FNDC3B

 

Full name: fibronectin type III domain containing 3B Alias Symbol: FAD104|DKFZp762K137|FLJ23399|PRO4979|YVTM2421
Type: protein-coding gene Cytoband: 3q26.31
Entrez ID: 64778 HGNC ID: HGNC:24670 Ensembl Gene: ENSG00000075420 OMIM ID: 611909
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of FNDC3B:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 FNDC3B 64778 225032_at 0.8835 0.0480
GSE20347 FNDC3B 64778 218618_s_at 2.1648 0.0000
GSE23400 FNDC3B 64778 218618_s_at 1.5569 0.0000
GSE26886 FNDC3B 64778 225032_at 2.6374 0.0000
GSE29001 FNDC3B 64778 218618_s_at 2.1273 0.0000
GSE38129 FNDC3B 64778 218618_s_at 1.7951 0.0000
GSE45670 FNDC3B 64778 225032_at 0.4390 0.1830
GSE53622 FNDC3B 64778 13236 1.6406 0.0000
GSE53624 FNDC3B 64778 13236 1.6912 0.0000
GSE63941 FNDC3B 64778 218618_s_at -0.3076 0.5568
GSE77861 FNDC3B 64778 225032_at 1.7122 0.0049
GSE97050 FNDC3B 64778 A_33_P3296940 1.1025 0.0620
SRP007169 FNDC3B 64778 RNAseq 3.1816 0.0000
SRP008496 FNDC3B 64778 RNAseq 3.2243 0.0000
SRP064894 FNDC3B 64778 RNAseq 1.8787 0.0000
SRP133303 FNDC3B 64778 RNAseq 1.8716 0.0000
SRP159526 FNDC3B 64778 RNAseq 1.8041 0.0000
SRP193095 FNDC3B 64778 RNAseq 1.6344 0.0000
SRP219564 FNDC3B 64778 RNAseq 1.3134 0.0138
TCGA FNDC3B 64778 RNAseq 0.0734 0.2646

Upregulated datasets: 15; Downregulated datasets: 0.  

 

Survival by FNDC3B expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of FNDC3B:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 FNDC3B 64778 24 0 6
GSE20123 FNDC3B 64778 24 0 6
GSE43470 FNDC3B 64778 23 0 20
GSE46452 FNDC3B 64778 19 1 39
GSE47630 FNDC3B 64778 27 2 11
GSE54993 FNDC3B 64778 1 15 54
GSE54994 FNDC3B 64778 41 0 12
GSE60625 FNDC3B 64778 0 6 5
GSE74703 FNDC3B 64778 19 0 17
GSE74704 FNDC3B 64778 16 0 4
TCGA FNDC3B 64778 80 0 16

Total number of gains: 274; Total number of losses: 24; Total Number of normals: 190.  

 

Somatic mutations of FNDC3B:

 

Generating mutation plots.

 

Highly correlated genes for FNDC3B:

 

Showing top 20/1968 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
FNDC3BLPCAT10.83855911011
FNDC3BMFAP20.82569411011
FNDC3BFMNL20.81924707
FNDC3BPLOD10.81877611011
FNDC3BCTHRC10.808347808
FNDC3BPLAU0.80474311011
FNDC3BTMEM2630.80353606
FNDC3BTP53I130.788407606
FNDC3BPLXNA10.78827511011
FNDC3BPYCR20.787662303
FNDC3BGPX80.78751707
FNDC3BLAPTM4B0.78584911011
FNDC3BTTYH30.783882707
FNDC3BFADS10.780674303
FNDC3BPLOD30.77882111011
FNDC3BENAH0.77755611011
FNDC3BCOL4A10.77578812011
FNDC3BGNA120.77571611011
FNDC3BPTK20.77546411011
FNDC3BTRIO0.76962211011

For details and further investigation, click here