HPCAL1

 

Full name: hippocalcin like 1 Alias Symbol: BDR1|HLP2|VILIP-3
Type: protein-coding gene Cytoband: 2p25.1
Entrez ID: 3241 HGNC ID: HGNC:5145 Ensembl Gene: ENSG00000115756 OMIM ID: 600207
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of HPCAL1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 HPCAL1 3241 212552_at 0.6904 0.0674
GSE20347 HPCAL1 3241 212552_at 0.9657 0.0000
GSE23400 HPCAL1 3241 212552_at 0.4452 0.0000
GSE26886 HPCAL1 3241 212552_at 0.9639 0.0000
GSE29001 HPCAL1 3241 212552_at 0.6653 0.0043
GSE38129 HPCAL1 3241 212552_at 0.7420 0.0001
GSE45670 HPCAL1 3241 212552_at 0.6854 0.0003
GSE53622 HPCAL1 3241 121546 0.7388 0.0000
GSE53624 HPCAL1 3241 121546 0.8535 0.0000
GSE63941 HPCAL1 3241 212552_at -0.0414 0.9510
GSE77861 HPCAL1 3241 212552_at 0.6608 0.0048
GSE97050 HPCAL1 3241 A_23_P5831 0.6152 0.1187
SRP007169 HPCAL1 3241 RNAseq 1.6211 0.0054
SRP008496 HPCAL1 3241 RNAseq 1.2254 0.0039
SRP064894 HPCAL1 3241 RNAseq 0.8921 0.0002
SRP133303 HPCAL1 3241 RNAseq 0.7165 0.0000
SRP159526 HPCAL1 3241 RNAseq 1.1644 0.0027
SRP193095 HPCAL1 3241 RNAseq 0.3000 0.3187
SRP219564 HPCAL1 3241 RNAseq 0.7969 0.0530
TCGA HPCAL1 3241 RNAseq -0.2960 0.0000

Upregulated datasets: 3; Downregulated datasets: 0.  

 

Survival by HPCAL1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of HPCAL1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 HPCAL1 3241 11 2 17
GSE20123 HPCAL1 3241 11 2 17
GSE43470 HPCAL1 3241 4 1 38
GSE46452 HPCAL1 3241 3 4 52
GSE47630 HPCAL1 3241 7 0 33
GSE54993 HPCAL1 3241 0 7 63
GSE54994 HPCAL1 3241 11 0 42
GSE60625 HPCAL1 3241 0 3 8
GSE74703 HPCAL1 3241 3 0 33
GSE74704 HPCAL1 3241 9 1 10
TCGA HPCAL1 3241 34 5 57

Total number of gains: 93; Total number of losses: 25; Total Number of normals: 370.  

 

Somatic mutations of HPCAL1:

 

Generating mutation plots.

 

Highly correlated genes for HPCAL1:

 

Showing top 20/1893 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
HPCAL1SLC39A30.821069404
HPCAL1SSBP40.777966505
HPCAL1SLC41A10.756853707
HPCAL1GRAMD1A0.751906707
HPCAL1CLPTM1L0.751437606
HPCAL1NEIL20.746753303
HPCAL1PYCR20.744202303
HPCAL1CHIC10.740832303
HPCAL1EFTUD20.735679606
HPCAL1NF10.734499303
HPCAL1ALKBH60.732972504
HPCAL1MARCKSL10.72324912011
HPCAL1PATZ10.723209707
HPCAL1PRPS1L10.722948303
HPCAL1ASB70.722607303
HPCAL1DNAJB110.721311606
HPCAL1TTC39C0.717242303
HPCAL1TEAD20.717197605
HPCAL1P2RX40.71504210010
HPCAL1MRPL100.71412303

For details and further investigation, click here