SNX10

 

Full name: sorting nexin 10 Alias Symbol: 
Type: protein-coding gene Cytoband: 7p15.2
Entrez ID: 29887 HGNC ID: HGNC:14974 Ensembl Gene: ENSG00000086300 OMIM ID: 614780
Drug and gene relationship at DGIdb

 

Expression of SNX10:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SNX10 29887 218404_at 1.8468 0.0502
GSE20347 SNX10 29887 218404_at 2.2101 0.0000
GSE23400 SNX10 29887 218404_at 0.8948 0.0000
GSE26886 SNX10 29887 218404_at 2.8231 0.0000
GSE29001 SNX10 29887 218404_at 2.4617 0.0001
GSE38129 SNX10 29887 218404_at 2.3095 0.0000
GSE45670 SNX10 29887 218404_at 1.6123 0.0016
GSE53622 SNX10 29887 83742 2.0796 0.0000
GSE53624 SNX10 29887 83742 2.1292 0.0000
GSE63941 SNX10 29887 218404_at 3.2927 0.0034
GSE77861 SNX10 29887 218404_at 1.5087 0.0086
GSE97050 SNX10 29887 A_24_P98109 1.2287 0.1421
SRP007169 SNX10 29887 RNAseq 3.7142 0.0000
SRP008496 SNX10 29887 RNAseq 3.2222 0.0000
SRP064894 SNX10 29887 RNAseq 2.8274 0.0000
SRP133303 SNX10 29887 RNAseq 2.5139 0.0000
SRP159526 SNX10 29887 RNAseq 1.8602 0.0002
SRP193095 SNX10 29887 RNAseq 2.3083 0.0000
SRP219564 SNX10 29887 RNAseq 2.5529 0.0001
TCGA SNX10 29887 RNAseq 1.0640 0.0000

Upregulated datasets: 17; Downregulated datasets: 0.  


 

Survival by SNX10 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of SNX10:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SNX10 29887 16 1 13
GSE20123 SNX10 29887 16 1 13
GSE43470 SNX10 29887 4 0 39
GSE46452 SNX10 29887 10 2 47
GSE47630 SNX10 29887 9 1 30
GSE54993 SNX10 29887 0 6 64
GSE54994 SNX10 29887 21 2 30
GSE60625 SNX10 29887 0 0 11
GSE74703 SNX10 29887 4 0 32
GSE74704 SNX10 29887 10 1 9
TCGA SNX10 29887 55 6 35

Total number of gains: 145; Total number of losses: 20; Total Number of normals: 323.  


 

Somatic mutations of SNX10:

 

Generating mutation plots.

 

Highly correlated genes for SNX10:

 

Showing top 20/1840 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SNX10SPP10.79573111011
SNX10MFAP20.79036111011
SNX10CKS1B0.78577412012
SNX10TTYH30.779532807
SNX10BID0.77928111011
SNX10CBX30.77240912012
SNX10PLA2G70.7637412011
SNX10LPCAT10.7586611010
SNX10SLC25A320.7541110010
SNX10LAMC20.7539812011
SNX10PSMB20.75260811011
SNX10FNDC3B0.75199212012
SNX10MSN0.74914310010
SNX10WDR660.749128808
SNX10VOPP10.74889711010
SNX10SPRR2G0.747367303
SNX10COLGALT10.74650310010
SNX10PLAU0.74582812011
SNX10RFC40.74536212012
SNX10MET0.74379511010

For details and further investigation, click here