| Full name: casein kappa | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4q13.3 | ||
| Entrez ID: 1448 | HGNC ID: HGNC:2446 | Ensembl Gene: ENSG00000171209 | OMIM ID: 601695 |
| Drug and gene relationship at DGIdb | |||
Expression of CSN3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CSN3 | 1448 | 207803_s_at | -0.0317 | 0.9026 | |
| GSE20347 | CSN3 | 1448 | 207803_s_at | 0.5462 | 0.4077 | |
| GSE23400 | CSN3 | 1448 | 207803_s_at | -0.0923 | 0.0935 | |
| GSE26886 | CSN3 | 1448 | 207803_s_at | 0.0658 | 0.5179 | |
| GSE29001 | CSN3 | 1448 | 207803_s_at | -0.2525 | 0.1235 | |
| GSE38129 | CSN3 | 1448 | 207803_s_at | 0.2411 | 0.5563 | |
| GSE45670 | CSN3 | 1448 | 207803_s_at | -0.0494 | 0.7400 | |
| GSE53622 | CSN3 | 1448 | 4451 | -0.7779 | 0.0000 | |
| GSE53624 | CSN3 | 1448 | 4451 | -1.1732 | 0.0000 | |
| GSE63941 | CSN3 | 1448 | 207803_s_at | 0.0701 | 0.6811 | |
| GSE77861 | CSN3 | 1448 | 207803_s_at | -0.0640 | 0.6858 | |
| TCGA | CSN3 | 1448 | RNAseq | 0.6614 | 0.7063 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CSN3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CSN3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CSN3 | 1448 | 1 | 10 | 19 | |
| GSE20123 | CSN3 | 1448 | 1 | 11 | 18 | |
| GSE43470 | CSN3 | 1448 | 0 | 13 | 30 | |
| GSE46452 | CSN3 | 1448 | 2 | 35 | 22 | |
| GSE47630 | CSN3 | 1448 | 1 | 18 | 21 | |
| GSE54993 | CSN3 | 1448 | 7 | 0 | 63 | |
| GSE54994 | CSN3 | 1448 | 1 | 9 | 43 | |
| GSE60625 | CSN3 | 1448 | 0 | 0 | 11 | |
| GSE74703 | CSN3 | 1448 | 0 | 11 | 25 | |
| GSE74704 | CSN3 | 1448 | 0 | 7 | 13 | |
| TCGA | CSN3 | 1448 | 15 | 28 | 53 |
Total number of gains: 28; Total number of losses: 142; Total Number of normals: 318.
Somatic mutations of CSN3:
Generating mutation plots.
Highly correlated genes for CSN3:
Showing top 20/234 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CSN3 | EPHA7 | 0.755539 | 3 | 0 | 3 |
| CSN3 | ARNT2 | 0.749335 | 3 | 0 | 3 |
| CSN3 | MYBPC1 | 0.744281 | 4 | 0 | 3 |
| CSN3 | CSN2 | 0.744106 | 7 | 0 | 7 |
| CSN3 | TMEM8B | 0.738848 | 3 | 0 | 3 |
| CSN3 | GPSM3 | 0.73391 | 3 | 0 | 3 |
| CSN3 | PSG9 | 0.702867 | 3 | 0 | 3 |
| CSN3 | F7 | 0.700188 | 3 | 0 | 3 |
| CSN3 | GRIK3 | 0.689233 | 4 | 0 | 4 |
| CSN3 | ING4 | 0.683679 | 3 | 0 | 3 |
| CSN3 | PPP5D1 | 0.669675 | 3 | 0 | 3 |
| CSN3 | EDDM3A | 0.669215 | 4 | 0 | 3 |
| CSN3 | LINC00652 | 0.668524 | 3 | 0 | 3 |
| CSN3 | FABP7 | 0.664598 | 6 | 0 | 3 |
| CSN3 | KLC4 | 0.662534 | 3 | 0 | 3 |
| CSN3 | NPTX2 | 0.657394 | 4 | 0 | 3 |
| CSN3 | BPY2 | 0.650863 | 3 | 0 | 3 |
| CSN3 | FOXN3-AS2 | 0.647911 | 4 | 0 | 4 |
| CSN3 | MC2R | 0.646385 | 4 | 0 | 3 |
| CSN3 | LMX1B | 0.644492 | 4 | 0 | 3 |
For details and further investigation, click here
