| Full name: solute carrier family 39 member 1 | Alias Symbol: ZIP1 | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 27173 | HGNC ID: HGNC:12876 | Ensembl Gene: ENSG00000143570 | OMIM ID: 604740 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC39A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC39A1 | 27173 | 217778_at | 0.6459 | 0.1171 | |
| GSE20347 | SLC39A1 | 27173 | 217778_at | 0.0401 | 0.7009 | |
| GSE23400 | SLC39A1 | 27173 | 217778_at | 0.2319 | 0.0000 | |
| GSE26886 | SLC39A1 | 27173 | 217778_at | 0.5695 | 0.0078 | |
| GSE29001 | SLC39A1 | 27173 | 217778_at | 0.4097 | 0.0497 | |
| GSE38129 | SLC39A1 | 27173 | 217778_at | 0.2589 | 0.1814 | |
| GSE45670 | SLC39A1 | 27173 | 217778_at | 0.4589 | 0.0003 | |
| GSE63941 | SLC39A1 | 27173 | 217778_at | 0.0223 | 0.9641 | |
| GSE77861 | SLC39A1 | 27173 | 217778_at | 0.5620 | 0.0414 | |
| GSE97050 | SLC39A1 | 27173 | A_23_P23575 | -0.0898 | 0.7262 | |
| SRP007169 | SLC39A1 | 27173 | RNAseq | 0.0731 | 0.7967 | |
| SRP008496 | SLC39A1 | 27173 | RNAseq | 0.3224 | 0.0546 | |
| SRP064894 | SLC39A1 | 27173 | RNAseq | 0.7702 | 0.0000 | |
| SRP133303 | SLC39A1 | 27173 | RNAseq | 0.7267 | 0.0000 | |
| SRP159526 | SLC39A1 | 27173 | RNAseq | 0.7518 | 0.0000 | |
| SRP193095 | SLC39A1 | 27173 | RNAseq | 0.7183 | 0.0000 | |
| SRP219564 | SLC39A1 | 27173 | RNAseq | 0.5922 | 0.0254 | |
| TCGA | SLC39A1 | 27173 | RNAseq | 0.0806 | 0.0759 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SLC39A1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of SLC39A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC39A1 | 27173 | 14 | 0 | 16 | |
| GSE20123 | SLC39A1 | 27173 | 14 | 0 | 16 | |
| GSE43470 | SLC39A1 | 27173 | 7 | 2 | 34 | |
| GSE46452 | SLC39A1 | 27173 | 2 | 1 | 56 | |
| GSE47630 | SLC39A1 | 27173 | 14 | 0 | 26 | |
| GSE54993 | SLC39A1 | 27173 | 0 | 4 | 66 | |
| GSE54994 | SLC39A1 | 27173 | 16 | 0 | 37 | |
| GSE60625 | SLC39A1 | 27173 | 0 | 0 | 11 | |
| GSE74703 | SLC39A1 | 27173 | 6 | 1 | 29 | |
| GSE74704 | SLC39A1 | 27173 | 7 | 0 | 13 | |
| TCGA | SLC39A1 | 27173 | 38 | 2 | 56 |
Total number of gains: 118; Total number of losses: 10; Total Number of normals: 360.
Somatic mutations of SLC39A1:
Generating mutation plots.
Highly correlated genes for SLC39A1:
Showing top 20/1433 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC39A1 | IRF2BPL | 0.861984 | 3 | 0 | 3 |
| SLC39A1 | RILPL1 | 0.818475 | 3 | 0 | 3 |
| SLC39A1 | ABCB6 | 0.813548 | 3 | 0 | 3 |
| SLC39A1 | UGGT2 | 0.789872 | 3 | 0 | 3 |
| SLC39A1 | YWHAG | 0.786032 | 4 | 0 | 4 |
| SLC39A1 | SSBP4 | 0.783359 | 3 | 0 | 3 |
| SLC39A1 | CYP27C1 | 0.777636 | 4 | 0 | 4 |
| SLC39A1 | IRF2BP2 | 0.773998 | 3 | 0 | 3 |
| SLC39A1 | CAMKK2 | 0.7664 | 4 | 0 | 4 |
| SLC39A1 | NCOR2 | 0.766187 | 5 | 0 | 5 |
| SLC39A1 | MZT1 | 0.760649 | 4 | 0 | 4 |
| SLC39A1 | PDE8A | 0.757984 | 3 | 0 | 3 |
| SLC39A1 | RTKN | 0.757403 | 5 | 0 | 5 |
| SLC39A1 | ZNF496 | 0.753528 | 4 | 0 | 4 |
| SLC39A1 | CHN1 | 0.751757 | 4 | 0 | 4 |
| SLC39A1 | GRAMD1A | 0.751622 | 3 | 0 | 3 |
| SLC39A1 | BAP1 | 0.746378 | 3 | 0 | 3 |
| SLC39A1 | SLC39A13 | 0.744329 | 4 | 0 | 3 |
| SLC39A1 | MB21D2 | 0.744234 | 4 | 0 | 4 |
| SLC39A1 | TMEM138 | 0.743617 | 5 | 0 | 5 |
For details and further investigation, click here
