| Full name: protein disulfide isomerase family A member 5 | Alias Symbol: PDIR|FLJ30401 | ||
| Type: protein-coding gene | Cytoband: 3q21.1 | ||
| Entrez ID: 10954 | HGNC ID: HGNC:24811 | Ensembl Gene: ENSG00000065485 | OMIM ID: 616942 |
| Drug and gene relationship at DGIdb | |||
Expression of PDIA5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | PDIA5 | 10954 | 12979 | 0.8772 | 0.0000 | |
| GSE53624 | PDIA5 | 10954 | 124828 | 1.4680 | 0.0000 | |
| GSE97050 | PDIA5 | 10954 | A_33_P3254634 | 0.6223 | 0.1636 | |
| SRP007169 | PDIA5 | 10954 | RNAseq | 4.5616 | 0.0000 | |
| SRP008496 | PDIA5 | 10954 | RNAseq | 3.2902 | 0.0000 | |
| SRP064894 | PDIA5 | 10954 | RNAseq | 1.5194 | 0.0000 | |
| SRP133303 | PDIA5 | 10954 | RNAseq | 1.4563 | 0.0000 | |
| SRP159526 | PDIA5 | 10954 | RNAseq | 1.4421 | 0.0004 | |
| SRP193095 | PDIA5 | 10954 | RNAseq | 0.9274 | 0.0043 | |
| SRP219564 | PDIA5 | 10954 | RNAseq | 1.2325 | 0.0063 | |
| TCGA | PDIA5 | 10954 | RNAseq | -0.2015 | 0.0142 |
Upregulated datasets: 7; Downregulated datasets: 0.
Survival by PDIA5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PDIA5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PDIA5 | 10954 | 17 | 0 | 13 | |
| GSE20123 | PDIA5 | 10954 | 17 | 0 | 13 | |
| GSE43470 | PDIA5 | 10954 | 20 | 0 | 23 | |
| GSE46452 | PDIA5 | 10954 | 14 | 5 | 40 | |
| GSE47630 | PDIA5 | 10954 | 17 | 4 | 19 | |
| GSE54993 | PDIA5 | 10954 | 2 | 7 | 61 | |
| GSE54994 | PDIA5 | 10954 | 30 | 4 | 19 | |
| GSE60625 | PDIA5 | 10954 | 0 | 6 | 5 | |
| GSE74703 | PDIA5 | 10954 | 16 | 0 | 20 | |
| GSE74704 | PDIA5 | 10954 | 13 | 0 | 7 | |
| TCGA | PDIA5 | 10954 | 54 | 6 | 36 |
Total number of gains: 200; Total number of losses: 32; Total Number of normals: 256.
Somatic mutations of PDIA5:
Generating mutation plots.
Highly correlated genes for PDIA5:
Showing top 20/733 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PDIA5 | MARCKSL1 | 0.820919 | 3 | 0 | 3 |
| PDIA5 | SLC17A9 | 0.802106 | 3 | 0 | 3 |
| PDIA5 | GPX8 | 0.797172 | 3 | 0 | 3 |
| PDIA5 | TREM2 | 0.796774 | 3 | 0 | 3 |
| PDIA5 | CD14 | 0.796621 | 3 | 0 | 3 |
| PDIA5 | C11orf24 | 0.796232 | 3 | 0 | 3 |
| PDIA5 | TTYH3 | 0.795145 | 3 | 0 | 3 |
| PDIA5 | COL5A1 | 0.790153 | 3 | 0 | 3 |
| PDIA5 | APOE | 0.789668 | 3 | 0 | 3 |
| PDIA5 | RCN1 | 0.786114 | 3 | 0 | 3 |
| PDIA5 | ARPC1B | 0.785301 | 3 | 0 | 3 |
| PDIA5 | LOXL2 | 0.781955 | 3 | 0 | 3 |
| PDIA5 | NOX4 | 0.777347 | 3 | 0 | 3 |
| PDIA5 | BSG | 0.77664 | 3 | 0 | 3 |
| PDIA5 | APOC1 | 0.776027 | 3 | 0 | 3 |
| PDIA5 | GALNT10 | 0.774645 | 3 | 0 | 3 |
| PDIA5 | CYBA | 0.773457 | 3 | 0 | 3 |
| PDIA5 | ACP2 | 0.772563 | 3 | 0 | 3 |
| PDIA5 | GNA12 | 0.77147 | 3 | 0 | 3 |
| PDIA5 | LPCAT1 | 0.770278 | 3 | 0 | 3 |
For details and further investigation, click here
