| Full name: TNFAIP3 interacting protein 2 | Alias Symbol: ABIN-2|MGC4289|KLIP|FLIP1 | ||
| Type: protein-coding gene | Cytoband: 4p16.3 | ||
| Entrez ID: 79155 | HGNC ID: HGNC:19118 | Ensembl Gene: ENSG00000168884 | OMIM ID: 610669 |
| Drug and gene relationship at DGIdb | |||
Expression of TNIP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TNIP2 | 79155 | 48531_at | 0.7282 | 0.0265 | |
| GSE20347 | TNIP2 | 79155 | 48531_at | 0.2583 | 0.0879 | |
| GSE23400 | TNIP2 | 79155 | 218335_x_at | 0.2398 | 0.0000 | |
| GSE26886 | TNIP2 | 79155 | 48531_at | 0.7993 | 0.0005 | |
| GSE29001 | TNIP2 | 79155 | 218335_x_at | 0.2504 | 0.0529 | |
| GSE38129 | TNIP2 | 79155 | 48531_at | 0.2942 | 0.0073 | |
| GSE45670 | TNIP2 | 79155 | 48531_at | 0.5923 | 0.0003 | |
| GSE53622 | TNIP2 | 79155 | 52296 | 0.3979 | 0.0000 | |
| GSE53624 | TNIP2 | 79155 | 52296 | 0.4026 | 0.0000 | |
| GSE63941 | TNIP2 | 79155 | 48531_at | -0.7464 | 0.0274 | |
| GSE77861 | TNIP2 | 79155 | 218335_x_at | 0.4589 | 0.1435 | |
| GSE97050 | TNIP2 | 79155 | A_23_P258418 | 0.4718 | 0.1711 | |
| SRP007169 | TNIP2 | 79155 | RNAseq | 0.2897 | 0.5516 | |
| SRP008496 | TNIP2 | 79155 | RNAseq | 0.3136 | 0.3316 | |
| SRP064894 | TNIP2 | 79155 | RNAseq | 0.6946 | 0.0021 | |
| SRP133303 | TNIP2 | 79155 | RNAseq | 0.4092 | 0.0071 | |
| SRP159526 | TNIP2 | 79155 | RNAseq | -0.0104 | 0.9660 | |
| SRP193095 | TNIP2 | 79155 | RNAseq | 0.2729 | 0.0221 | |
| SRP219564 | TNIP2 | 79155 | RNAseq | 0.1144 | 0.7065 | |
| TCGA | TNIP2 | 79155 | RNAseq | 0.0118 | 0.8249 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TNIP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TNIP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TNIP2 | 79155 | 0 | 16 | 14 | |
| GSE20123 | TNIP2 | 79155 | 0 | 16 | 14 | |
| GSE43470 | TNIP2 | 79155 | 0 | 17 | 26 | |
| GSE46452 | TNIP2 | 79155 | 1 | 36 | 22 | |
| GSE47630 | TNIP2 | 79155 | 1 | 19 | 20 | |
| GSE54993 | TNIP2 | 79155 | 11 | 0 | 59 | |
| GSE54994 | TNIP2 | 79155 | 3 | 12 | 38 | |
| GSE60625 | TNIP2 | 79155 | 0 | 0 | 11 | |
| GSE74703 | TNIP2 | 79155 | 0 | 13 | 23 | |
| GSE74704 | TNIP2 | 79155 | 0 | 8 | 12 | |
| TCGA | TNIP2 | 79155 | 7 | 48 | 41 |
Total number of gains: 23; Total number of losses: 185; Total Number of normals: 280.
Somatic mutations of TNIP2:
Generating mutation plots.
Highly correlated genes for TNIP2:
Showing top 20/398 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TNIP2 | LRFN3 | 0.734551 | 3 | 0 | 3 |
| TNIP2 | GPRIN1 | 0.73149 | 4 | 0 | 4 |
| TNIP2 | COL27A1 | 0.716511 | 5 | 0 | 5 |
| TNIP2 | DNLZ | 0.714865 | 3 | 0 | 3 |
| TNIP2 | GNPNAT1 | 0.714486 | 3 | 0 | 3 |
| TNIP2 | SIGIRR | 0.713355 | 3 | 0 | 3 |
| TNIP2 | EML6 | 0.712744 | 3 | 0 | 3 |
| TNIP2 | BEND3 | 0.699524 | 6 | 0 | 5 |
| TNIP2 | GFI1 | 0.689313 | 3 | 0 | 3 |
| TNIP2 | NPW | 0.686902 | 4 | 0 | 4 |
| TNIP2 | C4orf46 | 0.670784 | 4 | 0 | 4 |
| TNIP2 | CDC42EP2 | 0.670212 | 4 | 0 | 3 |
| TNIP2 | GPRC5C | 0.667427 | 3 | 0 | 3 |
| TNIP2 | TIGD5 | 0.665018 | 5 | 0 | 3 |
| TNIP2 | WDR83 | 0.664301 | 3 | 0 | 3 |
| TNIP2 | ZNF593 | 0.663451 | 7 | 0 | 6 |
| TNIP2 | ATG4D | 0.66041 | 3 | 0 | 3 |
| TNIP2 | SHC3 | 0.653075 | 3 | 0 | 3 |
| TNIP2 | NUDT22 | 0.648991 | 4 | 0 | 3 |
| TNIP2 | AMPD2 | 0.648846 | 11 | 0 | 8 |
For details and further investigation, click here
