050 | GPRC5C | 55890 | A_23_P38167 | 0.1493 | 0.7495 | |
| SRP064894 | GPRC5C | 55890 | RNAseq | 0.8064 | 0.0589 | |
| SRP133303 | GPRC5C | 55890 | RNAseq | 0.4175 | 0.0986 | |
| SRP159526 | GPRC5C | 55890 | RNAseq | 0.3746 | 0.4909 | |
| SRP193095 | GPRC5C | 55890 | RNAseq | -0.0674 | 0.8576 | |
| SRP219564 | GPRC5C | 55890 | RNAseq | 1.2188 | 0.0259 | |
| TCGA | GPRC5C | 55890 | RNAseq | -0.8560 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by GPRC5C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPRC5C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPRC5C | 55890 | 3 | 2 | 25 | |
| GSE20123 | GPRC5C | 55890 | 3 | 2 | 25 | |
| GSE43470 | GPRC5C | 55890 | 5 | 3 | 35 | |
| GSE46452 | GPRC5C | 55890 | 33 | 0 | 26 | |
| GSE47630 | GPRC5C | 55890 | 8 | 1 | 31 | |
| GSE54993 | GPRC5C | 55890 | 2 | 5 | 63 | |
| GSE54994 | GPRC5C | 55890 | 10 | 4 | 39 | |
| GSE60625 | GPRC5C | 55890 | 6 | 0 | 5 | |
| GSE74703 | GPRC5C | 55890 | 5 | 1 | 30 | |
| GSE74704 | GPRC5C | 55890 | 3 | 1 | 16 | |
| TCGA | GPRC5C | 55890 | 32 | 10 | 54 |
Total number of gains: 110; Total number of losses: 29; Total Number of normals: 349.
Somatic mutations of GPRC5C:
Generating mutation plots.
Highly correlated genes for GPRC5C:
Showing top 20/270 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPRC5C | COPRS | 0.774864 | 3 | 0 | 3 |
| GPRC5C | ENAH | 0.732212 | 4 | 0 | 4 |
| GPRC5C | PPP2R5B | 0.723427 | 3 | 0 | 3 |
| GPRC5C | SNX10 | 0.712258 | 3 | 0 | 3 |
| GPRC5C | POP7 | 0.710722 | 3 | 0 | 3 |
| GPRC5C | ANKRD52 | 0.704466 | 3 | 0 | 3 |
| GPRC5C | LAMTOR4 | 0.69784 | 3 | 0 | 3 |
| GPRC5C | TRIM45 | 0.686337 | 3 | 0 | 3 |
| GPRC5C | ZNF26 | 0.685918 | 4 | 0 | 4 |
| GPRC5C | ARNT2 | 0.684755 | 4 | 0 | 4 |
| GPRC5C | KXD1 | 0.682854 | 4 | 0 | 3 |
| GPRC5C | RPS6KA1 | 0.676797 | 3 | 0 | 3 |
| GPRC5C | YDJC | 0.675377 | 4 | 0 | 3 |
| GPRC5C | TNIP2 | 0.667427 | 3 | 0 | 3 |
| GPRC5C | XPR1 | 0.666681 | 3 | 0 | 3 |
| GPRC5C | SEMA3C | 0.663281 | 4 | 0 | 3 |
| GPRC5C | HOXC9 | 0.661091 | 3 | 0 | 3 |
| GPRC5C | SLC27A5 | 0.658892 | 3 | 0 | 3 |
| GPRC5C | GPX4 | 0.657987 | 5 | 0 | 4 |
| GPRC5C | MAF1 | 0.656677 | 3 | 0 | 3 |
For details and further investigation, click here
