| Full name: glutathione S-transferase alpha 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 6p12.2 | ||
| Entrez ID: 2938 | HGNC ID: HGNC:4626 | Ensembl Gene: ENSG00000243955 | OMIM ID: 138359 |
| Drug and gene relationship at DGIdb | |||
Expression of GSTA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GSTA1 | 2938 | 215766_at | -0.0691 | 0.7785 | |
| GSE20347 | GSTA1 | 2938 | 215766_at | -0.0769 | 0.4869 | |
| GSE23400 | GSTA1 | 2938 | 215766_at | -0.3020 | 0.0000 | |
| GSE26886 | GSTA1 | 2938 | 215766_at | -0.1291 | 0.6074 | |
| GSE29001 | GSTA1 | 2938 | 215766_at | -0.4243 | 0.1335 | |
| GSE38129 | GSTA1 | 2938 | 215766_at | -0.2435 | 0.0119 | |
| GSE45670 | GSTA1 | 2938 | 215766_at | -0.1913 | 0.1529 | |
| GSE63941 | GSTA1 | 2938 | 215766_at | -0.6664 | 0.0252 | |
| GSE77861 | GSTA1 | 2938 | 215766_at | -0.0442 | 0.7632 | |
| SRP007169 | GSTA1 | 2938 | RNAseq | 0.6714 | 0.4872 | |
| SRP159526 | GSTA1 | 2938 | RNAseq | 2.5757 | 0.0182 | |
| TCGA | GSTA1 | 2938 | RNAseq | -1.1028 | 0.1974 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by GSTA1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of GSTA1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GSTA1 | 2938 | 7 | 2 | 21 | |
| GSE20123 | GSTA1 | 2938 | 7 | 2 | 21 | |
| GSE43470 | GSTA1 | 2938 | 5 | 0 | 38 | |
| GSE46452 | GSTA1 | 2938 | 2 | 10 | 47 | |
| GSE47630 | GSTA1 | 2938 | 7 | 5 | 28 | |
| GSE54993 | GSTA1 | 2938 | 3 | 1 | 66 | |
| GSE54994 | GSTA1 | 2938 | 8 | 4 | 41 | |
| GSE60625 | GSTA1 | 2938 | 0 | 3 | 8 | |
| GSE74703 | GSTA1 | 2938 | 5 | 0 | 31 | |
| GSE74704 | GSTA1 | 2938 | 3 | 1 | 16 | |
| TCGA | GSTA1 | 2938 | 22 | 12 | 62 |
Total number of gains: 69; Total number of losses: 40; Total Number of normals: 379.
Somatic mutations of GSTA1:
Generating mutation plots.
Highly correlated genes for GSTA1:
Showing top 20/140 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GSTA1 | SLC5A7 | 0.670219 | 4 | 0 | 4 |
| GSTA1 | AQP4 | 0.654351 | 3 | 0 | 3 |
| GSTA1 | ZNF329 | 0.653904 | 3 | 0 | 3 |
| GSTA1 | ZMAT4 | 0.626043 | 3 | 0 | 3 |
| GSTA1 | SLC19A2 | 0.62382 | 3 | 0 | 3 |
| GSTA1 | SLC2A2 | 0.623152 | 3 | 0 | 3 |
| GSTA1 | ZNF432 | 0.621728 | 3 | 0 | 3 |
| GSTA1 | UBQLN3 | 0.619192 | 3 | 0 | 3 |
| GSTA1 | WNT16 | 0.617503 | 3 | 0 | 3 |
| GSTA1 | OR5I1 | 0.617284 | 4 | 0 | 4 |
| GSTA1 | TSC1 | 0.609836 | 3 | 0 | 3 |
| GSTA1 | SGK2 | 0.60594 | 4 | 0 | 4 |
| GSTA1 | SYT13 | 0.602504 | 3 | 0 | 3 |
| GSTA1 | ZNF717 | 0.598849 | 5 | 0 | 3 |
| GSTA1 | OR10H3 | 0.598648 | 4 | 0 | 4 |
| GSTA1 | STS | 0.595208 | 3 | 0 | 3 |
| GSTA1 | RNASE3 | 0.592504 | 3 | 0 | 3 |
| GSTA1 | PSG4 | 0.592116 | 4 | 0 | 3 |
| GSTA1 | RAVER2 | 0.591967 | 5 | 0 | 3 |
| GSTA1 | G6PC2 | 0.591208 | 4 | 0 | 3 |
For details and further investigation, click here
